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Malignant disease
Malignant disease / Antibody responsive malignancy
  amivantamab [Specialist drug] NICE TA850
  Solution for infusion
Rybrevant (Janssen-Cilag Ltd)
  atezolizumab [Specialist drug] Hospital Only NICE TA525
NICE TA739
NICE TA520
NICE TA584
NICE TA705
NICE TA823
NICE TA638
NICE TA639
NICE TA666
  Solution for infusion
Tecentriq (Roche Products Ltd)
  avelumab [Specialist drug] Hospital Only NICE TA517
NICE TA691
NICE TA645
NICE TA788
  Solution for infusion
Bavencio (Merck Serono Ltd)
  belantamab mafodotin [Specialist drug]
  Powder for solution for infusion
Blenrep (GlaxoSmithKline UK Ltd)
  bevacizumab [Specialist drug] Hospital Only NICE TA118
NICE TA212
NICE TA242
NICE TA178
NICE TA214
NICE TA263
NICE TA284
NICE TA285
NICE TA666
NICE TA946
Bevacizumab

HOSPITAL ONLY 
UNLICENSED

  1. For the treatment of rubeotic glaucoma where there is an intraocular pressure >28mm Hg secondary to iris rubeosis, where pan-retinal laser treatment has been ineffective. All prescribing and administration will be carried out by a consultant ophthalmologist specialised in the management of this condition.
  2. The drug will be stopped if there is regression of iris rubeosis, and an intraocular pressure of <21mm Hg (on topical therapy), or an assessment of clinically inactive iris rubeosis.
  3. As the drug is both unlicensed in this condition and supplied as a formulation for intravitreal injection from a specials unit, the patient must be educated on the use of the medication and consent documented in the patient record.
  4. The cost of drug, supplied as 1.25mg in 0.05ml, will be funded by the Ophthalmology Department as the cost is sufficiently covered within the tariff charged for an injection in outpatients.
  5. As the drug is ordered in specially, the dose must be requested in good time. Please liaise with Kamini Patel at Whipps Cross to organise this to avoid any problems with doses not being ready.
  6. The patient numbers are estimated to be around 3-5 per annum.

  Solution for infusion
Alymsys (Zentiva Pharma UK Ltd)
Avastin (Roche Products Ltd) On Formulary
Bevacizumab

HOSPITAL ONLY 
UNLICENSED

  1. For the treatment of rubeotic glaucoma where there is an intraocular pressure >28mm Hg secondary to iris rubeosis, where pan-retinal laser treatment has been ineffective. All prescribing and administration will be carried out by a consultant ophthalmologist specialised in the management of this condition.
  2. The drug will be stopped if there is regression of iris rubeosis, and an intraocular pressure of <21mm Hg (on topical therapy), or an assessment of clinically inactive iris rubeosis.
  3. As the drug is both unlicensed in this condition and supplied as a formulation for intravitreal injection from a specials unit, the patient must be educated on the use of the medication and consent documented in the patient record.
  4. The cost of drug, supplied as 1.25mg in 0.05ml, will be funded by the Ophthalmology Department as the cost is sufficiently covered within the tariff charged for an injection in outpatients.
  5. As the drug is ordered in specially, the dose must be requested in good time. Please liaise with Kamini Patel at Whipps Cross to organise this to avoid any problems with doses not being ready.
  6. The patient numbers are estimated to be around 3-5 per annum.

Avastin®

To be sourced from Royal Free for patients with rubeotic glaucoma (elective treatment)

Aybintio (Organon Pharma (UK) Ltd)
Oyavas (Thornton & Ross Ltd)
Vegzelma (Celltrion Healthcare UK Ltd)
Versavo (Dr Reddy's Laboratories (UK) Ltd)
Zirabev (Pfizer Ltd)
  blinatumomab [Specialist drug] Hospital Only NICE TA450
NICE TA589
  Powder for solution for infusion
Blincyto (Amgen Ltd)
  brentuximab vedotin [Specialist drug] Hospital Only NICE TA478
NICE TA641
NICE TA524
NICE TA577
  Powder for solution for infusion
Adcetris (Takeda UK Ltd)
  cemiplimab [Specialist drug] NICE TA802
  Solution for infusion
Libtayo (Regeneron UK Ltd)
  cetuximab [Specialist drug] Hospital Only NICE TA145
NICE TA473
NICE TA242
NICE TA439
NICE TA668
  Solution for infusion
Erbitux (Merck Serono Ltd) On Formulary
Cetuximab prescribing

Erbitux®

For large bowel cancers

  daratumumab Hospital Only NICE TA763
NICE TA783
NICE TA897
NICE TA917
NICE TA959
  Solution for injection
Darzalex (Janssen-Cilag Ltd)
  Solution for infusion
Darzalex (Janssen-Cilag Ltd)
  dinutuximab beta [Specialist drug] Off Formulary NICE TA538
  Solution for infusion
Qarziba (Recordati UK Ltd)
  dostarlimab [Specialist drug] NICE TA779
NICE TA963
  Solution for infusion
Jemperli (GlaxoSmithKline UK Ltd)
  durvalumab [Specialist drug] Hospital Only NICE TA798
NICE TA944
  Solution for infusion
Imfinzi (AstraZeneca UK Ltd)
  elotuzumab [Specialist drug] Off Formulary
  Powder for solution for infusion
Empliciti (Bristol-Myers Squibb Pharmaceuticals Ltd)
  elranatamab [Specialist drug]
  Solution for injection
Elrexfio (Pfizer Ltd)
  enfortumab vedotin [Specialist drug]
  Powder for solution for infusion
Padcev (Astellas Pharma Ltd)
  epcoritamab [Specialist drug] NICE TA954
  Solution for injection
Tepkinly (AbbVie Ltd)
  gemtuzumab ozogamicin [Specialist drug] Hospital Only NICE TA545
  Powder for solution for infusion
Mylotarg (Pfizer Ltd)
  glofitamab [Specialist drug] NICE TA927
  Solution for infusion
Columvi (Roche Products Ltd)
  inotuzumab ozogamicin [Specialist drug] Hospital Only NICE TA541
  Powder for solution for infusion
Besponsa (Pfizer Ltd)
  ipilimumab [Specialist drug] Hospital Only NICE TA268
NICE TA319
NICE TA400
NICE TA716
NICE TA724
NICE TA780
NICE TA818
  Solution for infusion
Yervoy (Bristol-Myers Squibb Pharmaceuticals Ltd)
  isatuximab [Specialist drug] Hospital Only NICE TA658
Approved by Cancer DTC

