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Cardiovascular system
Cardiovascular system / Hypertension
  amiloride hydrochloride On Formulary
AMILORIDE HYDROCHLORIDE

Heart failure guidelines
 

https://www.nice.org.uk/guidance/ng106

  Oral solution
Amiloride hydrochloride (Non-proprietary) On Formulary
  amlodipine On Formulary
  atenolol On Formulary
  bendroflumethiazide On Formulary
BENDROFLUMETHIAZIDE

Note: NICE no longer recommends for hypertension (unless in the treatment of the diabetic - see necessary guidelines).

Hypertension guidelines

http://www.nice.org.uk/guidance/CG127

  captopril On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

  carvedilol On Formulary
CARVEDILOL

AF guidelines
 


 
Heart failure guidelines
 
https://www.nice.org.uk/guidance/ng106
 
Hypertension guidelines
 
https://pathways.nice.org.uk/pathways/hypertension
 
Secondary prevention of MI guidelines
https://pathways.nice.org.uk/pathways/myocardial-infarction-rehabilitation-and-preventing-further-cardiovascular-disease

Stable angina guidelines

https://www.nice.org.uk/guidance/cg126

  clonidine hydrochloride On Formulary
Paediatric Premedication Guideline

see attached

CLONIDINE HYDROCHLORIDE

Injection Formulation is for Hospital Use Only

The Association of Paediatric Palliative Medicine Formulary - 2017

see attached

Clonidine use in Paediatrics

Sedation in PICU

Weaning sedation after PICU

 

ADHD is hospital only

 

  Oral solution
Clonidine hydrochloride (Non-proprietary) On Formulary
  Solution for injection
Catapres (Glenwood GmbH) Hospital Only
Note:

Injection Formulation is for Hospital Use Only

  diltiazem hydrochloride On Formulary
  Modified-release tablet
Diltiazem hydrochloride (Non-proprietary) On Formulary
Retalzem (Kent Pharma (UK) Ltd) On Formulary
Tildiem (Sanofi) On Formulary
Tildiem Retard (Sanofi) On Formulary
  doxazosin On Formulary
  Modified-release tablet
Cardura XL (Viatris UK Healthcare Ltd) Off Formulary
Doxadura XL (Dexcel-Pharma Ltd) Off Formulary
Larbex XL (Teva UK Ltd) Off Formulary
Raporsin XL (Accord-UK Ltd) Off Formulary
  enalapril maleate On Formulary
  esmolol hydrochloride On Formulary
  Solution for injection
Esmolol hydrochloride (Non-proprietary) Hospital Only
Brevibloc (Baxter Healthcare Ltd) On Formulary
Brevibloc®

Injection formulation is for Hospital Use Only

  Solution for infusion
Brevibloc (Baxter Healthcare Ltd) On Formulary
Brevibloc®

Injection formulation is for Hospital Use Only

  hydralazine hydrochloride On Formulary
HYDRALAZINE HYDROCHLORIDE

Injection Formulation is for Hospital Use Only

  Powder for solution for injection
Hydralazine hydrochloride (Non-proprietary) Hospital Only
HYDRALAZINE HYDROCHLORIDE

Injection Formulation is for Hospital Use Only

  labetalol hydrochloride On Formulary
LABETALOL HYDROCHLORIDE

Injection Formulation is for Hospital Use Only

AF guidelines
 
https://pathways.nice.org.uk/pathways/atrial-fibrillation
 
Heart failure guidelines
 
https://www.nice.org.uk/guidance/ng106
 
Hypertension guidelines
 
https://pathways.nice.org.uk/pathways/hypertension
 
Secondary prevention of MI guidelines

https://pathways.nice.org.uk/pathways/myocardial-infarction-rehabilitation-and-preventing-further-cardiovascular-disease
 
Stable angina guidelines

http://www.nice.org.uk/guidance/CG126

  Solution for injection
Labetalol hydrochloride (Non-proprietary) On Formulary
Labetalol Hydrochloride

Injection formulation is for Hospital Use Only

  lisinopril On Formulary
  Oral solution
Lisinopril (Non-proprietary) On Formulary
  metolazone On Formulary
  metoprolol tartrate On Formulary
  propranolol hydrochloride On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

  Oral solution
Propranolol hydrochloride (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

  spironolactone On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Agreed standard strengths

Spironolactone

50mg/5ml to be used for all doses of 1mg or higher

10mg/5ml is reserved for neonatal doses under 1mg- not to be used on discharge

 

Spironolactone

Note: Only 50mg/5mL suspension is ON FORMULARY.

