Malignant disease
/ Antibody responsive malignancy
|
|
amivantamab [Specialist drug]
|
|
NICE TA850
|
|
Solution for infusion |
|
Rybrevant (Janssen-Cilag Ltd)
|
|
|
atezolizumab [Specialist drug]
|
Hospital Only
|
NICE TA525
NICE TA739
NICE TA520
NICE TA584
NICE TA705
NICE TA823
NICE TA638
NICE TA639
NICE TA666
|
|
Solution for infusion |
|
Tecentriq (Roche Products Ltd)
|
|
|
avelumab [Specialist drug]
|
Hospital Only
|
NICE TA517
NICE TA691
NICE TA645
NICE TA788
|
|
Solution for infusion |
|
Bavencio (Merck Serono Ltd)
|
|
|
belantamab mafodotin [Specialist drug]
|
|
|
|
Powder for solution for infusion |
|
Blenrep (GlaxoSmithKline UK Ltd)
|
|
|
bevacizumab [Specialist drug]
|
Hospital Only
|
NICE TA118
NICE TA212
NICE TA242
NICE TA178
NICE TA214
NICE TA263
NICE TA284
NICE TA285
NICE TA666
NICE TA946
|
|
Bevacizumab
HOSPITAL ONLY
UNLICENSED
-
For the treatment of rubeotic glaucoma where there is an intraocular pressure >28mm Hg secondary to iris rubeosis, where pan-retinal laser treatment has been ineffective. All prescribing and administration will be carried out by a consultant ophthalmologist specialised in the management of this condition.
-
The drug will be stopped if there is regression of iris rubeosis, and an intraocular pressure of <21mm Hg (on topical therapy), or an assessment of clinically inactive iris rubeosis.
-
As the drug is both unlicensed in this condition and supplied as a formulation for intravitreal injection from a specials unit, the patient must be educated on the use of the medication and consent documented in the patient record.
-
The cost of drug, supplied as 1.25mg in 0.05ml, will be funded by the Ophthalmology Department as the cost is sufficiently covered within the tariff charged for an injection in outpatients.
-
As the drug is ordered in specially, the dose must be requested in good time. Please liaise with Kamini Patel at Whipps Cross to organise this to avoid any problems with doses not being ready.
-
The patient numbers are estimated to be around 3-5 per annum.
|
|
|
Solution for infusion |
|
Alymsys (Zentiva Pharma UK Ltd)
|
|
|
Avastin (Roche Products Ltd)
|
On Formulary
|
|
Bevacizumab
HOSPITAL ONLY
UNLICENSED
-
For the treatment of rubeotic glaucoma where there is an intraocular pressure >28mm Hg secondary to iris rubeosis, where pan-retinal laser treatment has been ineffective. All prescribing and administration will be carried out by a consultant ophthalmologist specialised in the management of this condition.
-
The drug will be stopped if there is regression of iris rubeosis, and an intraocular pressure of <21mm Hg (on topical therapy), or an assessment of clinically inactive iris rubeosis.
-
As the drug is both unlicensed in this condition and supplied as a formulation for intravitreal injection from a specials unit, the patient must be educated on the use of the medication and consent documented in the patient record.
-
The cost of drug, supplied as 1.25mg in 0.05ml, will be funded by the Ophthalmology Department as the cost is sufficiently covered within the tariff charged for an injection in outpatients.
-
As the drug is ordered in specially, the dose must be requested in good time. Please liaise with Kamini Patel at Whipps Cross to organise this to avoid any problems with doses not being ready.
-
The patient numbers are estimated to be around 3-5 per annum.
|
|
|
Avastin®
To be sourced from Royal Free for patients with rubeotic glaucoma (elective treatment)
|
|
|
Aybintio (Organon Pharma (UK) Ltd)
|
|
|
Oyavas (Thornton & Ross Ltd)
|
|
|
Vegzelma (Celltrion Healthcare UK Ltd)
|
|
|
Versavo (Dr Reddy's Laboratories (UK) Ltd)
|
|
|
Zirabev (Pfizer Ltd)
|
|
|
blinatumomab [Specialist drug]
|
Hospital Only
|
NICE TA450
NICE TA589
|
|
Powder for solution for infusion |
|
Blincyto (Amgen Ltd)
|
|
|
brentuximab vedotin [Specialist drug]
|
Hospital Only
|
NICE TA478
NICE TA641
NICE TA524
NICE TA577
|
|
Powder for solution for infusion |
|
Adcetris (Takeda UK Ltd)
|
|
|
cemiplimab [Specialist drug]
|
|
NICE TA802
|
|
Solution for infusion |
|
Libtayo (Regeneron UK Ltd)
|
|
|
cetuximab [Specialist drug]
|
Hospital Only
|
NICE TA145
NICE TA473
NICE TA242
NICE TA439
NICE TA668
|
|
Solution for infusion |
|
Erbitux (Merck Serono Ltd)
|
On Formulary
|
|
Cetuximab prescribing
|
|
|
Erbitux®
For large bowel cancers
|
|
|
daratumumab
|
Hospital Only
|
NICE TA763
NICE TA783
NICE TA897
NICE TA917
NICE TA959
|
|
Solution for injection |
|
Darzalex (Janssen-Cilag Ltd)
|
|
|
Solution for infusion |
|
Darzalex (Janssen-Cilag Ltd)
|
|
|
dinutuximab beta [Specialist drug]
|
Off Formulary
|
NICE TA538
|
|
Solution for infusion |
|
Qarziba (Recordati UK Ltd)
|
|
|
dostarlimab [Specialist drug]
|
|
NICE TA779
NICE TA963
|
|
Solution for infusion |
|
Jemperli (GlaxoSmithKline UK Ltd)
|
|
|
durvalumab [Specialist drug]
|
Hospital Only
|
NICE TA798
NICE TA944
|
|
Solution for infusion |
|
Imfinzi (AstraZeneca UK Ltd)
|
|
|
elotuzumab [Specialist drug]
|
Off Formulary
|
|
|
Powder for solution for infusion |
|
Empliciti (Bristol-Myers Squibb Pharmaceuticals Ltd)
|
|
|
elranatamab [Specialist drug]
|
|
|
|
Solution for injection |
|
Elrexfio (Pfizer Ltd)
|
|
|
enfortumab vedotin [Specialist drug]
|
|
|
|
Powder for solution for infusion |
|
Padcev (Astellas Pharma Ltd)
|
|
|
epcoritamab [Specialist drug]
|
|
NICE TA954
|
|
Solution for injection |
|
Tepkinly (AbbVie Ltd)
|
|
|
gemtuzumab ozogamicin [Specialist drug]
|
Hospital Only
|
NICE TA545
|
|
Powder for solution for infusion |
|
Mylotarg (Pfizer Ltd)
|
|
|
glofitamab [Specialist drug]
|
|
NICE TA927
|
|
Solution for infusion |
|
Columvi (Roche Products Ltd)
|
|
|
inotuzumab ozogamicin [Specialist drug]
|
Hospital Only
|
NICE TA541
|
|
Powder for solution for infusion |
|
Besponsa (Pfizer Ltd)
|
|
|
ipilimumab [Specialist drug]
|
Hospital Only
|
NICE TA268
NICE TA319
NICE TA400
NICE TA716
NICE TA724
NICE TA780
NICE TA818
|
|
Solution for infusion |
|
Yervoy (Bristol-Myers Squibb Pharmaceuticals Ltd)
|
|
|
isatuximab [Specialist drug]
|
Hospital Only
|
NICE TA658
|
|
Approved by Cancer DTC
December 2020
|
|
|
Solution for infusion |
|
Sarclisa (Sanofi)
|
|
|
loncastuximab tesirine [Specialist drug]