December 2020

  Solution for infusion
Sarclisa (Sanofi)
  loncastuximab tesirine [Specialist drug] NICE TA947
  Powder for solution for infusion
Zynlonta (Swedish Orphan Biovitrum Ltd)
  mogamulizumab [Specialist drug] NICE TA754
NICE TA754
  Solution for infusion
Poteligeo (Kyowa Kirin Ltd)
  mosunetuzumab [Specialist drug] NICE TA892
  Solution for infusion
Lunsumio (Roche Products Ltd)
  nivolumab [Specialist drug] Hospital Only NICE TA384
NICE TA400
NICE TA684
NICE TA417
NICE TA780
NICE TA964
NICE TA462
NICE TA655
NICE TA713
NICE TA724
NICE TA876
NICE TA530
NICE TA817
NICE TA707
NICE TA746
NICE TA857
NICE TA865
NICE TA716
NICE TA736
NICE TA818
  Solution for infusion
Opdivo (Bristol-Myers Squibb Pharmaceuticals Ltd)
  nivolumab with relatlimab [Specialist drug] NICE TA950
  Solution for infusion
Opdualag (Bristol-Myers Squibb Pharmaceuticals Ltd)
  obinutuzumab [Specialist drug] Hospital Only NICE TA343
NICE TA513
NICE TA629
  Solution for infusion
Gazyvaro (Roche Products Ltd)
  panitumumab [Specialist drug] Hospital Only NICE TA242
NICE TA439
  Solution for infusion
Vectibix (Amgen Ltd)
  pembrolizumab [Specialist drug] Hospital Only NICE TA357
NICE TA366
NICE TA766
NICE TA837
NICE TA428
NICE TA531
NICE TA683
NICE TA770
NICE TA692
NICE TA772
NICE TA540
NICE TA967
NICE TA650
NICE TA830
NICE TA858
NICE TA661
NICE TA709
NICE TA914
NICE TA983
NICE TA737
NICE TA997
NICE TA801
NICE TA851
NICE TA939
NICE TA904
  Solution for infusion
Keytruda (Merck Sharp & Dohme (UK) Ltd)
  pertuzumab [Specialist drug] Hospital Only NICE TA424
NICE TA509
NICE TA569
  Solution for infusion
Perjeta (Roche Products Ltd)
  pertuzumab with trastuzumab [Specialist drug]
  Solution for injection
Phesgo (Roche Products Ltd)
  polatuzumab vedotin [Specialist drug] Hospital Only NICE TA649
NICE TA874
Approved by Cancer DTC

November 2020

  Powder for solution for infusion
Polivy (Roche Products Ltd)
  ramucirumab [Specialist drug] Hospital Only NICE TA378
NICE TA403
  Solution for infusion
Cyramza (Eli Lilly and Company Ltd)
  rituximab Hospital Only NICE TA308
NICE TA195
NICE TA243
NICE TA137
NICE TA193
NICE TA226
NICE TA174
NICE TA359
NICE TA561
Rituximab-Connective Tissue Disease and Hypersensitivity Pneumonitis - Interstitial Lung Disease (CTD-ILD and HP-ILD) (November-2022)

NEL FPG Approved for use in Connective Tissue Disease- Interstitial Lung Disease (CTD-ILD) and Hypersensitivity Pneumonitis- Interstitial Lung Disease (HP-ILD)

Treatment of Interstitial Lung Disease (ILD) in patients with severe active disease that has failed to respond to, or patient is intolerant to at least 2 immunosuppressants (tacrolimus, methotrexate, mycophenolate or cyclophosphamide), each having been taken for at least 3 months.

Rituximab IV 1g on day 1 and day 15, then repeated 6 monthly if the patient responds.

Hospital Only

RENAL SERVICE

On Formulary for Idiopathic Membraneous Glomerulonephritis,

biopsy-proven, steroid-sensitive minimal change nephropathy or primary focal segmental glomerulosclerosis (non-commissioned).

 

Renal Transplant Patients

For vasculitis in renal transplant 
As immunuppression for ABO incompatible transplants

 

Rituximab use in clinical haematology indications

Truxima brand is used in clinical haematology indications. 

Rituximab for the treatment of IgM paraproteinaemic demyelinating peripheral neuropathy in adult

Rituximab for the treatment of IgM paraproteinaemic demyelinating peripheral neuropathy in adults approved for use in May 2022 DTC as per Clinical Commissioning policy SSC2319

  Solution for injection
MabThera (Roche Products Ltd)
  Solution for infusion
MabThera (Roche Products Ltd) Hospital Only
Rixathon (Sandoz Ltd)
Ruxience (Pfizer Ltd)
Truxima (Celltrion Healthcare UK Ltd)
  sacituzumab govitecan [Specialist drug] NICE TA819
  Powder for solution for infusion
Trodelvy (Gilead Sciences Ltd)
  siltuximab Off Formulary
  Powder for solution for infusion
Sylvant (Recordati UK Ltd)
  tafasitamab [Specialist drug] NICE TA883
  Powder for solution for infusion
Minjuvi (Incyte Biosciences UK Ltd)
  talquetamab [Specialist drug]
  Solution for injection
Talvey (Janssen-Cilag Ltd)
  teclistamab [Specialist drug]
  Solution for injection
Tecvayli (Janssen-Cilag Ltd)
  trastuzumab [Specialist drug] Hospital Only NICE TA34
NICE TA257
NICE TA509
NICE TA208
Trastuzumab subcutaneous

trastuzumab

  Solution for injection
Herceptin (Roche Products Ltd) On Formulary
Trastuzumab subcutaneous

see attached

  Powder for solution for infusion
Herceptin (Roche Products Ltd)
Herzuma (Celltrion Healthcare UK Ltd)
Ontruzant (Organon Pharma (UK) Ltd)
Trazimera (Pfizer Ltd)
Zercepac (Accord-UK Ltd)
  trastuzumab deruxtecan [Specialist drug] NICE TA704
NICE TA862
NICE TA992
  Powder for solution for infusion
Enhertu (Daiichi Sankyo UK Ltd)
  trastuzumab emtansine [Specialist drug] Hospital Only NICE TA458
NICE TA632
  Powder for solution for infusion
Kadcyla (Roche Products Ltd)
  tremelimumab [Specialist drug]
  Solution for infusion
Imjudo (AstraZeneca UK Ltd)
Malignant disease / Carcinoid syndrome
  telotristat ethyl Off Formulary
  Oral tablet
Xermelo (SERB)
Malignant disease / Immunotherapy responsive malignancy
  Bacillus Calmette-Guérin [Specialist drug] Hospital Only
  Powder for reconstitution for instillation
OncoTICE (Merck Sharp & Dohme (UK) Ltd) On Formulary
  Powder and solvent for intravesical suspension
BCG-medac (medac UK)
  aldesleukin [Specialist drug] Hospital Only
ALDESLEUKIN

