Respiratory system | |||||
---|---|---|---|---|---|
Respiratory system / Respiratory depression, respiratory distress syndrome and apnoea | |||||
doxapram hydrochloride | Hospital Only | ||||
Solution for injection | |||||
Doxapram hydrochloride (Non-proprietary) | |||||
Respiratory system / Airways disease, obstructive | |||||
aclidinium bromide | On Formulary | ||||
Barts Health COPD Algorithm
|
|||||
Eklira Genuair (Aclidinium)
Eklira Genuair (Aclidinium) Dry Powder Inhaler- requires Quick and Deep breath/ inspiratory effort. Note that all inhalers should be prescribed by Brand and Device Names.
|
|||||
Duaklir Genuair 340mcg/12mcg (Aclidinium and Formoterol)
Dry Powder Inhaler. Requires Quick and Deep Breath/ Inspiratory effort. All Inhalers should be prescribed by Brand and Device Names. |
|||||
Inhalation powder | |||||
Eklira (Covis Pharma GmbH) | On Formulary | ||||
Aclidinium 340 / formoterol 12 inhaler
Approved for use in COPD.
|
|||||
Aclidinium
Aclidinium is second line for persistent breathlessness in COPD. |
|||||
aclidinium bromide with formoterol | On Formulary | ||||
Duaklir Genuair 340mcg/12mcg (Aclidinium and Formoterol)
Dry Powder Inhaler. Requires Quick and Deep Breath/ Inspiratory effort. All Inhalers should be prescribed by Brand and Device Names. |
|||||
Inhalation powder | |||||
Duaklir (Covis Pharma GmbH) | On Formulary | ||||
Aclidinium
Aclidinium is second line for persistent breathlessness in COPD. |
|||||
Aclidinium 340 / formoterol 12 inhaler
Approved for use in COPD.
|
|||||
aminophylline | On Formulary | ||||
AMINOPHYLLINE
INJECTION FORMULATION IS HOSPITAL USE ONLY |
|||||
Solution for injection | |||||
Aminophylline (Non-proprietary) | Hospital Only | ||||
Aminophylline
INJECTION FORMULATION IS FOR HOSPITAL USE ONLY |
|||||
beclometasone dipropionate | On Formulary | ||||
Clenil Modulite MDI 100micrograms per actuation
Metered Dose Inhaler. Requires Slow and Steady Breath. Suitable for patients with low Inspiratory effort. All Inhalers should be prescribed by Brand and Device Names. |
|||||
Modified-release tablet | |||||
Clipper (Chiesi Ltd) | |||||
Pressurised inhalation | |||||
Beclu (Lupin Healthcare (UK) Ltd) | |||||
Clenil Modulite (Chiesi Ltd) | |||||
Kelhale (Cipla EU Ltd) | |||||
Qvar (Teva UK Ltd) | |||||
Qvar Autohaler (Teva UK Ltd) | |||||
Qvar Easi-Breathe (Teva UK Ltd) | |||||
Soprobec (Glenmark Pharmaceuticals Europe Ltd) | |||||
Inhalation powder | |||||
Easyhaler (Orion Pharma (UK) Ltd) | On Formulary | ||||
Spray | |||||
Beclometasone dipropionate (Non-proprietary) | |||||
Beconase (GlaxoSmithKline UK Ltd, Omega Pharma Ltd) | |||||
Nasobec (Teva UK Ltd) | |||||
Cutaneous ointment | |||||
Beclometasone dipropionate (Non-proprietary) | |||||
Cutaneous cream | |||||
Beclometasone dipropionate (Non-proprietary) | |||||
beclometasone with formoterol | On Formulary | ||||
Fostair 100/6 and 200/6 Strengths available as both Nexthaler and MDI Devices
Nexthaler Device is a Dry Powder Inhaler. Requires Quick and Deep Breath/ Inspiratory effort. Metered Dose Inhaler. Requires Slow and Steady Breath. Suitable for patients with low Inspiratory effort. All Inhalers should be prescribed by Brand and Device Names.
Note that only Fostair 100/6 strength in both the Nexthaler and MDI devices are licensed in both Asthma and COPD. The 200/6 strength for both devices are licensed only for asthma. |
|||||
Pressurised inhalation | |||||
Beclometasone with formoterol (Non-proprietary) | |||||
Bibecfo (Cipla EU Ltd) | |||||
Fostair (Chiesi Ltd) | |||||
Luforbec (Lupin Healthcare (UK) Ltd) | |||||
Inhalation powder | |||||
Fostair NEXThaler (Chiesi Ltd) | On Formulary | ||||
Barts Health & Local GPs Asthma Prescribing Guidelines
see attached |
|||||
Fostair®
Refer to attached guidelines for treatment of Asthma
|
|||||
beclometasone with formoterol and glycopyrronium | On Formulary | ||||
Trimbow 87mcg/5mcg/9mcg MDI
Metered Dose Inhaler. Requires Slow and Steady Breath. Suitable for patients with low Inspiratory effort. All Inhalers should be prescribed by Brand and Device Names. |
|||||
Pressurised inhalation | |||||
Trimbow (Chiesi Ltd) | |||||
Inhalation powder | |||||
Trimbow NEXThaler (Chiesi Ltd) | |||||
benralizumab | Hospital Only |
NICE TA565 |
|||
Benralizumab 30mg pre filled syringe for subcutaneous injection
To be initiated only after Severe Asthma MDT discussion at St. Bartholomew's Hospital. CONSULTANT INITIATION ONLY Currently funded via Trust approved Patient Access Scheme until NHSE commissioning (pending 2nd quater 2019) |
|||||
Solution for injection | |||||
Fasenra (AstraZeneca UK Ltd) | |||||
budesonide | On Formulary |
NICE TA708 NICE TA937 |
|||