|
|
NICE TA947
|
|
Powder for solution for infusion |
|
Zynlonta (Swedish Orphan Biovitrum Ltd)
|
|
|
mogamulizumab [Specialist drug]
|
|
NICE TA754
NICE TA754
|
|
Solution for infusion |
|
Poteligeo (Kyowa Kirin Ltd)
|
|
|
mosunetuzumab [Specialist drug]
|
|
NICE TA892
|
|
Solution for infusion |
|
Lunsumio (Roche Products Ltd)
|
|
|
nivolumab [Specialist drug]
|
Hospital Only
|
NICE TA384
NICE TA400
NICE TA684
NICE TA417
NICE TA780
NICE TA964
NICE TA462
NICE TA655
NICE TA713
NICE TA724
NICE TA876
NICE TA530
NICE TA817
NICE TA707
NICE TA746
NICE TA857
NICE TA865
NICE TA716
NICE TA736
NICE TA818
|
|
Solution for infusion |
|
Opdivo (Bristol-Myers Squibb Pharmaceuticals Ltd)
|
|
|
nivolumab with relatlimab [Specialist drug]
|
|
NICE TA950
|
|
Solution for infusion |
|
Opdualag (Bristol-Myers Squibb Pharmaceuticals Ltd)
|
|
|
obinutuzumab [Specialist drug]
|
Hospital Only
|
NICE TA343
NICE TA513
NICE TA629
|
|
Solution for infusion |
|
Gazyvaro (Roche Products Ltd)
|
|
|
panitumumab [Specialist drug]
|
Hospital Only
|
NICE TA242
NICE TA439
|
|
Solution for infusion |
|
Vectibix (Amgen Ltd)
|
|
|
pembrolizumab [Specialist drug]
|
Hospital Only
|
NICE TA357
NICE TA366
NICE TA766
NICE TA837
NICE TA428
NICE TA531
NICE TA683
NICE TA770
NICE TA692
NICE TA772
NICE TA540
NICE TA967
NICE TA650
NICE TA830
NICE TA858
NICE TA661
NICE TA709
NICE TA914
NICE TA983
NICE TA737
NICE TA997
NICE TA801
NICE TA851
NICE TA939
NICE TA904
|
|
Solution for infusion |
|
Keytruda (Merck Sharp & Dohme (UK) Ltd)
|
|
|
pertuzumab [Specialist drug]
|
Hospital Only
|
NICE TA424
NICE TA509
NICE TA569
|
|
Solution for infusion |
|
Perjeta (Roche Products Ltd)
|
|
|
pertuzumab with trastuzumab [Specialist drug]
|
|
|
|
Solution for injection |
|
Phesgo (Roche Products Ltd)
|
|
|
polatuzumab vedotin [Specialist drug]
|
Hospital Only
|
NICE TA649
NICE TA874
|
|
Approved by Cancer DTC
November 2020
|
|
|
Powder for solution for infusion |
|
Polivy (Roche Products Ltd)
|
|
|
ramucirumab [Specialist drug]
|
Hospital Only
|
NICE TA378
NICE TA403
|
|
Solution for infusion |
|
Cyramza (Eli Lilly and Company Ltd)
|
|
|
rituximab
|
Hospital Only
|
NICE TA308
NICE TA195
NICE TA243
NICE TA137
NICE TA193
NICE TA226
NICE TA174
NICE TA359
NICE TA561
|
|
Rituximab-Connective Tissue Disease and Hypersensitivity Pneumonitis - Interstitial Lung Disease (CTD-ILD and HP-ILD) (November-2022)
NEL FPG Approved for use in Connective Tissue Disease- Interstitial Lung Disease (CTD-ILD) and Hypersensitivity Pneumonitis- Interstitial Lung Disease (HP-ILD)
Treatment of Interstitial Lung Disease (ILD) in patients with severe active disease that has failed to respond to, or patient is intolerant to at least 2 immunosuppressants (tacrolimus, methotrexate, mycophenolate or cyclophosphamide), each having been taken for at least 3 months.
Rituximab IV 1g on day 1 and day 15, then repeated 6 monthly if the patient responds.
Hospital Only
|
|
|
RENAL SERVICE
On Formulary for Idiopathic Membraneous Glomerulonephritis,
biopsy-proven, steroid-sensitive minimal change nephropathy or primary focal segmental glomerulosclerosis (non-commissioned).
Renal Transplant Patients
For vasculitis in renal transplant As immunuppression for ABO incompatible transplants
|
|
|
Rituximab use in clinical haematology indications
Truxima brand is used in clinical haematology indications.
|
|
|
Rituximab for the treatment of IgM paraproteinaemic demyelinating peripheral neuropathy in adult
Rituximab for the treatment of IgM paraproteinaemic demyelinating peripheral neuropathy in adults approved for use in May 2022 DTC as per Clinical Commissioning policy SSC2319
|
|
|
Solution for injection |
|
MabThera (Roche Products Ltd)
|
|
|
Solution for infusion |
|
MabThera (Roche Products Ltd)
|
Hospital Only
|
|
Rixathon (Sandoz Ltd)
|
|
|
Ruxience (Pfizer Ltd)
|
|
|
Truxima (Celltrion Healthcare UK Ltd)
|
|
|
sacituzumab govitecan [Specialist drug]
|
|
NICE TA819
|
|
Powder for solution for infusion |
|
Trodelvy (Gilead Sciences Ltd)
|
|
|
siltuximab
|
Off Formulary
|
|
|
Powder for solution for infusion |
|
Sylvant (Recordati UK Ltd)
|
|
|
tafasitamab [Specialist drug]
|
|
NICE TA883
|
|
Powder for solution for infusion |
|
Minjuvi (Incyte Biosciences UK Ltd)
|
|
|
talquetamab [Specialist drug]
|
|
|
|
Solution for injection |
|
Talvey (Janssen-Cilag Ltd)
|
|
|
teclistamab [Specialist drug]
|
|
|
|
Solution for injection |
|
Tecvayli (Janssen-Cilag Ltd)
|
|
|
trastuzumab [Specialist drug]
|
Hospital Only
|
NICE TA34
NICE TA257
NICE TA509
NICE TA208
|
|
Trastuzumab subcutaneous
trastuzumab
|
|
|
Solution for injection |
|
Herceptin (Roche Products Ltd)
|
On Formulary
|
|
Trastuzumab subcutaneous
see attached
|
|
|
Powder for solution for infusion |
|
Herceptin (Roche Products Ltd)
|
|
|
Herzuma (Celltrion Healthcare UK Ltd)
|
|
|
Ontruzant (Organon Pharma (UK) Ltd)
|
|
|
Trazimera (Pfizer Ltd)
|
|
|
Zercepac (Accord-UK Ltd)
|
|
|
trastuzumab deruxtecan [Specialist drug]
|
|
NICE TA704
NICE TA862
NICE TA992
|
|
Powder for solution for infusion |
|
Enhertu (Daiichi Sankyo UK Ltd)
|
|
|
trastuzumab emtansine [Specialist drug]
|
Hospital Only
|
NICE TA458
NICE TA632
|
|
Powder for solution for infusion |
|
Kadcyla (Roche Products Ltd)
|
|
|
tremelimumab [Specialist drug]
|
|
|
|
Solution for infusion |
|
Imjudo (AstraZeneca UK Ltd)
|
|
Malignant disease
/ Carcinoid syndrome
|
|
telotristat ethyl
|
Off Formulary
|
|
|
Oral tablet |
|
Xermelo (SERB)
|
|
Malignant disease
/ Immunotherapy responsive malignancy
|
|
Bacillus Calmette-Guérin [Specialist drug]
|
Hospital Only
|
|
|
Powder for reconstitution for instillation |
|
OncoTICE (Merck Sharp & Dohme (UK) Ltd)
|
On Formulary
|
|
Powder and solvent for intravesical suspension |
|
BCG-medac (medac UK)
|
|
|
aldesleukin [Specialist drug]
|
Hospital Only
|
|
|
ALDESLEUKIN
HOSPITAL ONLY
|
|
|
Powder for solution for injection |
|
Proleukin (Clinigen Healthcare Ltd)
|
Hospital Only
|
|
interferon gamma-1b
|
Off Formulary
|
|
|
Solution for injection |
|
Immukin (Clinigen Healthcare Ltd)
|
|
|
lenalidomide [Specialist drug]
|
Hospital Only
|
NICE TA322
NICE TA171
NICE TA586
NICE TA587
NICE TA627
NICE TA680
|