HOSPITAL ONLY

  Powder for solution for injection
Proleukin (Clinigen Healthcare Ltd) Hospital Only
  interferon gamma-1b Off Formulary
  Solution for injection
Immukin (Clinigen Healthcare Ltd)
  lenalidomide [Specialist drug] Hospital Only NICE TA322
NICE TA171
NICE TA586
NICE TA587
NICE TA627
NICE TA680
Lenalidomide/Pomalidomide/Thalidomide Prescribing

see attached

  Oral capsule
Lenalidomide (Non-proprietary)
Revlimid (Bristol-Myers Squibb Pharmaceuticals Ltd)
  mifamurtide [Specialist drug] Off Formulary NICE TA235
  pomalidomide [Specialist drug] Hospital Only NICE TA427
Lenalidomide/Pomalidomide/Thalidomide Prescribing

see attached

  Oral capsule
Imnovid (Bristol-Myers Squibb Pharmaceuticals Ltd)
  talimogene laherparepvec [Specialist drug] Hospital Only NICE TA410
  Solution for injection
Imlygic (Amgen Ltd)
  thalidomide [Specialist drug] Hospital Only NICE TA228
Lenalidomide/Pomalidomide/Thalidomide Prescribing

see attached

  Oral tablet
Talidex (Special Order)
  Oral capsule
Thalidomide (Non-proprietary)
Malignant disease / Targeted therapy responsive malignancy
  abemaciclib [Specialist drug] Hospital Only NICE TA563
NICE TA725
NICE TA810
  Oral tablet
Verzenios (Eli Lilly and Company Ltd)
  acalabrutinib [Specialist drug] NICE TA689
NICE TA689
  Oral tablet
Calquence (AstraZeneca UK Ltd)
  afatinib [Specialist drug] Hospital Only NICE TA310
  Oral tablet
Giotrif (Boehringer Ingelheim Ltd)
  aflibercept [Specialist drug] Hospital Only NICE TA294
NICE TA305
NICE TA346
NICE TA409
NICE TA486
NICE TA307
  Solution for injection
Eylea (Bayer Plc) Hospital Only
  Solution for infusion
Zaltrap (Sanofi) Hospital Only
  alectinib [Specialist drug] Hospital Only NICE TA536
  Oral capsule
Alecensa (Roche Products Ltd)
  alpelisib [Specialist drug] NICE TA816
  Oral tablet
Piqray (Novartis Pharmaceuticals UK Ltd)
  asciminib [Specialist drug] NICE TA813
  Oral tablet
Scemblix (Novartis Pharmaceuticals UK Ltd)
  avapritinib [Specialist drug]
  Oral tablet
Ayvakyt (Blueprint Medicines (UK) Ltd)
  axitinib [Specialist drug] Hospital Only NICE TA333
NICE TA645
NICE TA650
  Oral tablet
Inlyta (Pfizer Ltd)
  belzutifan [Specialist drug]
  Oral tablet
Welireg (Merck Sharp & Dohme (UK) Ltd)
  binimetinib [Specialist drug] Hospital Only NICE TA562
  Oral tablet
Mektovi (Pierre Fabre Ltd)
  bortezomib [Specialist drug] Hospital Only NICE TA370
NICE TA311
NICE TA228
NICE TA129
  Solution for injection
Bortezomib (Non-proprietary)
  Powder for solution for injection
Bortezomib (Non-proprietary)
Velcade (Janssen-Cilag Ltd) On Formulary
  bosutinib [Specialist drug] Hospital Only NICE TA401
  Oral tablet
Bosulif (Pfizer Ltd)
  brigatinib [Specialist drug] Hospital Only NICE TA571
NICE TA670
  Form unstated
Alunbrig (Takeda UK Ltd)
  Oral tablet
Alunbrig (Takeda UK Ltd)
  cabozantinib [Specialist drug] Hospital Only NICE TA463
NICE TA542
NICE TA964
NICE TA516
NICE TA928
NICE TA849
  Form unstated
Cometriq (Ipsen Ltd)
  Oral tablet
Cabometyx (Ipsen Ltd)
  Oral capsule
Cometriq (Ipsen Ltd)
  carfilzomib [Specialist drug] Hospital Only NICE TA657
NICE TA695
  Powder for solution for infusion
Kyprolis (Amgen Ltd)
  ceritinib [Specialist drug] Hospital Only NICE TA395
NICE TA500
  Oral tablet
Zykadia (Novartis Pharmaceuticals UK Ltd)
  cobimetinib [Specialist drug] Hospital Only NICE TA414
  Oral tablet
Cotellic (Roche Products Ltd)
  crizotinib [Specialist drug] Hospital Only NICE TA406
NICE TA422
NICE TA529
  Oral capsule
Xalkori (Pfizer Ltd)
  dabrafenib [Specialist drug] Hospital Only NICE TA321
NICE TA396
NICE TA544
NICE TA898
  Oral capsule
Tafinlar (Novartis Pharmaceuticals UK Ltd)
  dacomitinib [Specialist drug] NICE TA595
  Oral tablet
Vizimpro (Pfizer Ltd)
  dasatinib [Specialist drug] Hospital Only NICE TA426
NICE TA425
  Oral suspension
Sprycel (Imported (Germany))
  Oral tablet
Dasatinib (Non-proprietary)
Sprycel (Bristol-Myers Squibb Pharmaceuticals Ltd)
  encorafenib [Specialist drug] Hospital Only NICE TA562
NICE TA668
  Oral capsule
Braftovi (Pierre Fabre Ltd)
  entrectinib [Specialist drug] NICE TA643
NICE TA644
  Oral capsule
Rozlytrek (Roche Products Ltd)
  erlotinib [Specialist drug] Hospital Only NICE TA227
NICE TA258
NICE TA374
NICE TA374
  Oral tablet
Erlotinib (Non-proprietary)
Tarceva (Roche Products Ltd)
  everolimus Hospital Only NICE TA421
NICE TA432
NICE TA449
Afinitor® NICE TA498
Certican® NICE TA348
Certican® NICE TA481
  Dispersible tablet
Votubia (Novartis Pharmaceuticals UK Ltd)
  Oral tablet
Everolimus (Non-proprietary)
Afinitor (Novartis Pharmaceuticals UK Ltd)
Certican (Novartis Pharmaceuticals UK Ltd)
Votubia (Novartis Pharmaceuticals UK Ltd)
  fedratinib [Specialist drug] NICE TA756
  Oral capsule
Inrebic (Bristol-Myers Squibb Pharmaceuticals Ltd)
  gefitinib [Specialist drug] Hospital Only NICE TA192
NICE TA374
  Oral tablet
Gefitinib (Non-proprietary)
Iressa (AstraZeneca UK Ltd)
  gilteritinib [Specialist drug] NICE TA642
  Oral tablet
Xospata (Astellas Pharma Ltd)
  glasdegib [Specialist drug]
  Oral tablet
Daurismo (Pfizer Ltd)
  ibrutinib [Specialist drug] Hospital Only NICE TA429
NICE TA891
NICE TA502
NICE TA795
  Oral tablet
Imbruvica (Janssen-Cilag Ltd)
  idelalisib [Specialist drug] Hospital Only NICE TA359
NICE TA604
  Oral tablet
Zydelig (Gilead Sciences Ltd)
  imatinib [Specialist drug] Hospital Only NICE TA326
NICE TA70
NICE TA86
NICE TA209
NICE TA426
NICE TA425
  Oral tablet
Imatinib (Non-proprietary)
Glivec (Novartis Pharmaceuticals UK Ltd)
  ivosidenib [Specialist drug] NICE TA948
NICE TA979
  Oral tablet
Tibsovo (Servier Laboratories Ltd)
  ixazomib [Specialist drug] Hospital Only NICE TA870
  Oral capsule
Ninlaro (Takeda UK Ltd)
  lapatinib [Specialist drug] Off Formulary NICE TA257
LAPATINIB