NICE TA 937 -March 2024- Budesonide treating for primary IgA nephropathy (HCD)
Budesonide approved at NEL FPG treating for primary IgA nephropathy (HCD)
Formulary Status: Hospital Only |
|||||
Budesonide 64micrograms/ acuation nasal spray
Budesonide Nasal spray is not our 1st line intranasal corticosteroid. |
|||||
Budesonide orodispersible tablets
Budesonide orodispersible tablet for inducing remission of eosinophilic oesophagitis as per NICE TA708 Approved as Hospital Only. September 2021 DTC. |
|||||
Pulmicort 200mcg Turbohaler
Dry Powder Inhaler. Requires Quick and Deep Breath/ Inspiratory effort. All Inhalers should be prescribed by Brand and Device Names. |
|||||
Orodispersible tablet | |||||
Jorveza (Dr. Falk Pharma UK Ltd) | |||||
Modified-release tablet | |||||
Cortiment (Ferring Pharmaceuticals Ltd) | |||||
Modified-release capsule | |||||
Budesonide (Non-proprietary) | |||||
Kinpeygo (Genus Pharmaceuticals Holdings Ltd) | |||||
Gastro-resistant capsule | |||||
Budenofalk (Dr. Falk Pharma UK Ltd) | |||||
Gastro-resistant granules | |||||
Budenofalk (Dr. Falk Pharma UK Ltd) | |||||
Inhalation powder | |||||
Budelin Novolizer (Viatris UK Healthcare Ltd) | |||||
Easyhaler (Orion Pharma (UK) Ltd) | |||||
Pulmicort Turbohaler (AstraZeneca UK Ltd) | On Formulary | ||||
Barts Health & Local GPs Asthma Prescribing Guidelines
see attached |
|||||
Nebuliser liquid | |||||
Budesonide (Non-proprietary) | |||||
Pulmicort Respules (AstraZeneca UK Ltd) | |||||
Enema | |||||
Entocort (Tillotts Pharma UK Ltd) | |||||
Spray | |||||
Budesonide (Non-proprietary) | |||||
Rectal foam | |||||
Budenofalk (Dr. Falk Pharma UK Ltd) | |||||
budesonide with formoterol | On Formulary | ||||
Inspiratory effort of different devices
Note that the Spiromax and Turbohaler devices require similar inspiratory effort to use effectively. Fobumix Easyhaler is NOT ON FORMULARY. Easyhalers requires higher inspiratory effort than Turbohaler and Spiromax devices. |
|||||
Symbicort 100/6; 200/6; 400/12 Turbohalers and 200/6 MDI
Turbohaler device is a Dry Powder Inhaler. Requires Quick and Deep Breath/ Inspiratory effort. Metered Dose Inhaler device requires Slow and Steady Breath. Suitable for patients with low Inspiratory effort. All Inhalers should be prescribed by Brand and Device Names. Note that Symbicort 200/6 and 400/12 Turbohaler are licensed for both Asthma and COPD. Symbicort 100/6 Turbohaler is licensed ONLY for Asthma. Symbicort 200/6 MDI is the only strength in the MDI device and currently licensed only in COPD. Please recommend use via an aerochamber. |
|||||
Pressurised inhalation | |||||
Symbicort (AstraZeneca UK Ltd) | |||||
Inhalation powder | |||||
DuoResp Spiromax (Teva UK Ltd) | On Formulary | ||||
Fobumix Easyhaler (Orion Pharma (UK) Ltd) | |||||
Symbicort Turbohaler (AstraZeneca UK Ltd) | On Formulary | ||||
BTS/SIGN Guidelines On The Management Of Asthma
see attached |
|||||
Barts Health & Local GPs Asthma Prescribing Guidelines
see attached |
|||||
Symbicort®
Refer to attached guidelines for treatment of Asthma
Also see COPD action plan-staying well with COPD |
|||||
Barts Health & Local GPs Asthma Prescribing Guidelines
see attached |
|||||
WockAIR (Wockhardt UK Ltd) | |||||
ciclesonide | On Formulary | ||||
Alvesco MDI
Metered Dose Inhaler. Requires Slow and Steady Breath. Suitable for patients with low Inspiratory effort. All Inhalers should be prescribed by Brand and Device Names. Recommended to be used via an aerochamber device. Alvesco MDI is not first line inhaled corticosteroid for asthma. Please see attached bart's Asthma guidelines. |
|||||
Pressurised inhalation | |||||
Alvesco (Covis Pharma GmbH) | |||||
dupilumab | Hospital Only |
NICE TA534 NICE TA751 NICE TA955 |
|||
Solution for injection | |||||
Dupixent (Sanofi) | |||||
ephedrine hydrochloride | Off Formulary | ||||
Inhaled Ephedrine (Primatene Mist)- Non-formulary
Inhaled Ephedrine is not recommended for the treatment of asthma. Please contact the Pharmacy respiratory team for advice if ever prescribed for asthma. Please contact Emergency Medicine Lead Pharmacist for advice if prescribed for patient in ED. |
|||||
Solution for injection | |||||
Ephedrine hydrochloride (Non-proprietary) | |||||
Oral tablet | |||||
Ephedrine hydrochloride (Non-proprietary) | |||||
fluticasone | On Formulary | ||||
Flixotide 50micrograms MDI and 100micrograms Accuhaler
Accuhaler is a Dry Powder Inhaler. Requires Quick and Deep Breath/ Inspiratory effort. Metered Dose Inhaler requires Slow and Steady Breath. Suitable for patients with low Inspiratory effort. All Inhalers should be prescribed by Brand and Device Names. See its place in therapy using attached Bart's Adult Asthma Guidelines. |
|||||