|
Lenalidomide/Pomalidomide/Thalidomide Prescribing
see attached
|
|
|
Oral capsule |
|
Lenalidomide (Non-proprietary)
|
|
|
Revlimid (Bristol-Myers Squibb Pharmaceuticals Ltd)
|
|
|
mifamurtide [Specialist drug]
|
Off Formulary
|
NICE TA235
|
|
pomalidomide [Specialist drug]
|
Hospital Only
|
NICE TA427
|
|
Lenalidomide/Pomalidomide/Thalidomide Prescribing
see attached
|
|
|
Oral capsule |
|
Imnovid (Bristol-Myers Squibb Pharmaceuticals Ltd)
|
|
|
talimogene laherparepvec [Specialist drug]
|
Hospital Only
|
NICE TA410
|
|
Solution for injection |
|
Imlygic (Amgen Ltd)
|
|
|
thalidomide [Specialist drug]
|
Hospital Only
|
NICE TA228
|
|
Lenalidomide/Pomalidomide/Thalidomide Prescribing
see attached
|
|
|
Oral tablet |
|
Talidex (Special Order)
|
|
|
Oral capsule |
|
Thalidomide (Non-proprietary)
|
|
Malignant disease
/ Targeted therapy responsive malignancy
|
|
abemaciclib [Specialist drug]
|
Hospital Only
|
NICE TA563
NICE TA725
NICE TA810
|
|
Oral tablet |
|
Verzenios (Eli Lilly and Company Ltd)
|
|
|
acalabrutinib [Specialist drug]
|
|
NICE TA689
NICE TA689
|
|
Oral tablet |
|
Calquence (AstraZeneca UK Ltd)
|
|
|
afatinib [Specialist drug]
|
Hospital Only
|
NICE TA310
|
|
Oral tablet |
|
Giotrif (Boehringer Ingelheim Ltd)
|
|
|
aflibercept [Specialist drug]
|
Hospital Only
|
NICE TA294
NICE TA305
NICE TA346
NICE TA409
NICE TA486
NICE TA307
|
|
Solution for injection |
|
Eylea (Bayer Plc)
|
Hospital Only
|
|
Solution for infusion |
|
Zaltrap (Sanofi)
|
Hospital Only
|
|
alectinib [Specialist drug]
|
Hospital Only
|
NICE TA536
|
|
Oral capsule |
|
Alecensa (Roche Products Ltd)
|
|
|
alpelisib [Specialist drug]
|
|
NICE TA816
|
|
Oral tablet |
|
Piqray (Novartis Pharmaceuticals UK Ltd)
|
|
|
asciminib [Specialist drug]
|
|
NICE TA813
|
|
Oral tablet |
|
Scemblix (Novartis Pharmaceuticals UK Ltd)
|
|
|
avapritinib [Specialist drug]
|
|
|
|
Oral tablet |
|
Ayvakyt (Blueprint Medicines (UK) Ltd)
|
|
|
axitinib [Specialist drug]
|
Hospital Only
|
NICE TA333
NICE TA645
NICE TA650
|
|
Oral tablet |
|
Inlyta (Pfizer Ltd)
|
|
|
belzutifan [Specialist drug]
|
|
|
|
Oral tablet |
|
Welireg (Merck Sharp & Dohme (UK) Ltd)
|
|
|
binimetinib [Specialist drug]
|
Hospital Only
|
NICE TA562
|
|
Oral tablet |
|
Mektovi (Pierre Fabre Ltd)
|
|
|
bortezomib [Specialist drug]
|
Hospital Only
|
NICE TA370
NICE TA311
NICE TA228
NICE TA129
|
|
Solution for injection |
|
Bortezomib (Non-proprietary)
|
|
|
Powder for solution for injection |
|
Bortezomib (Non-proprietary)
|
|
|
Velcade (Janssen-Cilag Ltd)
|
On Formulary
|
|
bosutinib [Specialist drug]
|
Hospital Only
|
NICE TA401
|
|
Oral tablet |
|
Bosulif (Pfizer Ltd)
|
|
|
brigatinib [Specialist drug]
|
Hospital Only
|
NICE TA571
NICE TA670
|
|
Form unstated |
|
Alunbrig (Takeda UK Ltd)
|
|
|
Oral tablet |
|
Alunbrig (Takeda UK Ltd)
|
|
|
cabozantinib [Specialist drug]
|
Hospital Only
|
NICE TA463
NICE TA542
NICE TA964
NICE TA516
NICE TA928
NICE TA849
|
|
Form unstated |
|
Cometriq (Ipsen Ltd)
|
|
|
Oral tablet |
|
Cabometyx (Ipsen Ltd)
|
|
|
Oral capsule |
|
Cometriq (Ipsen Ltd)
|
|
|
carfilzomib [Specialist drug]
|
Hospital Only
|
NICE TA657
NICE TA695
|
|
Powder for solution for infusion |
|
Kyprolis (Amgen Ltd)
|
|
|
ceritinib [Specialist drug]
|
Hospital Only
|
NICE TA395
NICE TA500
|
|
Oral tablet |
|
Zykadia (Novartis Pharmaceuticals UK Ltd)
|
|
|
cobimetinib [Specialist drug]
|
Hospital Only
|
NICE TA414
|
|
Oral tablet |
|
Cotellic (Roche Products Ltd)
|
|
|
crizotinib [Specialist drug]
|
Hospital Only
|
NICE TA406
NICE TA422
NICE TA529
|
|
Oral capsule |
|
Xalkori (Pfizer Ltd)
|
|
|
dabrafenib [Specialist drug]
|
Hospital Only
|
NICE TA321
NICE TA396
NICE TA544
NICE TA898
|
|
Oral capsule |
|
Tafinlar (Novartis Pharmaceuticals UK Ltd)
|
|
|
dacomitinib [Specialist drug]
|
|
NICE TA595
|
|
Oral tablet |
|
Vizimpro (Pfizer Ltd)
|
|
|
dasatinib [Specialist drug]
|
Hospital Only
|
NICE TA426
NICE TA425
|
|
Oral suspension |
|
Sprycel (Imported (Germany))
|
|
|
Oral tablet |
|
Dasatinib (Non-proprietary)
|
|
|
Sprycel (Bristol-Myers Squibb Pharmaceuticals Ltd)
|
|
|
encorafenib [Specialist drug]
|
Hospital Only
|
NICE TA562
NICE TA668
|
|
Oral capsule |
|
Braftovi (Pierre Fabre Ltd)
|
|
|
entrectinib [Specialist drug]
|
|
NICE TA643
NICE TA644
|
|
Oral capsule |
|
Rozlytrek (Roche Products Ltd)
|
|
|
erlotinib [Specialist drug]
|
Hospital Only
|
NICE TA227
NICE TA258
NICE TA374
NICE TA374
|
|
Oral tablet |
|
Erlotinib (Non-proprietary)
|
|
|
Tarceva (Roche Products Ltd)
|
|
|
everolimus
|
Hospital Only
|
NICE TA421
NICE TA432
NICE TA449
|
|
Afinitor® NICE TA498
Certican® NICE TA348
Certican® NICE TA481
|
|
Dispersible tablet |
|
Votubia (Novartis Pharmaceuticals UK Ltd)
|
|
|
Oral tablet |
|
Everolimus (Non-proprietary)
|
|
|
Afinitor (Novartis Pharmaceuticals UK Ltd)
|
|
|
Certican (Novartis Pharmaceuticals UK Ltd)
|
|
|
Votubia (Novartis Pharmaceuticals UK Ltd)
|
|
|
fedratinib [Specialist drug]
|
|
NICE TA756
|
|
Oral capsule |
|
Inrebic (Bristol-Myers Squibb Pharmaceuticals Ltd)
|
|
|
gefitinib [Specialist drug]
|
Hospital Only
|
NICE TA192
NICE TA374
|
|
Oral tablet |
|
Gefitinib (Non-proprietary)
|
|
|
Iressa (AstraZeneca UK Ltd)
|
|
|
gilteritinib [Specialist drug]
|
|
NICE TA642
|
|
Oral tablet |
|
Xospata (Astellas Pharma Ltd)
|
|
|
glasdegib [Specialist drug]
|
|
|
|
Oral tablet |
|
Daurismo (Pfizer Ltd)
|
|
|
ibrutinib [Specialist drug]
|
Hospital Only
|
NICE TA429
NICE TA891
NICE TA502
NICE TA795
|
|
Oral tablet |
|
Imbruvica (Janssen-Cilag Ltd)
|
|
|
idelalisib [Specialist drug]
|
Hospital Only
|
NICE TA359
NICE TA604
|
|
Oral tablet |
|
Zydelig (Gilead Sciences Ltd)
|
|
|
imatinib [Specialist drug]
|
Hospital Only
|
NICE TA326
NICE TA70
NICE TA86
NICE TA209
NICE TA426
NICE TA425
|
|
Oral tablet |
|
Imatinib (Non-proprietary)
|
|
|
Glivec (Novartis Pharmaceuticals UK Ltd)
|
|
|
ivosidenib [Specialist drug]
|
|
NICE TA948
NICE TA979
|
|
Oral tablet |
|
Tibsovo (Servier Laboratories Ltd)
|
|
|
ixazomib [Specialist drug]
|
Hospital Only
|
NICE TA870
|
|
Oral capsule |
|
Ninlaro (Takeda UK Ltd)
|
|
|
lapatinib [Specialist drug]
|
Off Formulary
|
NICE TA257
|
|
LAPATINIB
Please note: This medicine is HOSPITAL ONLY.