Please note: This medicine is HOSPITAL ONLY.

  Oral tablet
Tyverb (Novartis Pharmaceuticals UK Ltd)
  larotrectinib [Specialist drug] NICE TA630
  Oral solution
Vitrakvi (Bayer Plc)
  Oral capsule
Vitrakvi (Bayer Plc)
  lenvatinib [Specialist drug] Hospital Only NICE TA535
NICE TA551
NICE TA498
NICE TA858
NICE TA904
  Oral capsule
Kisplyx (Eisai Ltd)
Lenvima (Eisai Ltd)
  lorlatinib [Specialist drug] NICE TA628
NICE TA909
  Oral tablet
Lorviqua (Pfizer Ltd)
  midostaurin [Specialist drug] Hospital Only NICE TA523
NICE TA728
  Oral capsule
Rydapt (Novartis Pharmaceuticals UK Ltd)
  mobocertinib [Specialist drug] NICE TA855
  momelotinib [Specialist drug] NICE TA957
  Oral tablet
Omjjara (GlaxoSmithKline UK Ltd)
  neratinib [Specialist drug] NICE TA612
  Oral tablet
Nerlynx (Pierre Fabre Ltd)
  nilotinib [Specialist drug] Hospital Only NICE TA426
NICE TA425
  Oral capsule
Tasigna (Novartis Pharmaceuticals UK Ltd)
  nintedanib Hospital Only NICE TA347
NICE TA379
NICE TA864
NICE TA747
Nintedanib for use in IPF

This can only be initiated by a specialist IPF center.

Barts health is not commissioned as a IPF center by NHSE.

  Oral capsule
Ofev (Boehringer Ingelheim Ltd)
Vargatef (Boehringer Ingelheim Ltd)
  niraparib [Specialist drug] Hospital Only NICE TA673
NICE TA784
  Oral capsule
Zejula (GlaxoSmithKline UK Ltd)
  olaparib [Specialist drug] Hospital Only NICE TA908
NICE TA946
NICE TA962
NICE TA886
NICE TA887
NICE TA951
  Oral tablet
Lynparza (AstraZeneca UK Ltd)
  osimertinib [Specialist drug] Hospital Only NICE TA653
NICE TA654
NICE TA761
  Oral tablet
Tagrisso (AstraZeneca UK Ltd)
  palbociclib [Specialist drug] Hospital Only NICE TA495
NICE TA836
  Oral tablet
Ibrance (Pfizer Ltd)
  pazopanib [Specialist drug] Hospital Only NICE TA215
  Oral tablet
Votrient (Novartis Pharmaceuticals UK Ltd)
  pemigatinib [Specialist drug] NICE TA722
  Oral tablet
Pemazyre (Incyte Biosciences UK Ltd)
  ponatinib [Specialist drug] Hospital Only NICE TA451
  Oral tablet
Ponatinib (Non-proprietary)
  pralsetinib [Specialist drug] NICE TA812
  Oral capsule
Gavreto (Roche Products Ltd)
  quizartinib [Specialist drug]
  Oral tablet
Vanflyta (Daiichi Sankyo UK Ltd)
  regorafenib [Specialist drug] Hospital Only NICE TA488
NICE TA555
NICE TA866
  Oral tablet
Stivarga (Bayer Plc)
  ribociclib [Specialist drug] Hospital Only NICE TA496
NICE TA687
  Oral tablet
Kisqali (Novartis Pharmaceuticals UK Ltd)
  ripretinib [Specialist drug] NICE TA881
  Oral tablet
Qinlock (Deciphera Pharmaceuticals (Netherlands) B.V.)
  rucaparib [Specialist drug] Hospital Only NICE TA611
  Oral tablet
Rubraca (pharmaand GmbH)
  ruxolitinib [Specialist drug] Hospital Only NICE TA386
NICE TA921
  Oral tablet
Jakavi (Novartis Pharmaceuticals UK Ltd)
  selinexor [Specialist drug] NICE TA970
NICE TA974
  Oral tablet
Selinexor (Non-proprietary)
Nexpovio (Menarini Stemline UK Ltd)
  selpercatinib [Specialist drug] NICE TA742
NICE TA760
NICE TA911
  Oral capsule
Retsevmo (Eli Lilly and Company Ltd)
  sorafenib [Specialist drug] Hospital Only NICE TA178
NICE TA474
NICE TA535
  Oral tablet
Sorafenib (Non-proprietary)
Nexavar (Bayer Plc)
  sotorasib [Specialist drug] NICE TA781
  Oral tablet
Lumykras (Amgen Ltd)
  sunitinib [Specialist drug] Hospital Only NICE TA169
NICE TA179
NICE TA178
NICE TA449
  Oral capsule
Sunitinib (Non-proprietary)
Sutent (Pfizer Ltd)
  talazoparib [Specialist drug] NICE TA952
  Oral capsule
Talazoparib (Non-proprietary)
Talzenna (Pfizer Ltd)
  tebentafusp [Specialist drug]
  Solution for infusion
Kimmtrak (Immunocore Ltd)
  temsirolimus [Specialist drug] Hospital Only NICE TA178
  Solution for infusion
Torisel (Pfizer Ltd)
  tepotinib [Specialist drug] NICE TA789
  Oral tablet
Tepmetko (Merck Serono Ltd)
  tivozanib [Specialist drug] Hospital Only NICE TA512
  Oral capsule
Fotivda (Recordati UK Ltd)
  trametinib [Specialist drug] Hospital Only NICE TA396
NICE TA544
  Oral tablet
Mekinist (Novartis Pharmaceuticals UK Ltd)
  tucatinib [Specialist drug] NICE TA786
  Oral tablet
Tukysa (Pfizer Ltd)
  vandetanib [Specialist drug] Hospital Only NICE TA550
  Oral tablet
Caprelsa (Sanofi)
  vemurafenib [Specialist drug] Hospital Only NICE TA269
  Oral tablet
Zelboraf (Roche Products Ltd)
  venetoclax [Specialist drug] Hospital Only NICE TA561
NICE TA663
NICE TA796
NICE TA765
NICE TA787
  Oral tablet
Venclyxto (AbbVie Ltd)
  vismodegib [Specialist drug] Off Formulary NICE TA489
Vismodegib Prescribing