Fluticasone Nasal Sprays- Please specify brand and Salt
NOTE: Available as Fluticasone PROPIONATE available as Flixonase Brand 50mcg/spray Dose: 100mcg (2sprays) into both nostrils OD up to 100mcg (2sp) into both nostrils BD
Avamys® (Fluticasone FUROATE) 27.5mcg/ spray Dose: 55mcg (2sprays) into both nostrils OD. |
|||||
Pressurised inhalation | |||||
Flixotide Evohaler (GlaxoSmithKline UK Ltd) | |||||
Inhalation powder | |||||
Flixotide Accuhaler (GlaxoSmithKline UK Ltd) | On Formulary | ||||
Spray | |||||
Fluticasone (Non-proprietary) | |||||
Avamys (GlaxoSmithKline UK Ltd) | |||||
Allergic Rhinitis Pathway
Allergic Rhinitis Pathway |
|||||
Coryen (Alissa Healthcare Research Ltd) | |||||
Flixonase (GlaxoSmithKline UK Ltd, Haleon UK Trading Ltd) | |||||
Nasofan (Teva UK Ltd) | |||||
Nasal drops | |||||
Fluticasone (Non-proprietary) | |||||
Cutaneous ointment | |||||
Cutivate (GlaxoSmithKline UK Ltd) | |||||
Cutaneous cream | |||||
Fluticasone (Non-proprietary) | |||||
fluticasone with formoterol | On Formulary | ||||
Flutiform 50/5; 125/5; 250/10 micrograms MDI
Licensed only in Asthma Metered Dose Inhaler. Requires Slow and Steady Breath. Suitable for patients with low Inspiratory effort. All Inhalers should be prescribed by Brand and Device Names. |
|||||
Pressurised inhalation | |||||
Flutiform (Napp Pharmaceuticals Ltd) | |||||
fluticasone with salmeterol | On Formulary | ||||
Prescribe by Brand and Device
Seretide Accuhalers and AirFluSal Fospiro are Dry Powder Inhaler devices. Requires Quick and Deep Breath/ Inspiratory effort. Metered Dose Inhaler. Requires Slow and Steady Breath. Suitable for patients with low Inspiratory effort. All Inhalers should be prescribed by Brand and Device Names. Currently at Barts Health, we only have AirFluSal MDI and Seretide MDI Brands available. All adult patients should be prescribed AirFluSal MDI Brand for asthma management. - see attached Memo for Seretide to AirFluSal MDI switch in Adult pateints. Seretide MDI should be reserved only for Paediatric patients only.
|
|||||
Pressurised inhalation | |||||
AirFluSal (Sandoz Ltd) | |||||
Aloflute (Viatris UK Healthcare Ltd) | |||||
Avenor (Zentiva Pharma UK Ltd) | |||||
Combisal (Aspire Pharma Ltd) | |||||
Sereflo (Cipla EU Ltd) | |||||
Seretide Evohaler (GlaxoSmithKline UK Ltd) | |||||
Sirdupla (Viatris UK Healthcare Ltd) | |||||
Inhalation powder | |||||
AirFluSal Forspiro (Sandoz Ltd) | |||||
Campona Airmaster (Genesis Pharmaceuticals Ltd) | |||||
Fixkoh Airmaster (Genus Pharmaceuticals Holdings Ltd) | |||||
Fusacomb Easyhaler (Orion Pharma (UK) Ltd) | |||||
Sereflo Ciphaler (Cipla EU Ltd) | |||||
Seretide Accuhaler (GlaxoSmithKline UK Ltd) | |||||
Stalpex (Glenmark Pharmaceuticals Europe Ltd) | |||||
fluticasone with umeclidinium and vilanterol | On Formulary | ||||
Trelegy Ellipta 92/55/22
Dry Powder Inhaler. Requires Quick and Deep Breath/ Inspiratory effort. All Inhalers should be prescribed by Brand and Device Names. |
|||||
Inhalation powder | |||||
Trelegy Ellipta (GlaxoSmithKline UK Ltd) | On Formulary | ||||
fluticasone with vilanterol | On Formulary | ||||
Inhalation powder | |||||
Relvar Ellipta (GlaxoSmithKline UK Ltd) | On Formulary | ||||
formoterol fumarate | On Formulary | ||||
Pressurised inhalation | |||||
Atimos Modulite (Chiesi Ltd) | |||||
Inhalation powder | |||||
Easyhaler (Orion Pharma (UK) Ltd) | On Formulary | ||||
Oxis Turbohaler (AstraZeneca UK Ltd) | On Formulary | ||||
formoterol fumarate with glycopyrronium and budesonide | |||||
Pressurised inhalation | |||||
Formoterol fumarate with glycopyrronium and budesonide (Non-proprietary) | |||||
glycopyrronium bromide | On Formulary | ||||
Prescribing in Palliative Care
Palliative Care Team Contacts:
|
|||||
Seebri Breezhaler 44mcg Capsules for Inhalation
Breezhaler is a Dry Powder Inhaler and requires Quick and Deep Inspiratory effort. Always prescribe by Brand and Device |
|||||
Solution for injection | |||||
Glycopyrronium bromide (Non-proprietary) | |||||
Inhalation powder | |||||
Seebri Breezhaler (Novartis Pharmaceuticals UK Ltd) | On Formulary | ||||
glycopyrronium with formoterol fumarate | |||||
Pressurised inhalation | |||||
Bevespi Aerosphere (AstraZeneca UK Ltd) | |||||
glycopyrronium with indacaterol | On Formulary | ||||
Ultibro Breezhaler 85/43mcg Capsule for inhalation
Breezhaler is a dry powder inhaler and requires a Quick and Deep inspiratory effort. Always prescribe by Brand and Device |
|||||
Inhalation powder | |||||
Ultibro Breezhaler (Novartis Pharmaceuticals UK Ltd) | On Formulary | ||||
human alpha<sub>1</sub>-proteinase inhibitor | Off Formulary | ||||
NICE evaluation on Human alpha1-proteinase inhibitor for treating emphysema ID856