|
|
|
Oral tablet |
|
Tyverb (Novartis Pharmaceuticals UK Ltd)
|
|
|
larotrectinib [Specialist drug]
|
|
NICE TA630
|
|
Oral solution |
|
Vitrakvi (Bayer Plc)
|
|
|
Oral capsule |
|
Vitrakvi (Bayer Plc)
|
|
|
lenvatinib [Specialist drug]
|
Hospital Only
|
NICE TA535
NICE TA551
NICE TA498
NICE TA858
NICE TA904
|
|
Oral capsule |
|
Kisplyx (Eisai Ltd)
|
|
|
Lenvima (Eisai Ltd)
|
|
|
lorlatinib [Specialist drug]
|
|
NICE TA628
NICE TA909
|
|
Oral tablet |
|
Lorviqua (Pfizer Ltd)
|
|
|
midostaurin [Specialist drug]
|
Hospital Only
|
NICE TA523
NICE TA728
|
|
Oral capsule |
|
Rydapt (Novartis Pharmaceuticals UK Ltd)
|
|
|
mobocertinib [Specialist drug]
|
|
NICE TA855
|
|
momelotinib [Specialist drug]
|
|
NICE TA957
|
|
Oral tablet |
|
Omjjara (GlaxoSmithKline UK Ltd)
|
|
|
neratinib [Specialist drug]
|
|
NICE TA612
|
|
Oral tablet |
|
Nerlynx (Pierre Fabre Ltd)
|
|
|
nilotinib [Specialist drug]
|
Hospital Only
|
NICE TA426
NICE TA425
|
|
Oral capsule |
|
Tasigna (Novartis Pharmaceuticals UK Ltd)
|
|
|
nintedanib
|
Hospital Only
|
NICE TA347
NICE TA379
NICE TA864
NICE TA747
|
|
Nintedanib for use in IPF
This can only be initiated by a specialist IPF center.
Barts health is not commissioned as a IPF center by NHSE.
|
|
|
Oral capsule |
|
Ofev (Boehringer Ingelheim Ltd)
|
|
|
Vargatef (Boehringer Ingelheim Ltd)
|
|
|
niraparib [Specialist drug]
|
Hospital Only
|
NICE TA673
NICE TA784
|
|
Oral capsule |
|
Zejula (GlaxoSmithKline UK Ltd)
|
|
|
olaparib [Specialist drug]
|
Hospital Only
|
NICE TA908
NICE TA946
NICE TA962
NICE TA886
NICE TA887
NICE TA951
|
|
Oral tablet |
|
Lynparza (AstraZeneca UK Ltd)
|
|
|
osimertinib [Specialist drug]
|
Hospital Only
|
NICE TA653
NICE TA654
NICE TA761
|
|
Oral tablet |
|
Tagrisso (AstraZeneca UK Ltd)
|
|
|
palbociclib [Specialist drug]
|
Hospital Only
|
NICE TA495
NICE TA836
|
|
Oral tablet |
|
Ibrance (Pfizer Ltd)
|
|
|
pazopanib [Specialist drug]
|
Hospital Only
|
NICE TA215
|
|
Oral tablet |
|
Votrient (Novartis Pharmaceuticals UK Ltd)
|
|
|
pemigatinib [Specialist drug]
|
|
NICE TA722
|
|
Oral tablet |
|
Pemazyre (Incyte Biosciences UK Ltd)
|
|
|
ponatinib [Specialist drug]
|
Hospital Only
|
NICE TA451
|
|
Oral tablet |
|
Ponatinib (Non-proprietary)
|
|
|
pralsetinib [Specialist drug]
|
|
NICE TA812
|
|
Oral capsule |
|
Gavreto (Roche Products Ltd)
|
|
|
quizartinib [Specialist drug]
|
|
|
|
Oral tablet |
|
Vanflyta (Daiichi Sankyo UK Ltd)
|
|
|
regorafenib [Specialist drug]
|
Hospital Only
|
NICE TA488
NICE TA555
NICE TA866
|
|
Oral tablet |
|
Stivarga (Bayer Plc)
|
|
|
ribociclib [Specialist drug]
|
Hospital Only
|
NICE TA496
NICE TA687
|
|
Oral tablet |
|
Kisqali (Novartis Pharmaceuticals UK Ltd)
|
|
|
ripretinib [Specialist drug]
|
|
NICE TA881
|
|
Oral tablet |
|
Qinlock (Deciphera Pharmaceuticals (Netherlands) B.V.)
|
|
|
rucaparib [Specialist drug]
|
Hospital Only
|
NICE TA611
|
|
Oral tablet |
|
Rubraca (pharmaand GmbH)
|
|
|
ruxolitinib [Specialist drug]
|
Hospital Only
|
NICE TA386
NICE TA921
|
|
Oral tablet |
|
Jakavi (Novartis Pharmaceuticals UK Ltd)
|
|
|
selinexor [Specialist drug]
|
|
NICE TA970
NICE TA974
|
|
Oral tablet |
|
Selinexor (Non-proprietary)
|
|
|
Nexpovio (Menarini Stemline UK Ltd)
|
|
|
selpercatinib [Specialist drug]
|
|
NICE TA742
NICE TA760
NICE TA911
|
|
Oral capsule |
|
Retsevmo (Eli Lilly and Company Ltd)
|
|
|
sorafenib [Specialist drug]
|
Hospital Only
|
NICE TA178
NICE TA474
NICE TA535
|
|
Oral tablet |
|
Sorafenib (Non-proprietary)
|
|
|
Nexavar (Bayer Plc)
|
|
|
sotorasib [Specialist drug]
|
|
NICE TA781
|
|
Oral tablet |
|
Lumykras (Amgen Ltd)
|
|
|
sunitinib [Specialist drug]
|
Hospital Only
|
NICE TA169
NICE TA179
NICE TA178
NICE TA449
|
|
Oral capsule |
|
Sunitinib (Non-proprietary)
|
|
|
Sutent (Pfizer Ltd)
|
|
|
talazoparib [Specialist drug]
|
|
NICE TA952
|
|
Oral capsule |
|
Talazoparib (Non-proprietary)
|
|
|
Talzenna (Pfizer Ltd)
|
|
|
tebentafusp [Specialist drug]
|
|
|
|
Solution for infusion |
|
Kimmtrak (Immunocore Ltd)
|
|
|
temsirolimus [Specialist drug]
|
Hospital Only
|
NICE TA178
|
|
Solution for infusion |
|
Torisel (Pfizer Ltd)
|
|
|
tepotinib [Specialist drug]
|
|
NICE TA789
|
|
Oral tablet |
|
Tepmetko (Merck Serono Ltd)
|
|
|
tivozanib [Specialist drug]
|
Hospital Only
|
NICE TA512
|
|
Oral capsule |
|
Fotivda (Recordati UK Ltd)
|
|
|
trametinib [Specialist drug]
|
Hospital Only
|
NICE TA396
NICE TA544
|
|
Oral tablet |
|
Mekinist (Novartis Pharmaceuticals UK Ltd)
|
|
|
tucatinib [Specialist drug]
|
|
NICE TA786
|
|
Oral tablet |
|
Tukysa (Pfizer Ltd)
|
|
|
vandetanib [Specialist drug]
|
Hospital Only
|
NICE TA550
|
|
Oral tablet |
|
Caprelsa (Sanofi)
|
|
|
vemurafenib [Specialist drug]
|
Hospital Only
|
NICE TA269
|
|
Oral tablet |
|
Zelboraf (Roche Products Ltd)
|
|
|
venetoclax [Specialist drug]
|
Hospital Only
|
NICE TA561
NICE TA663
NICE TA796
NICE TA765
NICE TA787
|
|
Oral tablet |
|
Venclyxto (AbbVie Ltd)
|
|
|
vismodegib [Specialist drug]
|
Off Formulary
|
NICE TA489
|
|
Vismodegib Prescribing
|
|
|
Oral capsule |
|
Erivedge (Roche Products Ltd)
|
|
|
zanubrutinib [Specialist drug]
|
|
NICE TA833
NICE TA931
|
|
Oral capsule |
|
Brukinsa (BeiGene UK Ltd)
|
|
Malignant disease
/ Cytotoxic responsive malignancy
|
|
DACTINOMYCIN
|
Hospital Only
|
|
|
amsacrine [Specialist drug]
|
|
|
|
arsenic trioxide [Specialist drug]
|
Hospital Only
|
NICE TA526
|
|
Solution for infusion |
|
Arsenic trioxide (Non-proprietary)
|
|
|
Trisenox (Teva UK Ltd)
|
|
|
asparaginase [Specialist drug]
|
Hospital Only
|
|
|
Powder for solution for infusion |
|
Spectrila (medac UK)
|
|
|
azacitidine [Specialist drug]
|
Hospital Only
|
NICE TA218
NICE TA399
NICE TA827
|
|
Powder for suspension for injection |
|
Azacitidine (Non-proprietary)
|
|
|
Vidaza (Bristol-Myers Squibb Pharmaceuticals Ltd)
|
|
|
Oral tablet |
|
Onureg (Bristol-Myers Squibb Pharmaceuticals Ltd)
|
|
|
bendamustine hydrochloride [Specialist drug]
|
Hospital Only
|
NICE TA216
NICE TA472
|
|
BENDAMUSTINE HYDROCHLORIDE
HOSPITAL ONLY
|
|
|
Powder for solution for infusion |
|
Bendamustine hydrochloride (Non-proprietary)
|
|
|
bexarotene [Specialist drug]
|
Off Formulary
|
|
|
BEXAROTENE
HOSPITAL ONLY
|
|
|
Oral capsule |
|
Bexarotene (Non-proprietary)
|
|
|
Targretin (Eisai Ltd)
|
|
|
bleomycin [Specialist drug]
|
Hospital Only
|
|
|
Bleomycin monitoring algorithm
Bleomycin monitoring algorithm
|
|
|
Bleomycin for lymphangioma
The JPG supported the use of bleomycin as sclerotherapy for treatment of lymphovenous malformations for adults. Protocol to follow.