  Oral capsule
Erivedge (Roche Products Ltd)
  zanubrutinib [Specialist drug] NICE TA833
NICE TA931
  Oral capsule
Brukinsa (BeiGene UK Ltd)
Malignant disease / Cytotoxic responsive malignancy
  DACTINOMYCIN Hospital Only
  amsacrine [Specialist drug]
  arsenic trioxide [Specialist drug] Hospital Only NICE TA526
  Solution for infusion
Arsenic trioxide (Non-proprietary)
Trisenox (Teva UK Ltd)
  asparaginase [Specialist drug] Hospital Only
  Powder for solution for infusion
Spectrila (medac UK)
  azacitidine [Specialist drug] Hospital Only NICE TA218
NICE TA399
NICE TA827
  Powder for suspension for injection
Azacitidine (Non-proprietary)
Vidaza (Bristol-Myers Squibb Pharmaceuticals Ltd)
  Oral tablet
Onureg (Bristol-Myers Squibb Pharmaceuticals Ltd)
  bendamustine hydrochloride [Specialist drug] Hospital Only NICE TA216
NICE TA472
BENDAMUSTINE HYDROCHLORIDE

HOSPITAL ONLY

  Powder for solution for infusion
Bendamustine hydrochloride (Non-proprietary)
  bexarotene [Specialist drug] Off Formulary
BEXAROTENE

HOSPITAL ONLY

  Oral capsule
Bexarotene (Non-proprietary)
Targretin (Eisai Ltd)
  bleomycin [Specialist drug] Hospital Only
Bleomycin monitoring algorithm

Bleomycin monitoring algorithm

Bleomycin for lymphangioma

The JPG supported the use of bleomycin as sclerotherapy for treatment of lymphovenous malformations for adults.  Protocol to follow.

  Powder for solution for injection
Bleomycin (Non-proprietary)
  busulfan [Specialist drug] Hospital Only
  Solution for infusion
Busulfan (Non-proprietary)
  Oral tablet
Busulfan (Non-proprietary)
  cabazitaxel [Specialist drug] Hospital Only NICE TA391
  Solution for infusion
Cabazitaxel (Non-proprietary)
  capecitabine [Specialist drug] Hospital Only NICE TA263
NICE TA212
NICE TA191
NICE TA61
NICE TA100
  Oral tablet
Capecitabine (Non-proprietary)
  carboplatin [Specialist drug] Hospital Only NICE TA284
NICE TA285
  Solution for infusion
Carboplatin (Non-proprietary)
  carmustine [Specialist drug] Hospital Only NICE TA121
  Prolonged-release intralesional implant
Gliadel (Clinigen Healthcare Ltd)
  chlorambucil [Specialist drug] Hospital Only NICE TA343
NICE TA344
  Oral tablet
Chlorambucil (Non-proprietary)
  chlormethine [Specialist drug] NICE TA720
  Cutaneous gel
Ledaga (Recordati Rare Diseases UK Ltd)
  cisplatin [Specialist drug] Hospital Only
  Solution for infusion
Cisplatin (Non-proprietary)
  cladribine Hospital Only NICE TA616
  Solution for injection
Litak (Lipomed GmbH)
  Solution for infusion
Leustat (Atnahs Pharma UK Ltd)
  Oral tablet
Mavenclad (Merck Serono Ltd)
  clofarabine [Specialist drug] Hospital Only
  Solution for infusion
Clofarabine (Non-proprietary)
  crisantaspase [Specialist drug] Off Formulary
  Powder for solution for injection
Erwinase (Porton Biopharma Ltd)
  cyclophosphamide Hospital Only
  Powder for solution for injection
Cyclophosphamide (Non-proprietary) Hospital Only
Cyclophosphamide

For Hospital Use Only

  Oral tablet
Cyclophosphamide (Non-proprietary)
Cytoxan (Imported (United States))
  cytarabine [Specialist drug] Hospital Only
  Solution for injection
Cytarabine (Non-proprietary)
  dacarbazine [Specialist drug] Hospital Only
  Powder for solution for injection
Dacarbazine (Non-proprietary) On Formulary
  Powder for solution for infusion
Dacarbazine (Non-proprietary)
  daunorubicin [Specialist drug] Hospital Only
  Powder for solution for infusion
Daunorubicin (Non-proprietary)
  daunorubicin with cytarabine [Specialist drug] Hospital Only NICE TA552
  Powder for solution for infusion
Vyxeos (Jazz Pharmaceuticals UK Ltd)
  decitabine [Specialist drug] Hospital Only
  Powder for solution for infusion
Dacogen (Janssen-Cilag Ltd)
  decitabine with cedazuridine [Specialist drug]
  Oral tablet
Inaqovi (Otsuka Pharmaceuticals (U.K.) Ltd)
  docetaxel [Specialist drug] Hospital Only NICE TA101
NICE TA509
  Solution for infusion
Docetaxel (Non-proprietary)
  doxorubicin hydrochloride [Specialist drug] Hospital Only NICE TA389
NICE TA465
  Solution for injection
Doxorubicin hydrochloride (Non-proprietary)
  Solution for infusion
Doxorubicin hydrochloride (Non-proprietary)
  epirubicin hydrochloride [Specialist drug] Hospital Only
  Solution for injection
Epirubicin hydrochloride (Non-proprietary)
Pharmorubicin (Pfizer Ltd)
  Solution for infusion
Epirubicin hydrochloride (Non-proprietary)
  eribulin [Specialist drug] Hospital Only NICE TA423
NICE TA515
  Solution for injection
Halaven (Eisai Ltd)
  estramustine phosphate [Specialist drug] Off Formulary
  etoposide [Specialist drug] Hospital Only
  Powder for solution for injection
Etopophos (Neon Healthcare Ltd) On Formulary
Vinca alkaloids and etoposide

HOSPITAL ONLY

PLEASE REFER TO FULL CHEMOTHERAPY GUIDELINES

  Solution for infusion
Etoposide (Non-proprietary) On Formulary
Vinca alkaloids and etoposide