Currently under consultation. [GID-HST10017] Expected publication date: 10 July 2019 Will be in the context of NHSE commissioning by a specialist service. |
|||||
Powder and solvent for solution for infusion | |||||
Respreeza (CSL Behring UK Ltd) | |||||
indacaterol | On Formulary | ||||
Onbrez Breezhaler 150 and 300mcg strength Capule for inhalation
Breezhaler is a Dry Powder Inhaler and requires Quick and Deep inspiratory effort
Always prescribe by Brand and Device |
|||||
Inhalation powder | |||||
Onbrez Breezhaler (Novartis Pharmaceuticals UK Ltd) | On Formulary | ||||
indacaterol with mometasone furoate | |||||
Inhalation powder | |||||
Atectura Breezhaler (Novartis Pharmaceuticals UK Ltd) | |||||
ipratropium bromide | On Formulary | ||||
Pressurised inhalation | |||||
Atrovent (Boehringer Ingelheim Ltd) | |||||
Inhalvent (Alissa Healthcare Research Ltd) | |||||
Nebuliser liquid | |||||
Ipratropium bromide (Non-proprietary) | |||||
Atrovent UDV (Boehringer Ingelheim Ltd) | |||||
Spray | |||||
Ipratropium bromide (Non-proprietary) | |||||
ipratropium with salbutamol | Off Formulary | ||||
Nebuliser liquid | |||||
Combiprasal (TriOn Pharma Ltd) | |||||
Combivent (Boehringer Ingelheim Ltd) | |||||
Ipramol (Teva UK Ltd) | |||||
mepolizumab | Hospital Only |
NICE TA671 |
|||
Mepolizumab 100mg powder for subcutaneous injection
To be initiated only after Severe Asthma MDT discussion at St. Bartholomew's Hospital. CONSULTANT INITIATION ONLY |
|||||
Solution for injection | |||||
Nucala (GlaxoSmithKline UK Ltd) | |||||
Powder for solution for injection | |||||
Nucala (GlaxoSmithKline UK Ltd) | |||||
mometasone furoate | Off Formulary | ||||
Inhalation powder | |||||
Asmanex Twisthaler (Organon Pharma (UK) Ltd) | |||||
Spray | |||||
Mometasone furoate (Non-proprietary) | |||||
Nasonex (Organon Pharma (UK) Ltd) | |||||
Cutaneous ointment | |||||
Mometasone furoate (Non-proprietary) | |||||
Elocon (Organon Pharma (UK) Ltd) | |||||
Cutaneous cream | |||||
Mometasone furoate (Non-proprietary) | |||||
Elocon (Organon Pharma (UK) Ltd) | |||||
Cutaneous liquid | |||||
Elocon (Organon Pharma (UK) Ltd) | |||||
mometasone furoate with glycopyrronium bromide and indacaterol | On Formulary | ||||
Mometasone furoate with glycopyrronium and indacterol for maintenance treatment of asthma in adult patients
Approved at DTC July 2022 for maintenance treatment of asthma in adult patients not adequately controlled with a maintenance combination of a long-acting beta2 -agonist and a high dose of an inhaled corticosteroid who experienced one or more asthma exacerbations in the previous year |
|||||
Inhalation powder | |||||
Enerzair Breezhaler (Novartis Pharmaceuticals UK Ltd) | |||||
Management of Asthma (July 2022)
Enerzair Breezhaler for maintenance treatment of asthma in adult patients not adequately controlled with a maintenance combination of a long-acting beta2 -agonist and a high dose of an inhaled corticosteroid who experienced one or more asthma exacerbations in the previous year |
|||||
montelukast | On Formulary | ||||
MONTELUKAST
NOTE: SINGULAIR 10MG CHEWABLE TABLETS ON FORMULARY ONLY |
|||||
MONTELUKAST
NOTE: SINGULAIR 10MG CHEWABLE TABLETS ON FORMULARY ONLY |
|||||
Barts Health Asthma Prescribing Guidelines
See Barts health asthma guidelines for place in therapy |
|||||
Chewable tablet | |||||
Montelukast (Non-proprietary) | On Formulary | ||||
Barts Health & Local GPs Asthma Prescribing Guidelines
Asthma Update April 2015 |
|||||
MONTELUKAST
NOTE: SINGULAIR 10MG CHEWABLE TABLETS ON FORMULARY ONLY |
|||||
Singulair (Organon Pharma (UK) Ltd) | On Formulary | ||||
Barts Health & Local GPs Asthma Prescribing Guidelines
Asthma Update April 2015 |
|||||
MONTELUKAST
NOTE: SINGULAIR 10MG CHEWABLE TABLETS ON FORMULARY ONLY |
|||||
Oral tablet | |||||
Montelukast (Non-proprietary) | |||||
Singulair (Organon Pharma (UK) Ltd) | |||||
Oral granules | |||||
Montelukast (Non-proprietary) | |||||
Singulair (Organon Pharma (UK) Ltd) | |||||
olodaterol | Off Formulary | ||||
Striverdi Respimat 2.5 microgram, solution for inhalation
Respimat device is a soft mist inhaler device and requires a Slow and Steady inspiratory effort. Always prescribe as Brand and Device |
|||||
Inhalation solution | |||||
Striverdi Respimat (Boehringer Ingelheim Ltd) | |||||
omalizumab | Hospital Only |
NICE TA278 NICE TA339 |
|||
OMALIZUMAB
Only approved for specialist commissioned centres such as Barts Health as per NHS specialist commissioning for severe allergic asthma. Also used for Chronic Spontaneous Urticaria as a specialist Allergy Center. Both indications require initiation by consultant only and after discussion at the severe asthma and Allergy MDT respectively.