|
|
|
Powder for solution for injection |
|
Bleomycin (Non-proprietary)
|
|
|
busulfan [Specialist drug]
|
Hospital Only
|
|
|
Solution for infusion |
|
Busulfan (Non-proprietary)
|
|
|
Oral tablet |
|
Busulfan (Non-proprietary)
|
|
|
cabazitaxel [Specialist drug]
|
Hospital Only
|
NICE TA391
|
|
Solution for infusion |
|
Cabazitaxel (Non-proprietary)
|
|
|
capecitabine [Specialist drug]
|
Hospital Only
|
NICE TA263
NICE TA212
NICE TA191
NICE TA61
NICE TA100
|
|
Oral tablet |
|
Capecitabine (Non-proprietary)
|
|
|
carboplatin [Specialist drug]
|
Hospital Only
|
NICE TA284
NICE TA285
|
|
Solution for infusion |
|
Carboplatin (Non-proprietary)
|
|
|
carmustine [Specialist drug]
|
Hospital Only
|
NICE TA121
|
|
Prolonged-release intralesional implant |
|
Gliadel (Clinigen Healthcare Ltd)
|
|
|
chlorambucil [Specialist drug]
|
Hospital Only
|
NICE TA343
NICE TA344
|
|
Oral tablet |
|
Chlorambucil (Non-proprietary)
|
|
|
chlormethine [Specialist drug]
|
|
NICE TA720
|
|
Cutaneous gel |
|
Ledaga (Recordati Rare Diseases UK Ltd)
|
|
|
cisplatin [Specialist drug]
|
Hospital Only
|
|
|
Solution for infusion |
|
Cisplatin (Non-proprietary)
|
|
|
cladribine
|
Hospital Only
|
NICE TA616
|
|
Solution for injection |
|
Litak (Lipomed GmbH)
|
|
|
Solution for infusion |
|
Leustat (Atnahs Pharma UK Ltd)
|
|
|
Oral tablet |
|
Mavenclad (Merck Serono Ltd)
|
|
|
clofarabine [Specialist drug]
|
Hospital Only
|
|
|
Solution for infusion |
|
Clofarabine (Non-proprietary)
|
|
|
crisantaspase [Specialist drug]
|
Off Formulary
|
|
|
Powder for solution for injection |
|
Erwinase (Porton Biopharma Ltd)
|
|
|
cyclophosphamide
|
Hospital Only
|
|
|
Powder for solution for injection |
|
Cyclophosphamide (Non-proprietary)
|
Hospital Only
|
|
Cyclophosphamide
For Hospital Use Only
|
|
|
Oral tablet |
|
Cyclophosphamide (Non-proprietary)
|
|
|
Cytoxan (Imported (United States))
|
|
|
cytarabine [Specialist drug]
|
Hospital Only
|
|
|
Solution for injection |
|
Cytarabine (Non-proprietary)
|
|
|
dacarbazine [Specialist drug]
|
Hospital Only
|
|
|
Powder for solution for injection |
|
Dacarbazine (Non-proprietary)
|
On Formulary
|
|
Powder for solution for infusion |
|
Dacarbazine (Non-proprietary)
|
|
|
daunorubicin [Specialist drug]
|
Hospital Only
|
|
|
Powder for solution for infusion |
|
Daunorubicin (Non-proprietary)
|
|
|
daunorubicin with cytarabine [Specialist drug]
|
Hospital Only
|
NICE TA552
|
|
Powder for solution for infusion |
|
Vyxeos (Jazz Pharmaceuticals UK Ltd)
|
|
|
decitabine [Specialist drug]
|
Hospital Only
|
|
|
Powder for solution for infusion |
|
Dacogen (Janssen-Cilag Ltd)
|
|
|
decitabine with cedazuridine [Specialist drug]
|
|
|
|
Oral tablet |
|
Inaqovi (Otsuka Pharmaceuticals (U.K.) Ltd)
|
|
|
docetaxel [Specialist drug]
|
Hospital Only
|
NICE TA101
NICE TA509
|
|
Solution for infusion |
|
Docetaxel (Non-proprietary)
|
|
|
doxorubicin hydrochloride [Specialist drug]
|
Hospital Only
|
NICE TA389
NICE TA465
|
|
Solution for injection |
|
Doxorubicin hydrochloride (Non-proprietary)
|
|
|
Solution for infusion |
|
Doxorubicin hydrochloride (Non-proprietary)
|
|
|
epirubicin hydrochloride [Specialist drug]
|
Hospital Only
|
|
|
Solution for injection |
|
Epirubicin hydrochloride (Non-proprietary)
|
|
|
Pharmorubicin (Pfizer Ltd)
|
|
|
Solution for infusion |
|
Epirubicin hydrochloride (Non-proprietary)
|
|
|
eribulin [Specialist drug]
|
Hospital Only
|
NICE TA423
NICE TA515
|
|
Solution for injection |
|
Halaven (Eisai Ltd)
|
|
|
estramustine phosphate [Specialist drug]
|
Off Formulary
|
|
|
etoposide [Specialist drug]
|
Hospital Only
|
|
|
Powder for solution for injection |
|
Etopophos (Neon Healthcare Ltd)
|
On Formulary
|
|
Vinca alkaloids and etoposide
HOSPITAL ONLY PLEASE REFER TO FULL CHEMOTHERAPY GUIDELINES
|
|
|
Solution for infusion |
|
Etoposide (Non-proprietary)
|
On Formulary
|
|
Vinca alkaloids and etoposide
HOSPITAL ONLY PLEASE REFER TO FULL CHEMOTHERAPY GUIDELINES
|
|
|
Oral capsule |
|
Etoposide (Non-proprietary)
|
|
|
fludarabine phosphate [Specialist drug]
|
Hospital Only
|
NICE TA119
NICE TA29
|
|
Solution for injection |
|
Fludarabine phosphate (Non-proprietary)
|
|
|
Powder for solution for injection |
|
Fludarabine phosphate (Non-proprietary)
|
|
|
Fludara (Sanofi)
|
|
|
Oral tablet |
|
Fludara (Sanofi)
|
|
|
fluorouracil
|
Hospital Only
|
|
|
Solution for injection |
|
Fluorouracil (Non-proprietary)
|
|
|
Solution for infusion |
|
Fluorouracil (Non-proprietary)
|
|
|
Cutaneous cream |
|
Fluorouracil (Non-proprietary)
|
|
|
Efudix (Viatris UK Healthcare Ltd)
|
|
|
gemcitabine [Specialist drug]
|
Hospital Only
|
NICE TA25
NICE TA116
NICE TA285
NICE TA389
NICE TA476
|
|
Solution for infusion |
|
Gemcitabine (Non-proprietary)
|
|
|
Powder for solution for infusion |
|
Gemcitabine (Non-proprietary)
|
|
|
hydroxycarbamide
|
Hospital Only
|
|
|
HOSPITAL ONLY
EXCEPT AS PART OF SHARED CARE
|
|
|
Hydroxyurea shared care guidance
HYDROXYCARBAMIDE (HYDROXYUREA) For the Management of Sickle Cell Disease in Adults and Children
|
|
|
Oral solution |
|
Xromi (Nova Laboratories Ltd)
|
|
|
Oral tablet |
|