HOSPITAL ONLY

PLEASE REFER TO FULL CHEMOTHERAPY GUIDELINES

  Oral capsule
Etoposide (Non-proprietary)
  fludarabine phosphate [Specialist drug] Hospital Only NICE TA119
NICE TA29
  Solution for injection
Fludarabine phosphate (Non-proprietary)
  Powder for solution for injection
Fludarabine phosphate (Non-proprietary)
Fludara (Sanofi)
  Oral tablet
Fludara (Sanofi)
  fluorouracil Hospital Only
  Solution for injection
Fluorouracil (Non-proprietary)
  Solution for infusion
Fluorouracil (Non-proprietary)
  Cutaneous cream
Fluorouracil (Non-proprietary)
Efudix (Viatris UK Healthcare Ltd)
  gemcitabine [Specialist drug] Hospital Only NICE TA25
NICE TA116
NICE TA285
NICE TA389
NICE TA476
  Solution for infusion
Gemcitabine (Non-proprietary)
  Powder for solution for infusion
Gemcitabine (Non-proprietary)
  hydroxycarbamide Hospital Only
HOSPITAL ONLY

 EXCEPT AS PART OF SHARED CARE

Hydroxyurea shared care guidance

HYDROXYCARBAMIDE (HYDROXYUREA) For the Management of Sickle Cell Disease in Adults and Children

  Oral solution
Xromi (Nova Laboratories Ltd)
  Oral tablet
Siklos (Masters Pharmaceuticals Ltd)
  Oral capsule
Hydroxycarbamide (Non-proprietary)
Droxia (Imported (United States))
Hydrea (Neon Healthcare Ltd)
  idarubicin hydrochloride [Specialist drug] Hospital Only
  Oral capsule
Zavedos (Pfizer Ltd)
  ifosfamide [Specialist drug] Hospital Only
  Powder for solution for injection
Ifosfamide (Non-proprietary) On Formulary
Ifosfamide

For Hospital Use Only

  irinotecan hydrochloride [Specialist drug] Hospital Only NICE TA440
  Solution for infusion
Irinotecan hydrochloride (Non-proprietary)
Campto (Pfizer Ltd)
  Dispersion for infusion
Onivyde (Servier Laboratories Ltd)
  lomustine [Specialist drug] Hospital Only
  Oral capsule
Lomustine (Non-proprietary)
  melphalan [Specialist drug] Hospital Only
  Powder and solvent for solution for injection
Melphalan (Non-proprietary) Hospital Only
  Oral tablet
Melphalan (Non-proprietary)
  mercaptopurine Hospital Only
IBD Shared Care Guidelines 2019

IBD Shared Care Guidelines

  Oral suspension
Xaluprine (Nova Laboratories Ltd)
  Oral tablet
Mercaptopurine (Non-proprietary)
Hanixol (Fontus Health Ltd)
  methotrexate Hospital Only
IBD Shared Care Guidelines 2019

IBD Shared Care Guidelines

Methotrexate oral: Trust Policy

see attached

  Oral solution
Methotrexate (Non-proprietary)
Jylamvo (Esteve Pharmaceuticals Ltd)
  Solution for injection
Methotrexate (Non-proprietary)
Methofill (Accord-UK Ltd)
Metoject PEN (medac UK)
Nordimet (Nordic Pharma Ltd)
Zlatal (Nordic Pharma Ltd)
  Solution for infusion
Methotrexate (Non-proprietary)
  Oral tablet
Methotrexate (Non-proprietary)
Maxtrex (Pfizer Ltd)
  mitomycin [Specialist drug] Hospital Only
Mitomycin Proforma

  Powder for solution for injection
Mitomycin (Non-proprietary)
Mitocin (Vygoris Ltd)
  Powder and solvent for intravesical solution
Mitomycin (Non-proprietary)
  mitotane [Specialist drug] Hospital Only
  Oral tablet
Lysodren (Esteve RD UK & Ireland Ltd)
  mitoxantrone [Specialist drug] Hospital Only
  Solution for infusion
Onkotrone (Baxter Healthcare Ltd)
  nelarabine [Specialist drug] Hospital Only
  Solution for infusion
Atriance (Sandoz Ltd)
  oxaliplatin [Specialist drug] Hospital Only NICE TA100
NICE TA93
  Solution for infusion
Oxaliplatin (Non-proprietary)
  paclitaxel [Specialist drug] Hospital Only NICE TA55
NICE TA284
NICE TA389
NICE TA476
  Solution for infusion
Paclitaxel (Non-proprietary)
  Powder for suspension for infusion
Abraxane (Bristol-Myers Squibb Pharmaceuticals Ltd)
  panobinostat [Specialist drug] Hospital Only NICE TA380
  Oral capsule
Farydak (pharmaand GmbH)
  pegaspargase [Specialist drug] Hospital Only NICE TA408
  Powder for solution for injection
Oncaspar (Servier Laboratories Ltd)
  pemetrexed [Specialist drug] Hospital Only NICE TA124
NICE TA181
NICE TA402
NICE TA190
NICE TA135
  Solution for infusion
Pemetrexed (Non-proprietary)
  Powder for solution for infusion
Pemetrexed (Non-proprietary)
Alimta (Eli Lilly and Company Ltd)
  pentostatin [Specialist drug] Hospital Only
  Powder for solution for injection
Nipent (Pfizer Ltd)
  pixantrone [Specialist drug] Hospital Only NICE TA306
  Powder for solution for infusion
Pixuvri (Servier Laboratories Ltd)
  procarbazine [Specialist drug] Hospital Only
  Oral capsule
Procarbazine (Non-proprietary)
  raltitrexed [Specialist drug] Hospital Only
  Powder for solution for infusion
Tomudex (Pfizer Ltd)
  ropeginterferon alfa-2b [Specialist drug]
  Solution for injection
Besremi (AOP Orphan Ltd)
  streptozocin [Specialist drug] Hospital Only
  Powder for solution for infusion
Zanosar (Esteve Pharmaceuticals Ltd)
  tegafur with gimeracil and oteracil [Specialist drug] Hospital Only
  temozolomide [Specialist drug] Hospital Only NICE TA23
NICE TA121
  Oral capsule
Temozolomide (Non-proprietary)
Temodal (Merck Sharp & Dohme (UK) Ltd)
  thiotepa [Specialist drug] Hospital Only
  Powder for solution for infusion
Thiotepa (Non-proprietary)
Tepadina (Adienne Pharma & Biotech)
  tioguanine [Specialist drug] Hospital Only
  Oral tablet
Tioguanine (Non-proprietary)
  topotecan [Specialist drug] Hospital Only NICE TA183
NICE TA184
NICE TA389
June 2024 - Topotecan intravitreal injection – elevated doses in the treatment of paediatric retinoblastoma patients in BH

Topotecan intravitreal injection approved at NEL FPG for elevated doses in the treatment of paediatric retinoblastoma patients in Barts Health