|
|||||
Solution for injection | |||||
Omalizumab (Non-proprietary) | |||||
Xolair (Novartis Pharmaceuticals UK Ltd) | On Formulary | ||||
OMALIZUMAB
Only approved for specialist commissioned centres as per NHS specialist commissioning (currently approved centres are Barts Health, Royal Brompton and Guy's & St Thomas' for asthma and Barts Health is one of the centres for Chronic Spontaneous Urticaria) |
|||||
Omalizumab for Chronic Spontaneous Urticaria
|
|||||
reslizumab | Hospital Only |
NICE TA479 |
|||
Reslizumab
To be initiated only after Severe Asthma MDT discussion at St. Bartholomew's Hospital. CONSULTANT INITIATION ONLY |
|||||
Solution for infusion | |||||
Cinqaero (Teva UK Ltd) | |||||
roflumilast | On Formulary |
NICE TA461 |
|||
Roflumilast
COPD Specialist consultant initiation only. To be initiated and monitored by secondary care until patient is stable on treatment before primary care takes over ongoing monitoring and prescribing. |
|||||
Oral tablet | |||||
Roflumilast (Non-proprietary) | |||||
Daxas (AstraZeneca UK Ltd) | |||||
salbutamol | On Formulary | ||||
Barts Health Asthma Guidelines
see attached |
|||||
February 2024 - Salbutamol 100 microgram metered dose inhaler (MDI) for the treatment of acute bronchospasm in anaesthetised patients directly via a breathing circuit (off-label)
Salbutamol 100 microgram metered dose inhaler (MDI) approved at NEL FPG for the treatment of acute bronchospasm in anaesthetised patients directly via a breathing circuit (off-label) *Use of salbutamol MDI directly via a breathing circuit as an alternative to salbutamol nebulisation
Hospital Only |
|||||
SALBUTAMOL
IV FORMULATION IS FOR HOSPITAL USE ONLY |
|||||
Solution for injection | |||||
Ventolin (GlaxoSmithKline UK Ltd) | Hospital Only | ||||
Parenteral
Hospital Only Drug |
|||||
Solution for infusion | |||||
Ventolin (GlaxoSmithKline UK Ltd) | Hospital Only | ||||
Pressurised inhalation | |||||
Airomir (Teva UK Ltd) | |||||
Airomir Autohaler (Teva UK Ltd) | |||||
Salamol (Teva UK Ltd) | |||||
Salamol Easi-Breathe (Teva UK Ltd) | |||||
Ventolin Evohaler (GlaxoSmithKline UK Ltd) | |||||
Inhalation powder | |||||
Easyhaler (Orion Pharma (UK) Ltd) | |||||
Salbulin Novolizer (Viatris UK Healthcare Ltd) | |||||
Ventolin Accuhaler (GlaxoSmithKline UK Ltd) | |||||
Nebuliser liquid | |||||
Salbutamol (Non-proprietary) | |||||
Ventolin (GlaxoSmithKline UK Ltd) | |||||
salmeterol | On Formulary | ||||
Severent MDI and Accuhaler
Accuhaler is a dry powder device and requires a Quick and Deep inspiratory effort. MDI devices requires a Slow and Steady inspiratory effort. Always prescribe by Brand and Device |
|||||
Pressurised inhalation | |||||
Serevent Evohaler (GlaxoSmithKline UK Ltd) | |||||
Soltel (Cipla EU Ltd) | |||||
Inhalation powder | |||||
Serevent Accuhaler (GlaxoSmithKline UK Ltd) | On Formulary | ||||
terbutaline sulfate | On Formulary | ||||
TERBUTALINE SULFATE
INJECTION FORMULATION IS FOR HOSPITAL USE ONLY |
|||||
Bricanyl Turbohaler 500mcg/ dose
Turbohalers are dry powder inhaler devices and require a Quick and Deep inspiratory effort. Always prescribe by Brand and Device. |
|||||
Solution for injection | |||||
Bricanyl (AstraZeneca UK Ltd) | On Formulary | ||||
Bricanyl®
Terbutaline injection is a Hospital Only Drug |
|||||
Inhalation powder | |||||
Bricanyl Turbohaler (AstraZeneca UK Ltd) | On Formulary | ||||
Nebuliser liquid | |||||
Terbutaline sulfate (Non-proprietary) | |||||
Bricanyl Respules (AstraZeneca UK Ltd) | |||||
Oral tablet | |||||
Bricanyl (AstraZeneca UK Ltd) | |||||
tezepelumab | On Formulary |
NICE TA880 |
|||
Tezepelumab (FOC) for severe asthma, February 2023
Approved at NEL FPG for adult or adolescent patients 12 years and older with severe asthma who are inadequately controlled despite high-dose inhaled corticosteroids plus another medicinal product for maintenance treatment, and has either had 3 or more asthma exacerbations needing systemic corticosteroids in the previous 12 months or treatment with continuous oral corticosteroids over the previous 6 months. To be used when current NICE-approved treatments are not appropriate. Hospital Only (Red) |
|||||
NICE TA 880 - June 2023 - Tezepelumab for treating severe asthma in people 12 years and over.
Tezepelumab approved at NEL FPG for treating severe asthma in line with NICE TA 880. |
|||||
Solution for injection | |||||
Tezspire (AstraZeneca UK Ltd) | |||||
theophylline | On Formulary | ||||
Theophylline
See attached guidelines |
|||||
Modified-release tablet | |||||
Uniphyllin Continus (Ennogen Healthcare Ltd) | On Formulary | ||||
BTS/SIGN Guidelines On The Management Of Asthma
see attached |
|||||
Barts Health & Local GPs Asthma Prescribing Guidelines
Asthma update April 2015 |
|||||
Barts Health & Local GPs Asthma Prescribing Guideline
Barts Health & Local GPs Asthma Prescribing Guideline |
|||||
tiotropium | On Formulary | ||||
Tiotropium
Tiotropium exists as: Spiriva handihaler 18mcg capsule for inhalation- Dry powder; requires Quick and Deep inspiratory effort Braltus Zonda 10mcg capsule for inhalation-Dry powder; requires Quick and Deep inspiratory effort Spiriva Respimat 2.5mcg strength soft mist inhaler- requires a Slow and Steady inspiratory effort Always prescribe by Brand and Device |
|||||
Respimat inhaler (new presentation of Tiotropium), June 2009
The Group recommended the use of Respimat, a new presentation of Tiotropium inhaler, as follows:
Doctors will need to state device and dose required on prescriptions for tiotropium. The dose for the two devices is different.