Siklos (Masters Pharmaceuticals Ltd)
|
|
|
Oral capsule |
|
Hydroxycarbamide (Non-proprietary)
|
|
|
Droxia (Imported (United States))
|
|
|
Hydrea (Neon Healthcare Ltd)
|
|
|
idarubicin hydrochloride [Specialist drug]
|
Hospital Only
|
|
|
Oral capsule |
|
Zavedos (Pfizer Ltd)
|
|
|
ifosfamide [Specialist drug]
|
Hospital Only
|
|
|
Powder for solution for injection |
|
Ifosfamide (Non-proprietary)
|
On Formulary
|
|
Ifosfamide
For Hospital Use Only
|
|
|
irinotecan hydrochloride [Specialist drug]
|
Hospital Only
|
NICE TA440
|
|
Solution for infusion |
|
Irinotecan hydrochloride (Non-proprietary)
|
|
|
Campto (Pfizer Ltd)
|
|
|
Dispersion for infusion |
|
Onivyde (Servier Laboratories Ltd)
|
|
|
lomustine [Specialist drug]
|
Hospital Only
|
|
|
Oral capsule |
|
Lomustine (Non-proprietary)
|
|
|
melphalan [Specialist drug]
|
Hospital Only
|
|
|
Powder and solvent for solution for injection |
|
Melphalan (Non-proprietary)
|
Hospital Only
|
|
Oral tablet |
|
Melphalan (Non-proprietary)
|
|
|
mercaptopurine
|
Hospital Only
|
|
|
IBD Shared Care Guidelines 2019
IBD Shared Care Guidelines
|
|
|
Oral suspension |
|
Xaluprine (Nova Laboratories Ltd)
|
|
|
Oral tablet |
|
Mercaptopurine (Non-proprietary)
|
|
|
Hanixol (Fontus Health Ltd)
|
|
|
methotrexate
|
Hospital Only
|
|
|
IBD Shared Care Guidelines 2019
IBD Shared Care Guidelines
|
|
|
Methotrexate oral: Trust Policy
see attached
|
|
|
Oral solution |
|
Methotrexate (Non-proprietary)
|
|
|
Jylamvo (Esteve Pharmaceuticals Ltd)
|
|
|
Solution for injection |
|
Methotrexate (Non-proprietary)
|
|
|
Methofill (Accord-UK Ltd)
|
|
|
Metoject PEN (medac UK)
|
|
|
Nordimet (Nordic Pharma Ltd)
|
|
|
Zlatal (Nordic Pharma Ltd)
|
|
|
Solution for infusion |
|
Methotrexate (Non-proprietary)
|
|
|
Oral tablet |
|
Methotrexate (Non-proprietary)
|
|
|
Maxtrex (Pfizer Ltd)
|
|
|
mitomycin [Specialist drug]
|
Hospital Only
|
|
|
Mitomycin Proforma
|
|
|
Powder for solution for injection |
|
Mitomycin (Non-proprietary)
|
|
|
Mitocin (Vygoris Ltd)
|
|
|
Powder and solvent for intravesical solution |
|
Mitomycin (Non-proprietary)
|
|
|
mitotane [Specialist drug]
|
Hospital Only
|
|
|
Oral tablet |
|
Lysodren (Esteve RD UK & Ireland Ltd)
|
|
|
mitoxantrone [Specialist drug]
|
Hospital Only
|
|
|
Solution for infusion |
|
Onkotrone (Baxter Healthcare Ltd)
|
|
|
nelarabine [Specialist drug]
|
Hospital Only
|
|
|
Solution for infusion |
|
Atriance (Sandoz Ltd)
|
|
|
oxaliplatin [Specialist drug]
|
Hospital Only
|
NICE TA100
NICE TA93
|
|
Solution for infusion |
|
Oxaliplatin (Non-proprietary)
|
|
|
paclitaxel [Specialist drug]
|
Hospital Only
|
NICE TA55
NICE TA284
NICE TA389
NICE TA476
|
|
Solution for infusion |
|
Paclitaxel (Non-proprietary)
|
|
|
Powder for suspension for infusion |
|
Abraxane (Bristol-Myers Squibb Pharmaceuticals Ltd)
|
|
|
panobinostat [Specialist drug]
|
Hospital Only
|
NICE TA380
|
|
Oral capsule |
|
Farydak (pharmaand GmbH)
|
|
|
pegaspargase [Specialist drug]
|
Hospital Only
|
NICE TA408
|
|
Powder for solution for injection |
|
Oncaspar (Servier Laboratories Ltd)
|
|
|
pemetrexed [Specialist drug]
|
Hospital Only
|
NICE TA124
NICE TA181
NICE TA402
NICE TA190
NICE TA135
|
|
Solution for infusion |
|
Pemetrexed (Non-proprietary)
|
|
|
Powder for solution for infusion |
|
Pemetrexed (Non-proprietary)
|
|
|
Alimta (Eli Lilly and Company Ltd)
|
|
|
pentostatin [Specialist drug]
|
Hospital Only
|
|
|
Powder for solution for injection |
|
Nipent (Pfizer Ltd)
|
|
|
pixantrone [Specialist drug]
|
Hospital Only
|
NICE TA306
|
|
Powder for solution for infusion |
|
Pixuvri (Servier Laboratories Ltd)
|
|
|
procarbazine [Specialist drug]
|
Hospital Only
|
|
|
Oral capsule |
|
Procarbazine (Non-proprietary)
|
|
|
raltitrexed [Specialist drug]
|
Hospital Only
|
|
|
Powder for solution for infusion |
|
Tomudex (Pfizer Ltd)
|
|
|
ropeginterferon alfa-2b [Specialist drug]
|
|
|
|
Solution for injection |
|
Besremi (AOP Orphan Ltd)
|
|
|
streptozocin [Specialist drug]
|
Hospital Only
|
|
|
Powder for solution for infusion |
|
Zanosar (Esteve Pharmaceuticals Ltd)
|
|
|
tegafur with gimeracil and oteracil [Specialist drug]
|
Hospital Only
|
|
|
temozolomide [Specialist drug]
|
Hospital Only
|
NICE TA23
NICE TA121
|
|
Oral capsule |
|
Temozolomide (Non-proprietary)
|
|
|
Temodal (Merck Sharp & Dohme (UK) Ltd)
|
|
|
thiotepa [Specialist drug]
|
Hospital Only
|
|
|
Powder for solution for infusion |
|
Thiotepa (Non-proprietary)
|
|
|
Tepadina (Adienne Pharma & Biotech)
|
|
|
tioguanine [Specialist drug]
|
Hospital Only
|
|
|
Oral tablet |
|
Tioguanine (Non-proprietary)
|
|
|
topotecan [Specialist drug]
|
Hospital Only
|
NICE TA183
NICE TA184
NICE TA389
|
|
June 2024 - Topotecan intravitreal injection – elevated doses in the treatment of paediatric retinoblastoma patients in BH
Topotecan intravitreal injection approved at NEL FPG for elevated doses in the treatment of paediatric retinoblastoma patients in Barts Health
Formulary Status: Hospital Only
|
|
|
Solution for infusion |
|
Topotecan (Non-proprietary)
|
|
|
Oral capsule |
|
Hycamtin (Sandoz Ltd)
|
|
|
trabectedin [Specialist drug]
|
Hospital Only
|