 

Formulary Status: Hospital Only

  Solution for infusion
Topotecan (Non-proprietary)
  Oral capsule
Hycamtin (Sandoz Ltd)
  trabectedin [Specialist drug] Hospital Only NICE TA185
NICE TA389
  Powder for solution for infusion
Trabectedin (Non-proprietary)
Yondelis (Immedica Pharma AB)
  treosulfan [Specialist drug] Hospital Only NICE TA640
  Powder for solution for injection
Treosulfan (Non-proprietary) On Formulary
Trecondi (medac UK)
  tretinoin [Specialist drug] Hospital Only
  Oral capsule
Tretinoin (Non-proprietary)
  trifluridine with tipiracil [Specialist drug] Hospital Only NICE TA405
NICE TA852
  Oral tablet
Lonsurf (Servier Laboratories Ltd)
  vinblastine sulfate [Specialist drug] Hospital Only
  Solution for injection
Vinblastine sulfate (Non-proprietary)
  vincristine sulfate [Specialist drug] Hospital Only
  Solution for injection
Vincristine sulfate (Non-proprietary)
  vindesine sulfate [Specialist drug] Hospital Only
  Powder for solution for injection
Eldisine (Genus Pharmaceuticals Ltd)
  vinorelbine [Specialist drug] Hospital Only
  Solution for infusion
Vinorelbine (Non-proprietary)
Navelbine (Pierre Fabre Ltd)
  Oral capsule
Vinorelbine (Non-proprietary)
Navelbine (Pierre Fabre Ltd)
Malignant disease / Cytotoxic drug-induced side effects
  dexrazoxane Off Formulary
  Powder for solution for infusion
Cardioxane (CNX Therapeutics Ltd)
  Powder and solvent for solution for infusion
Savene (Clinigen Healthcare Ltd)
  folinic acid Hospital Only NICE TA212
  Solution for injection
Folinic acid (Non-proprietary) Hospital Only
Antidotes List

see attached

Sodiofolin (medac UK)
  Oral tablet
Folinic acid (Non-proprietary)
Refolinon (Pfizer Ltd)
  glucarpidase
  Powder for solution for injection
Voraxaze (Protherics Medicines Development Ltd)
  levofolinic acid Hospital Only
  Solution for injection
Levofolinic acid (Non-proprietary)
Isovorin (Pfizer Ltd)
  mesna Hospital Only
  Solution for injection
Mesna (Non-proprietary) Hospital Only
Mesna

For Hospital Use Only

  Oral tablet
Mesna (Non-proprietary)
Malignant disease / Hyperuricaemia associated with cytotoxic drugs
  allopurinol On Formulary
  Oral tablet
Allopurinol (Non-proprietary)
Zyloric (Aspen Pharma Trading Ltd)
  febuxostat On Formulary NICE TA164
  Oral tablet
Febuxostat (Non-proprietary)
Adenuric (A. Menarini Farmaceutica Internazionale SRL)
Elstabya (Amarox Ltd)
  rasburicase On Formulary
  Powder and solvent for solution for infusion
Fasturtec (Sanofi) On Formulary
Fasturtec®

For Hospital Use Only

Malignant disease / Hormone responsive malignancy
  abiraterone acetate Hospital Only NICE TA259
NICE TA387
NICE TA721
  Oral tablet
Abiraterone acetate (Non-proprietary)
Zytiga (Janssen-Cilag Ltd)
  apalutamide NICE TA740
NICE TA741
  Oral tablet
Apalutamide (Non-proprietary)
Erleada (Janssen-Cilag Ltd)
  bicalutamide On Formulary
  Oral tablet
Bicalutamide (Non-proprietary)
Casodex (AstraZeneca UK Ltd)
  buserelin Hospital Only
  Solution for injection
Buserelin (Non-proprietary)
Suprefact (Neon Healthcare Ltd)
  Spray
Suprecur (Neon Healthcare Ltd)
  cyproterone acetate On Formulary
  Oral tablet
Cyproterone acetate (Non-proprietary)
Androcur (Bayer Plc)
Cyprostat (Bayer Plc)
  darolutamide NICE TA660
NICE TA903
  Oral tablet
Nubeqa (Bayer Plc)
  degarelix On Formulary NICE TA404
Degarelix shared care guideline

Degarelix

  Powder and solvent for solution for injection
Firmagon (Ferring Pharmaceuticals Ltd) On Formulary
Degarelix shared care guideline

  diethylstilbestrol On Formulary
  Oral tablet
Diethylstilbestrol (Non-proprietary)
  enzalutamide Hospital Only NICE TA316
NICE TA377
NICE TA580
NICE TA712
Notes

Patient Information when used in Malignancy

  Oral tablet
Xtandi (Astellas Pharma Ltd)
  ethinylestradiol Off Formulary
  flutamide On Formulary
  Oral tablet
Flutamide (Non-proprietary)
  goserelin On Formulary
GOSERELIN

FOR HOSPITAL USE ONLY for All indications except for treatment of prostate cancer 

Used for endometriosis and fibroids

Proformas

      

  Prolonged-release subcutaneous implant
Zoladex (AstraZeneca UK Ltd)
Zoladex LA (AstraZeneca UK Ltd)
  lanreotide Hospital Only
Lanreotide

 

  • Lanreotide Autogel (Somatuline Autogel) is a licensed long-acting somatostatin analogue used in treatment of Acromegaly to relieve symptoms in patients with carcinoid tumors.
  • There is also lanreotide LA which is shorter acting – and not kept in pharmacy 

  Solution for injection
Lanreotide (Non-proprietary)
Somatuline Autogel (Ipsen Ltd) Hospital Only
Lanreotide

 

  • Lanreotide Autogel (Somatuline Autogel) is a licensed long-acting somatostatin analogue used in treatment of Acromegaly to relieve symptoms in patients with carcinoid tumors.
  • There is also lanreotide LA which is shorter acting – and not kept in pharmacy 

Note:

For HOSPITAL use only

  leuprorelin acetate Hospital Only
  Powder and solvent for suspension for injection
Prostap 3 DCS (Takeda UK Ltd) On Formulary
Prostap® 3 DCS

Endometriosis and fibroids (un-licensed)

Prostap SR DCS (Takeda UK Ltd) On Formulary
  Prolonged-release subcutaneous implant
Staladex (Aspire Pharma Ltd)
  medroxyprogesterone acetate On Formulary
  Suspension for injection
Depo-Provera (Pfizer Ltd) Hospital Only
Sayana Press (Pfizer Ltd)
Medroxyprogesterone acetate subcutaneous injection


Sayana Press - the SC form of medroxyprogesterone acetate -  is on formulary for patients who are willing and able to self administer the injection.  It is an alternative to the intramuscular form.