|
|||||
Inhalation powder | |||||
Acopair (Viatris UK Healthcare Ltd) | |||||
Braltus (Teva UK Ltd) | |||||
Spiriva (Boehringer Ingelheim Ltd) | On Formulary | ||||
Tiogiva (Glenmark Pharmaceuticals Europe Ltd) | |||||
Inhalation solution | |||||
Spiriva Respimat (Boehringer Ingelheim Ltd) | |||||
tiotropium with olodaterol | On Formulary | ||||
Spiolto Respimat 2.5 microgram/2.5 microgram, inhalation solution
Respimat is a soft mist inahler device and requires a slow and steady inspiratory effort Always prescribe by Brand and Device |
|||||
Inhalation solution | |||||
Spiolto Respimat (Boehringer Ingelheim Ltd) | |||||
umeclidinium | On Formulary | ||||
Incruse Ellipta inhaler
Ellipta device is a dry powder device and requires a Quick and Deep inspiratory effort Always prescribe by Brand and Device |
|||||
Inhalation powder | |||||
Incruse Ellipta (GlaxoSmithKline UK Ltd) | On Formulary | ||||
Umeclidinium inhaler
|
|||||
umeclidinium with vilanterol | On Formulary | ||||
Anoro Ellipta 55 micrograms/22 micrograms inhalation powder, pre-dispensed
Ellipta device is a dry powder device and requires a Quick and Deep inspiratory effort Always prescribe by Brand and Device |
|||||
Inhalation powder | |||||
Anoro Ellipta (GlaxoSmithKline UK Ltd) | On Formulary | ||||
Anoro Ellipta inhaler
Anoro Ellipta (umeclidinium/vilanterol 55/22mcg) as combination LAMA/LABA for COPD to be used as a step-up from single LAMA or LABA therapy, or as an alternative to triple therapy, both being for patients formally assessed as at low risk of exacerbation. |
|||||
Respiratory system / Cough and congestion | |||||
citric acid | On Formulary | ||||
Citric Acid
Commonly known as Simple Lintus |
|||||
Oral solution | |||||
Citric acid (Non-proprietary) | On Formulary | ||||
Citric acid
Commonly known as Simple Lintus |
|||||
codeine phosphate | On Formulary | ||||
Codeine Lintus 15mg/5ml for cough
The therapeutic indication is as an anti-tussive in a non-productive cough. |
|||||
Oral solution | |||||
Codeine phosphate (Non-proprietary) | On Formulary | ||||
Galcodine (Thornton & Ross Ltd) | |||||
Oral tablet | |||||
Codeine phosphate (Non-proprietary) | |||||
eucalyptus with menthol | Off Formulary | ||||
methadone hydrochloride |
NICE TA114 |
||||
Methadone
INJECTION IS HOSPITAL ONLY |
|||||
Oral solution | |||||
Methadone hydrochloride (Non-proprietary) | |||||
Drug Misuse-Methadone and Buprenorphine
NICE TA114 |
|||||
Methadose (Rosemont Pharmaceuticals Ltd) | |||||
Metharose (Rosemont Pharmaceuticals Ltd) | |||||
Physeptone (Martindale Pharmaceuticals Ltd) | |||||
Solution for injection | |||||
Methadone hydrochloride (Non-proprietary) | |||||
Drug Misuse-Methadone and Buprenorphine
NICE TA114 |
|||||
Oral tablet | |||||
Methadone hydrochloride (Non-proprietary) | |||||
morphine | On Formulary | ||||
Prescribing in Palliative Care
Palliative Care Team Contacts:
|
|||||
Orodispersible tablet | |||||
Actimorph (Ethypharm UK Ltd) | |||||
Modified-release tablet | |||||
MST Continus (Napp Pharmaceuticals Ltd) | |||||
Morphgesic SR (Advanz Pharma) | |||||
Modified-release capsule | |||||
MXL (Napp Pharmaceuticals Ltd) | |||||
Zomorph (Ethypharm UK Ltd) | |||||
Oral solution | |||||
Morphine (Non-proprietary) | |||||
Oramorph (Glenwood GmbH) | |||||
Solution for injection | |||||
Morphine (Non-proprietary) | |||||
Prescribing in Palliative Care
http://bartshealthintranet/About-Us/CAGs/Cancer/Palliative-care/Index.aspx
|
|||||
Infusion | |||||
Morphine (Non-proprietary) | |||||
Solution for infusion | |||||
Morphine (Non-proprietary) | |||||
Prescribing in Palliative Care
http://bartshealthintranet/About-Us/CAGs/Cancer/Palliative-care/Index.aspx
|
|||||
Oral tablet | |||||
Sevredol (Napp Pharmaceuticals Ltd) | |||||
Respiratory system / Allergic conditions | |||||
acrivastine | Off Formulary | ||||
Oral capsule | |||||
Acrivastine (Non-proprietary) | |||||
Benadryl Allergy Relief (McNeil Products Ltd) | |||||
alimemazine tartrate | Off Formulary | ||||
Oral solution | |||||
Alimemazine tartrate (Non-proprietary) | |||||
Alfresed (Syri Ltd) | |||||
Itzenal (Zentiva Pharma UK Ltd) | |||||
Oral tablet | |||||
Alimemazine tartrate (Non-proprietary) | |||||
bee venom extract | Hospital Only |
NICE TA246 |
|||
Bee Venom Kits
These immunotherapies are to be managed only by the Bart's Allergy Specialist center. |
|||||
bilastine | Off Formulary | ||||
Oral tablet | |||||
Ilaxten (A. Menarini Farmaceutica Internazionale SRL) | |||||
cetirizine hydrochloride | On Formulary | ||||
Oral solution | |||||
Cetirizine hydrochloride (Non-proprietary) | On Formulary | ||||
Oral tablet | |||||
Cetirizine hydrochloride (Non-proprietary) | |||||
chlorphenamine maleate | On Formulary | ||||
Oral solution | |||||
Chlorphenamine maleate (Non-proprietary) | On Formulary | ||||
Allergic Rhinitis Pathway
see attached |
|||||
Allerief (Crescent Pharma Ltd) | |||||