NICE TA185
NICE TA389
|
|
Powder for solution for infusion |
|
Trabectedin (Non-proprietary)
|
|
|
Yondelis (Immedica Pharma AB)
|
|
|
treosulfan [Specialist drug]
|
Hospital Only
|
NICE TA640
|
|
Powder for solution for injection |
|
Treosulfan (Non-proprietary)
|
On Formulary
|
|
Trecondi (medac UK)
|
|
|
tretinoin [Specialist drug]
|
Hospital Only
|
|
|
Oral capsule |
|
Tretinoin (Non-proprietary)
|
|
|
trifluridine with tipiracil [Specialist drug]
|
Hospital Only
|
NICE TA405
NICE TA852
|
|
Oral tablet |
|
Lonsurf (Servier Laboratories Ltd)
|
|
|
vinblastine sulfate [Specialist drug]
|
Hospital Only
|
|
|
Solution for injection |
|
Vinblastine sulfate (Non-proprietary)
|
|
|
vincristine sulfate [Specialist drug]
|
Hospital Only
|
|
|
Solution for injection |
|
Vincristine sulfate (Non-proprietary)
|
|
|
vindesine sulfate [Specialist drug]
|
Hospital Only
|
|
|
Powder for solution for injection |
|
Eldisine (Genus Pharmaceuticals Ltd)
|
|
|
vinorelbine [Specialist drug]
|
Hospital Only
|
|
|
Solution for infusion |
|
Vinorelbine (Non-proprietary)
|
|
|
Navelbine (Pierre Fabre Ltd)
|
|
|
Oral capsule |
|
Vinorelbine (Non-proprietary)
|
|
|
Navelbine (Pierre Fabre Ltd)
|
|
Malignant disease
/ Cytotoxic drug-induced side effects
|
|
dexrazoxane
|
Off Formulary
|
|
|
Powder for solution for infusion |
|
Cardioxane (CNX Therapeutics Ltd)
|
|
|
Powder and solvent for solution for infusion |
|
Savene (Clinigen Healthcare Ltd)
|
|
|
folinic acid
|
Hospital Only
|
NICE TA212
|
|
Solution for injection |
|
Folinic acid (Non-proprietary)
|
Hospital Only
|
|
Antidotes List
see attached
|
|
|
Sodiofolin (medac UK)
|
|
|
Oral tablet |
|
Folinic acid (Non-proprietary)
|
|
|
Refolinon (Pfizer Ltd)
|
|
|
glucarpidase
|
|
|
|
Powder for solution for injection |
|
Voraxaze (Protherics Medicines Development Ltd)
|
|
|
levofolinic acid
|
Hospital Only
|
|
|
Solution for injection |
|
Levofolinic acid (Non-proprietary)
|
|
|
Isovorin (Pfizer Ltd)
|
|
|
mesna
|
Hospital Only
|
|
|
Solution for injection |
|
Mesna (Non-proprietary)
|
Hospital Only
|
|
Mesna
For Hospital Use Only
|
|
|
Oral tablet |
|
Mesna (Non-proprietary)
|
|
Malignant disease
/ Hyperuricaemia associated with cytotoxic drugs
|
|
allopurinol
|
On Formulary
|
|
|
Oral tablet |
|
Allopurinol (Non-proprietary)
|
|
|
Zyloric (Aspen Pharma Trading Ltd)
|
|
|
febuxostat
|
On Formulary
|
NICE TA164
|
|
Oral tablet |
|
Febuxostat (Non-proprietary)
|
|
|
Adenuric (A. Menarini Farmaceutica Internazionale SRL)
|
|
|
Elstabya (Amarox Ltd)
|
|
|
rasburicase
|
On Formulary
|
|
|
Powder and solvent for solution for infusion |
|
Fasturtec (Sanofi)
|
On Formulary
|
|
Fasturtec®
For Hospital Use Only
|
|
Malignant disease
/ Hormone responsive malignancy
|
|
abiraterone acetate
|
Hospital Only
|
NICE TA259
NICE TA387
NICE TA721
|
|
Oral tablet |
|
Abiraterone acetate (Non-proprietary)
|
|
|
Zytiga (Janssen-Cilag Ltd)
|
|
|
apalutamide
|
|
NICE TA740
NICE TA741
|
|
Oral tablet |
|
Apalutamide (Non-proprietary)
|
|
|
Erleada (Janssen-Cilag Ltd)
|
|
|
bicalutamide
|
On Formulary
|
|
|
Oral tablet |
|
Bicalutamide (Non-proprietary)
|
|
|
Casodex (AstraZeneca UK Ltd)
|
|
|
buserelin
|
Hospital Only
|
|
|
Solution for injection |
|
Buserelin (Non-proprietary)
|
|
|
Suprefact (Neon Healthcare Ltd)
|
|
|
Spray |
|
Suprecur (Neon Healthcare Ltd)
|
|
|
cyproterone acetate
|
On Formulary
|
|
|
Oral tablet |
|
Cyproterone acetate (Non-proprietary)
|
|
|
Androcur (Bayer Plc)
|
|
|
Cyprostat (Bayer Plc)
|
|
|
darolutamide
|
|
NICE TA660
NICE TA903
|
|
Oral tablet |
|
Nubeqa (Bayer Plc)
|
|
|
degarelix
|
On Formulary
|
NICE TA404
|
|
Degarelix shared care guideline
Degarelix
|
|
|
Powder and solvent for solution for injection |
|
Firmagon (Ferring Pharmaceuticals Ltd)
|
On Formulary
|
|
Degarelix shared care guideline
|
|
|
diethylstilbestrol
|
On Formulary
|
|
|
Oral tablet |
|
Diethylstilbestrol (Non-proprietary)
|
|
|
enzalutamide
|
Hospital Only
|
NICE TA316
NICE TA377
NICE TA580
NICE TA712
|
|
Notes
Patient Information when used in Malignancy
|
|
|
Oral tablet |
|
Xtandi (Astellas Pharma Ltd)
|
|
|
ethinylestradiol
|
Off Formulary
|
|
|
flutamide
|
On Formulary
|
|
|
Oral tablet |
|
Flutamide (Non-proprietary)
|
|
|
goserelin
|
On Formulary
|
|
|
GOSERELIN
FOR HOSPITAL USE ONLY for All indications except for treatment of prostate cancer Used for endometriosis and fibroids
|
|
|
Proformas
|
|
|
Prolonged-release subcutaneous implant |
|
Zoladex (AstraZeneca UK Ltd)
|
|
|
Zoladex LA (AstraZeneca UK Ltd)
|
|
|
lanreotide
|
Hospital Only
|
|
|
Lanreotide
-
Lanreotide Autogel (Somatuline Autogel) is a licensed long-acting somatostatin analogue used in treatment of Acromegaly to relieve symptoms in patients with carcinoid tumors.
-
There is also lanreotide LA which is shorter acting – and not kept in pharmacy
|
|
|
Solution for injection |
|
Lanreotide (Non-proprietary)
|
|
|
Somatuline Autogel (Ipsen Ltd)
|
Hospital Only
|
|
Lanreotide
- Lanreotide Autogel (Somatuline Autogel) is a licensed long-acting somatostatin analogue used in treatment of Acromegaly to relieve symptoms in patients with carcinoid tumors.