  Oral tablet
Provera (Pfizer Ltd)
  megestrol acetate On Formulary
  Oral suspension
Megestrol acetate (Non-proprietary)
  Oral tablet
Megestrol acetate (Non-proprietary)
Megace (Bausch & Lomb UK Ltd)
  norethisterone Hospital Only
  Solution for injection
Noristerat (Bayer Plc)
  Oral tablet
Norethisterone (Non-proprietary)
Noriday (Pfizer Ltd)
Primolut N (Bayer Plc)
Utovlan (Pfizer Ltd)
  octreotide Hospital Only
Octreotide LAR

 

  • Octreotide is a licensed long acting somatostation analogue used in the treatment of acromegaly & neuroendocrine neoplasms. Injections are administered once a month once patients have been converted from regular Octreotide.

OCTREOTIDE

FOR HOSPITAL USE ONLY

Used for neuroendocrine tumours (carcinoid syndrome)

Octreotide in pancreatic surgery

  Solution for injection
Octreotide (Non-proprietary) Hospital Only
Octreotide LAR

 

  • Octreotide is a licensed long acting somatostation analogue used in the treatment of acromegaly & neuroendocrine neoplasms. Injections are administered once a month once patients have been converted from regular Octreotide.

Octreotide in pancreatic surgery

Octreotide

FOR HOSPITAL USE ONLY

Sandostatin (Novartis Pharmaceuticals UK Ltd) Hospital Only
OCTREOTIDE

FOR HOSPITAL USE ONLY

Used for neuroendocrine tumours (carcinoid syndrome)

Octreotide LAR

 

  • Octreotide is a licensed long acting somatostation analogue used in the treatment of acromegaly & neuroendocrine neoplasms. Injections are administered once a month once patients have been converted from regular Octreotide.

Octreotide in pancreatic surgery

  Powder and solvent for suspension for injection
Olatuton (Teva UK Ltd)
Sandostatin LAR (Novartis Pharmaceuticals UK Ltd) Hospital Only
Octreotide LAR

 

  • Octreotide is a licensed long acting somatostation analogue used in the treatment of acromegaly & neuroendocrine neoplasms. Injections are administered once a month once patients have been converted from regular Octreotide.

Octreotide in pancreatic surgery

Sandostatin Lar®

FOR HOSPITAL USE ONLY

  pasireotide
  Solution for injection
Signifor (Recordati Rare Diseases UK Ltd)
  Powder and solvent for suspension for injection
Signifor (Recordati Rare Diseases UK Ltd)
  relugolix NICE TA995
  Oral tablet
Orgovyx (Accord-UK Ltd)
  triptorelin Hospital Only
  Powder and solvent for suspension for injection
Decapeptyl SR (Ipsen Ltd)
Gonapeptyl Depot (Ferring Pharmaceuticals Ltd)
Salvacyl (Ipsen Ltd)
Malignant disease / Hormone responsive breast cancer
  anastrozole On Formulary
  Oral tablet
Anastrozole (Non-proprietary)
Arimidex (AstraZeneca UK Ltd)
  exemestane On Formulary
  Oral tablet
Exemestane (Non-proprietary)
Aromasin (Pfizer Ltd)
  fulvestrant On Formulary NICE TA503
  Solution for injection
Fulvestrant (Non-proprietary)
Faslodex (AstraZeneca UK Ltd) On Formulary
  letrozole On Formulary
  Oral tablet
Letrozole (Non-proprietary)
Femara (Novartis Pharmaceuticals UK Ltd)
  tamoxifen On Formulary
  Oral solution
Tamoxifen (Non-proprietary) On Formulary
  Oral tablet
Tamoxifen (Non-proprietary)
  toremifene Off Formulary
  Oral tablet
Fareston (Orion Pharma (UK) Ltd)
Malignant disease / Photodynamic therapy responsive malignancy
  temoporfin [Specialist drug] Hospital Only
  Solution for injection
Foscan (Biolitec Pharma Ltd)
Malignant disease / Secondary bone metastases and hypercalcaemia
  calcitonin (salmon) On Formulary
CALCITONIN (SALMON)/SALCATONIN

IV FORMULATION IS FOR  HOSPITAL USE ONLY

  Solution for injection
Calcitonin (salmon) (Non-proprietary) Hospital Only
Calcitonin (salmon)

HOSPITAL ONLY

  denosumab Hospital Only NICE TA204
NICE TA265
HOSPITAL ONLY USE

Skeletal related events in cancer

Osteoporosis in postmenopausal women and in men at increased risk of fractures ( March 2022)

 

Approved  in hospital for secondary prevention of osteoporosis in men and women 60 years or over, who meet the following inclusion criteria:

1.    Patients with severe renal impairment.

2.    Patients who are intolerant and with contraindications to bisphosphonate therapy.

3.    Patients with severe vertebral osteoporosis.

  Solution for injection
Denosumab (Non-proprietary)
Prolia (Amgen Ltd) On Formulary
Xgeva (Amgen Ltd) On Formulary
  ibandronic acid Off Formulary NICE TA464
IBANDRONIC ACID

IV FORMULATION IS FOR HOSPITAL USE ONLY

  Solution for injection
Ibandronic acid (Non-proprietary)
Bonviva (Atnahs Pharma UK Ltd)
  Solution for infusion
Ibandronic acid (Non-proprietary)
Bondronat (Atnahs Pharma UK Ltd)
  Oral tablet
Ibandronic acid (Non-proprietary)
Bondronat (Atnahs Pharma UK Ltd)
Bonviva (Atnahs Pharma UK Ltd)
Iasibon (Aspire Pharma Ltd)
  pamidronate disodium On Formulary
PAMIDRONATE DISODIUM

FOR HOSPITAL USE ONLY

Hypercalcaemia-will decrease calcium after 24 hours (5-6 days for the full effect). Effects last 14-21 days

  Solution for infusion
Pamidronate disodium (Non-proprietary) On Formulary
PAMIDRONATE DISODIUM

FOR HOSPITAL USE ONLY

Hypercalcaemia-will decrease calcium after 24 hours (5-6 days for the full effect). Effects last 14-21 days

  sodium clodronate Hospital Only
  Oral tablet
Clasteon (Kent Pharma (UK) Ltd)
Loron (Esteve Pharmaceuticals Ltd)
  Oral capsule
Sodium clodronate (Non-proprietary)
Clasteon (Kent Pharma (UK) Ltd)
  zoledronic acid Hospital Only NICE TA464
  Infusion
Zoledronic acid (Non-proprietary)
Aclasta (Sandoz Ltd)
Zometa (Phoenix Labs Ltd) On Formulary
  Solution for infusion
Zoledronic acid (Non-proprietary)
Zometa (Phoenix Labs Ltd) On Formulary