Piriton (Haleon UK Trading Ltd) | |||||
Allergic Rhinitis Pathway
see attached |
|||||
Solution for injection | |||||
Chlorphenamine maleate (Non-proprietary) | On Formulary | ||||
Oral tablet | |||||
Chlorphenamine maleate (Non-proprietary) | |||||
Allerief (Crescent Pharma Ltd) | |||||
Hayleve (Genesis Pharmaceuticals Ltd) | |||||
Piriton (Haleon UK Trading Ltd) | |||||
cyproheptadine hydrochloride | Hospital Only | ||||
Oral tablet | |||||
Periactin (Teva UK Ltd) | |||||
desloratadine | Off Formulary | ||||
Oral solution | |||||
Desloratadine (Non-proprietary) | |||||
Neoclarityn (Organon Pharma (UK) Ltd) | |||||
Oral tablet | |||||
Desloratadine (Non-proprietary) | |||||
Neoclarityn (Organon Pharma (UK) Ltd) | |||||
fexofenadine hydrochloride | On Formulary | ||||
Oral tablet | |||||
Fexofenadine hydrochloride (Non-proprietary) | |||||
Telfast (Sanofi Consumer Healthcare) | |||||
grass pollen extract | On Formulary | ||||
GRASS AND TREE POLLEN EXTRACTS
THIS IS A HOSPITAL ONLY DRUG and to be used only by the Bart's specialist Allergy Team |
|||||
Oral lyophilisate | |||||
Grazax (ALK-Abello Ltd) | Hospital Only | ||||
Form unstated | |||||
Pollinex Grasses + Rye (Allergy Therapeutics (UK) Ltd) | Hospital Only | ||||
house dust mite extract | |||||
Acarizax as an option for house dust mite allergic rhinitis
Approved across NEL December 2022 |
|||||
Oral lyophilisate | |||||
Acarizax (ALK-Abello Ltd) | On Formulary | ||||
hydroxyzine hydrochloride | On Formulary | ||||
Oral tablet | |||||
Hydroxyzine hydrochloride (Non-proprietary) | |||||
ketotifen | Off Formulary | ||||
Oral solution | |||||
Zaditen (CD Pharma Srl) | |||||
Eye drops | |||||
Ketofall (Scope Ophthalmics Ltd) | |||||
Zaditen (Thea Pharmaceuticals Ltd) | |||||
Oral tablet | |||||
Zaditen (CD Pharma Srl) | |||||
levocetirizine hydrochloride | Off Formulary | ||||
Oral solution | |||||
Xyzal (UCB Pharma Ltd) | |||||
Oral tablet | |||||
Levocetirizine hydrochloride (Non-proprietary) | |||||
Xyzal (UCB Pharma Ltd) | |||||
loratadine | On Formulary | ||||
Oral solution | |||||
Loratadine (Non-proprietary) | On Formulary | ||||
Allergic Rhinitis Pathway
see attached |
|||||
Oral tablet | |||||
Loratadine (Non-proprietary) | |||||
mizolastine | Off Formulary | ||||
Modified-release tablet | |||||
Mizollen (Sanofi Consumer Healthcare) | |||||
peanut protein | |||||
NICE TA 769 - June 2023 - Palforzia for treating peanut allergy in children and young people
Palforzia approved at NEL FPG for treating peanut allergy in children and young people in line with NICE TA 769. First published Feb 2022, updated 2023. HCD from April 2023 (Blueteq forms to be completed)
|
|||||
Form unstated | |||||
Palforzia (Stallergenes Greer Ltd) | |||||
Oral powder | |||||
Palforzia (Stallergenes Greer Ltd) | |||||
promethazine hydrochloride | On Formulary | ||||
PROMETHAZINE HYDROCHLORIDE
INJECTION IS HOSPITAL ONLY |
|||||
Oral solution | |||||
Phenergan (Sanofi Consumer Healthcare) | |||||
Solution for injection | |||||
Phenergan (Sanofi Consumer Healthcare) | On Formulary | ||||
PROMETHAZINE HYDROCHLORIDE
INJECTION IS HOSPITAL ONLY |
|||||
Rapid Tranquilisation Trust Policy Barts Health
see attached |
|||||
Oral tablet | |||||
Promethazine hydrochloride (Non-proprietary) | |||||
Phenergan (Sanofi Consumer Healthcare) | |||||
Sominex (Dexcel-Pharma Ltd) | |||||
rupatadine | Off Formulary | ||||
Oral tablet | |||||
Rupatadine (Non-proprietary) | |||||
tree pollen extract | Hospital Only | ||||
Tree Pollen
To be used only by the Bart's Specialist Allergy Team |
|||||
Suspension for injection | |||||
Pollinex Trees (Allergy Therapeutics (UK) Ltd) | |||||
Form unstated | |||||
Pollinex Trees (Allergy Therapeutics (UK) Ltd) | |||||
wasp venom extract | Hospital Only |
NICE TA246 |
|||
Wasp Venom
To be used only by Bart's Specialist Allergy team |
|||||
Respiratory system / Anaphylaxis | |||||
adrenaline/epinephrine | On Formulary | ||||
RLH Adult ENT A&E guidelines 2015
see attached |
|||||
MHRA Alert Oct 2019
The Medicines & Healthcare products Regulatory Agency (MHRA) has received reports of Emerade pens failing to activate. The product is not being recalled, instead the attached patient information should be given to patients who use this product. Further information on the alert can be found: https://www.gov.uk/drug-device-alerts/class-4-medicines-defect-information-emerade-150-300-and-500-microgram-solution-for-injection-in-pre-filled-syringe-mdr-57-08-19?utm_source=f03b2ee9-32c9-4c29-9dde-a224560325d3&utm_medium=email&utm_campaign=govuk-notifications&utm_content=immediate Patients experiencing any problem with Emerade failing to activate should report this via the MHRA’s Yellow Card Scheme and keep the pen for further examination. |
|||||
Adrenaline auto-injector shortage
There is an on-going supply issue with Emerade devices, which is affecting the stock of all other brands of adrenaline auto-injectors.