- There is also lanreotide LA which is shorter acting – and not kept in pharmacy
|
|
|
Note:
For HOSPITAL use only
|
|
|
leuprorelin acetate
|
Hospital Only
|
|
|
Powder and solvent for suspension for injection |
|
Prostap 3 DCS (Takeda UK Ltd)
|
On Formulary
|
|
Prostap® 3 DCS
Endometriosis and fibroids (un-licensed)
|
|
|
Prostap SR DCS (Takeda UK Ltd)
|
On Formulary
|
|
Prolonged-release subcutaneous implant |
|
Staladex (Aspire Pharma Ltd)
|
|
|
medroxyprogesterone acetate
|
On Formulary
|
|
|
Suspension for injection |
|
Depo-Provera (Pfizer Ltd)
|
Hospital Only
|
|
Sayana Press (Pfizer Ltd)
|
|
|
Medroxyprogesterone acetate subcutaneous injection
Sayana Press - the SC form of medroxyprogesterone acetate - is on formulary for patients who are willing and able to self administer the injection. It is an alternative to the intramuscular form.
|
|
|
Oral tablet |
|
Provera (Pfizer Ltd)
|
|
|
megestrol acetate
|
On Formulary
|
|
|
Oral suspension |
|
Megestrol acetate (Non-proprietary)
|
|
|
Oral tablet |
|
Megestrol acetate (Non-proprietary)
|
|
|
Megace (Bausch & Lomb UK Ltd)
|
|
|
norethisterone
|
Hospital Only
|
|
|
Solution for injection |
|
Noristerat (Bayer Plc)
|
|
|
Oral tablet |
|
Norethisterone (Non-proprietary)
|
|
|
Noriday (Pfizer Ltd)
|
|
|
Primolut N (Bayer Plc)
|
|
|
Utovlan (Pfizer Ltd)
|
|
|
octreotide
|
Hospital Only
|
|
|
Octreotide LAR
- Octreotide is a licensed long acting somatostation analogue used in the treatment of acromegaly & neuroendocrine neoplasms. Injections are administered once a month once patients have been converted from regular Octreotide.
|
|
|
OCTREOTIDE
FOR HOSPITAL USE ONLY Used for neuroendocrine tumours (carcinoid syndrome)
|
|
|
Octreotide in pancreatic surgery
|
|
|
Solution for injection |
|
Octreotide (Non-proprietary)
|
Hospital Only
|
|
Octreotide LAR
-
Octreotide is a licensed long acting somatostation analogue used in the treatment of acromegaly & neuroendocrine neoplasms. Injections are administered once a month once patients have been converted from regular Octreotide.
|
|
|
Octreotide in pancreatic surgery
|
|
|
Octreotide
FOR HOSPITAL USE ONLY
|
|
|
Sandostatin (Novartis Pharmaceuticals UK Ltd)
|
Hospital Only
|
|
OCTREOTIDE
FOR HOSPITAL USE ONLY Used for neuroendocrine tumours (carcinoid syndrome)
|
|
|
Octreotide LAR
-
Octreotide is a licensed long acting somatostation analogue used in the treatment of acromegaly & neuroendocrine neoplasms. Injections are administered once a month once patients have been converted from regular Octreotide.
|
|
|
Octreotide in pancreatic surgery
|
|
|
Powder and solvent for suspension for injection |
|
Olatuton (Teva UK Ltd)
|
|
|
Sandostatin LAR (Novartis Pharmaceuticals UK Ltd)
|
Hospital Only
|
|
Octreotide LAR
-
Octreotide is a licensed long acting somatostation analogue used in the treatment of acromegaly & neuroendocrine neoplasms. Injections are administered once a month once patients have been converted from regular Octreotide.
|
|
|
Octreotide in pancreatic surgery
|
|
|
Sandostatin Lar®
FOR HOSPITAL USE ONLY
|
|
|
pasireotide
|
|
|
|
Solution for injection |
|
Signifor (Recordati Rare Diseases UK Ltd)
|
|
|
Powder and solvent for suspension for injection |
|
Signifor (Recordati Rare Diseases UK Ltd)
|
|
|
relugolix
|
|
NICE TA995
|
|
Oral tablet |
|
Orgovyx (Accord-UK Ltd)
|
|
|
triptorelin
|
Hospital Only
|
|
|
Powder and solvent for suspension for injection |
|
Decapeptyl SR (Ipsen Ltd)
|
|
|
Gonapeptyl Depot (Ferring Pharmaceuticals Ltd)
|
|
|
Salvacyl (Ipsen Ltd)
|
|
Malignant disease
/ Hormone responsive breast cancer
|
|
anastrozole
|
On Formulary
|
|
|
Oral tablet |
|
Anastrozole (Non-proprietary)
|
|
|
Arimidex (AstraZeneca UK Ltd)
|
|
|
exemestane
|
On Formulary
|
|
|
Oral tablet |
|
Exemestane (Non-proprietary)
|
|
|
Aromasin (Pfizer Ltd)
|
|
|
fulvestrant
|
On Formulary
|
NICE TA503
|
|
Solution for injection |
|
Fulvestrant (Non-proprietary)
|
|
|
Faslodex (AstraZeneca UK Ltd)
|
On Formulary
|
|
letrozole
|
On Formulary
|
|
|
Oral tablet |
|
Letrozole (Non-proprietary)
|
|
|
Femara (Novartis Pharmaceuticals UK Ltd)
|
|
|
tamoxifen
|
On Formulary
|
|
|
Oral solution |
|
Tamoxifen (Non-proprietary)
|
On Formulary
|
|
Oral tablet |
|
Tamoxifen (Non-proprietary)
|
|
|
toremifene
|
Off Formulary
|
|
|
Oral tablet |
|
Fareston (Orion Pharma (UK) Ltd)
|
|
Malignant disease
/ Photodynamic therapy responsive malignancy
|
|
temoporfin [Specialist drug]
|
Hospital Only
|
|
|
Solution for injection |
|
Foscan (Biolitec Pharma Ltd)
|
|
Malignant disease
/ Secondary bone metastases and hypercalcaemia
|
|
calcitonin (salmon)
|
On Formulary
|
|
|
CALCITONIN (SALMON)/SALCATONIN
IV FORMULATION IS FOR HOSPITAL USE ONLY
|
|
|
Solution for injection |
|
Calcitonin (salmon) (Non-proprietary)
|
Hospital Only
|
|
Calcitonin (salmon)
HOSPITAL ONLY
|
|
|
denosumab
|
Hospital Only
|
NICE TA204
NICE TA265
|
|
HOSPITAL ONLY USE
Skeletal related events in cancer
|
|
|
Osteoporosis in postmenopausal women and in men at increased risk of fractures ( March 2022)
Approved in hospital for secondary prevention of osteoporosis in men and women 60 years or over, who meet the following inclusion criteria:
1. Patients with severe renal impairment.
2. Patients who are intolerant and with contraindications to bisphosphonate therapy.
3. Patients with severe vertebral osteoporosis.
|
|
|
Solution for injection |
|
Denosumab (Non-proprietary)
|
|
|
Prolia (Amgen Ltd)
|
On Formulary
|
|
Xgeva (Amgen Ltd)
|
On Formulary
|
|
ibandronic acid
|
Off Formulary
|
NICE TA464
|
|
IBANDRONIC ACID
IV FORMULATION IS FOR HOSPITAL USE ONLY
|
|
|
Solution for injection |
|
Ibandronic acid (Non-proprietary)
|
|
|
Bonviva (Atnahs Pharma UK Ltd)
|
|
|
Solution for infusion |
|
Ibandronic acid (Non-proprietary)
|
|
|
Bondronat (Atnahs Pharma UK Ltd)
|
|
|
Oral tablet |
|
Ibandronic acid (Non-proprietary)
|
|
|
Bondronat (Atnahs Pharma UK Ltd)
|
|
|
Bonviva (Atnahs Pharma UK Ltd)
|
|
|
Iasibon (Aspire Pharma Ltd)
|
|
|
pamidronate disodium
|
On Formulary
|
|
|
PAMIDRONATE DISODIUM
FOR HOSPITAL USE ONLY Hypercalcaemia-will decrease calcium after 24 hours (5-6 days for the full effect). Effects last 14-21 days
|
|
|
Solution for infusion |
|
Pamidronate disodium (Non-proprietary)
|
On Formulary
|
|
PAMIDRONATE DISODIUM
FOR HOSPITAL USE ONLY Hypercalcaemia-will decrease calcium after 24 hours (5-6 days for the full effect). Effects last 14-21 days
|
|
|
sodium clodronate
|
Hospital Only
|
|
|
Oral tablet |
|
Clasteon (Kent Pharma (UK) Ltd)
|
|
|
Loron (Esteve Pharmaceuticals Ltd)
|
|
|
Oral capsule |
|
Sodium clodronate (Non-proprietary)
|
|
|
Clasteon (Kent Pharma (UK) Ltd)
|
|
|
zoledronic acid
|
Hospital Only
|
NICE TA464
|
|
Infusion |
|
Zoledronic acid (Non-proprietary)
|
|
|
Aclasta (Sandoz Ltd)
|
|
|
Zometa (Phoenix Labs Ltd)
|
On Formulary
|
|
Solution for infusion |
|
Zoledronic acid (Non-proprietary)
|
|
|
Zometa (Phoenix Labs Ltd)
|
On Formulary
|