Please refer to the below memo for further information. |
|||||
Solution for injection | |||||
Adrenaline/epinephrine (Non-proprietary) | On Formulary | ||||
EpiPen (Viatris UK Healthcare Ltd) | On Formulary | ||||
Jext (ALK-Abello Ltd) | On Formulary | ||||
chlorphenamine maleate | On Formulary | ||||
Oral solution | |||||
Chlorphenamine maleate (Non-proprietary) | On Formulary | ||||
Allerief (Crescent Pharma Ltd) | |||||
Piriton (Haleon UK Trading Ltd) | |||||
Solution for injection | |||||
Chlorphenamine maleate (Non-proprietary) | On Formulary | ||||
Oral tablet | |||||
Chlorphenamine maleate (Non-proprietary) | |||||
Allerief (Crescent Pharma Ltd) | |||||
Hayleve (Genesis Pharmaceuticals Ltd) | |||||
Piriton (Haleon UK Trading Ltd) | |||||
Respiratory system / Angioedema | |||||
C1-esterase inhibitor | Hospital Only | ||||
Powder and solvent for solution for injection | |||||
Berinert P (CSL Behring UK Ltd) | On Formulary | ||||
Hereditary Angioedema
|
|||||
Hereditary Angioedema
|
|||||
Berinert®
Contact Hilary Longhurst for advice and prescribing |
|||||
Cinryze (Takeda UK Ltd) | |||||
berotralstat |
NICE TA738 |
||||
Oral capsule | |||||
Orladeyo (BioCryst Ireland Ltd) | |||||
conestat alfa | On Formulary | ||||
Powder for solution for injection | |||||
Ruconest (Pharming Group N.V.) | On Formulary | ||||
Powder and solvent for solution for injection | |||||
Ruconest (Pharming Group N.V.) | |||||
icatibant | On Formulary | ||||
ICATIBANT
FOR HOSPITAL USE ONLY |
|||||
Icatabant for the treatment of hereditary angioedema (HAE), November 2008
The Group recommended the use of icatabant to treat hereditary angioedema (HAE) as an alternative to an IV infusion of C1 esterase inhibitor (CIC) in adults where:
|
|||||
Solution for injection | |||||
Icatibant (Non-proprietary) | |||||
Firazyr (Takeda UK Ltd) | On Formulary | ||||
Firazyr®
FOR HOSPITAL USE ONLY |
|||||
lanadelumab | On Formulary |
NICE TA606 |
|||
Solution for injection | |||||
Lanadelumab (Non-proprietary) | |||||
Takhzyro (Takeda UK Ltd) | |||||
Respiratory system / Conditions affecting sputum viscosity | |||||
acetylcysteine | On Formulary | ||||
Effervescent tablet | |||||
Acetylcysteine (Non-proprietary) | |||||
A-CYS (Ennogen Healthcare Ltd) | |||||
AceCil (Essential-Healthcare Ltd) | |||||
Acepiro (Stirling Anglian Pharmaceuticals Ltd) | |||||
NACSYS (Alturix Ltd) | |||||
Solution for infusion | |||||
Acetylcysteine (Non-proprietary) | |||||
Parvolex (Phoenix Labs Ltd) | |||||
Eye drops | |||||
Ilube (Rayner Pharmaceuticals Ltd) | Off Formulary | ||||
carbocisteine | On Formulary | ||||
Oral solution | |||||
Carbocisteine (Non-proprietary) | On Formulary | ||||
Mucodyne (Sanofi) | On Formulary | ||||
Oral capsule | |||||
Carbocisteine (Non-proprietary) | |||||
erdosteine | Off Formulary | ||||
Oral capsule | |||||
Erdotin (Galen Ltd) | |||||
Respiratory system / Cystic fibrosis | |||||
dornase alfa | Hospital Only | ||||
DORNASE ALFA
Prevention of mucus plugging and deterioration of lung function in Cystic Fibrosis NHSE commissioned. Mainly supplied via Homecare for ongoing supplies at home. |
|||||
Nebuliser liquid | |||||
Pulmozyme (Roche Products Ltd) | |||||
ivacaftor | Hospital Only | ||||
IVACAFTOR
FOR HOSPITAL USE ONLY |
|||||
Oral tablet | |||||
Kalydeco (Vertex Pharmaceuticals (Europe) Ltd) | |||||
ivacaftor with tezacaftor and elexacaftor |
NICE TA988 |
||||
Oral tablet | |||||
Kaftrio (Vertex Pharmaceuticals (Europe) Ltd) | |||||
lumacaftor with ivacaftor | Hospital Only |
NICE TA398 |
|||
Orkambi
Compassionate Supply via Vertex for patient that meet criteria.
|
|||||
Oral tablet | |||||
Orkambi (Vertex Pharmaceuticals (Europe) Ltd) | |||||
mannitol | On Formulary |
NICE TA266 |
|||
Osmohale Inhalation Powde (Mannitol) challenge to diagnose bronchial hyper-responsiveness (February 2023)
Mannitol was approved at NEL FPG as a third line option to histamine for aiding the diagnosis of bronchial hyper-responsiveness in adults where other diagnostics had been inconclusive, as an indirect challenge test. |
|||||
Infusion | |||||
Mannitol (Non-proprietary) | |||||
Inhalation powder | |||||
Mannitol (Non-proprietary) | |||||
Bronchitol (Chiesi Ltd) | |||||
tezacaftor with ivacaftor | On Formulary |
NICE TA988 |
|||
Oral tablet | |||||
Symkevi (Vertex Pharmaceuticals (Europe) Ltd) | |||||
Respiratory system / Interstitial lung disease | |||||
nintedanib |
NICE TA347 NICE TA379 NICE TA864 NICE TA747 |
||||
Oral capsule | |||||
Ofev (Boehringer Ingelheim Ltd) | |||||
Vargatef (Boehringer Ingelheim Ltd) | |||||
pirfenidone |
NICE TA504 |
||||
Oral tablet | |||||
Pirfenidone (Non-proprietary) | |||||
Esbriet (Roche Products Ltd) |