SPIRONOLACTONE

For use in heart failure, ascites, hypertension, and nephrotic syndrome.

Heart failure guidelines

https://www.nice.org.uk/guidance/ng106

 
Hypertension guidelines

https://pathways.nice.org.uk/pathways/hypertension

  timolol maleate Off Formulary
  verapamil hydrochloride On Formulary
  Oral solution
Verapamil hydrochloride (Non-proprietary) On Formulary
  Solution for injection
Securon (Viatris UK Healthcare Ltd) On Formulary
Cardiovascular system / Portal hypertension
  propranolol hydrochloride On Formulary
  Oral solution
Propranolol hydrochloride (Non-proprietary) On Formulary
Cardiovascular system / Pulmonary hypertension
  bosentan On Formulary
  epoprostenol Hospital Only
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

  Powder and solvent for solution for infusion
Flolan (GlaxoSmithKline UK Ltd) Hospital Only
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

Note:

Injection formulation is Hospital Use Only

  iloprost On Formulary
ILOPROST

Injection formulation is Hospital Use Only

  Solution for infusion
Iloprost (Non-proprietary) Hospital Only
Iloprost

Injection formulation is Hospital Only

  sildenafil On Formulary
Agreed standard strengths

Sildenafil

Licensed 10mg/ml to be used for all doses of 1mg or higher

20mg/5ml is reserved for neonatal doses under 1mg- not to be used on discharge

NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

  tolazoline On Formulary
TOLAZOLINE

Injection formulation is Hospital Use Only

NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Neonatal Formulary Version 9 2016 Barts Health Dec 2016

Cardiovascular system / Hypertension associated with phaeochromocytoma
  phenoxybenzamine hydrochloride On Formulary
PHENOXYBENZAMINE HYDROCHLORIDE

Injection Formulation is for Hospital Use Only

Cardiovascular system / Hypertensive crises
  hydralazine hydrochloride
  Powder for solution for injection
Hydralazine hydrochloride (Non-proprietary) Hospital Only
  labetalol hydrochloride On Formulary
LABETALOL HYDROCHLORIDE

Injection Formulation is for Hospital Use Only

AF guidelines
 
https://pathways.nice.org.uk/pathways/atrial-fibrillation
 
Heart failure guidelines
 
https://www.nice.org.uk/guidance/ng106
 
Hypertension guidelines
 
https://pathways.nice.org.uk/pathways/hypertension
 
Secondary prevention of MI guidelines

https://pathways.nice.org.uk/pathways/myocardial-infarction-rehabilitation-and-preventing-further-cardiovascular-disease
 
Stable angina guidelines

http://www.nice.org.uk/guidance/CG126

  Solution for injection
Labetalol hydrochloride (Non-proprietary) On Formulary
Labetalol Hydrochloride

Injection formulation is for Hospital Use Only

  sodium nitroprusside On Formulary
SODIUM NITROPRUSSIDE

Injection formulation is Hospital Use Only

  Powder and solvent for solution for infusion
Sodium nitroprusside (Non-proprietary) On Formulary
Sodium Nitroprusside

Injection formulation is Hospital Use Only

Cardiovascular system / Hypotension and shock
  Etilefrine On Formulary
Etilefrine

Approved Indication at Barts Health
Secondary prevention of priapism in adult and paediatric patients with sickle cell disease (unlicensed)

Paediatric patients -                0.5mg/kg at night OR 0.25mg/kg bd (depending on when the onset of symptoms is more common, e.g.                                              night  only, or both during the day and night

Adults -                                      25mg at night (may increase to TWICE daily in resistant cases)

 
Continue for a total of 4 weeks, then stop/wean depending on recurrence 
Monitor blood pressure (follow up at 1 week and then monthly)

  dobutamine On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

DOBUTAMINE

Injection formulation is Hospital Only

  Solution for infusion
Dobutamine (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Dobutamine

Injection formulation is Hospital Only

  dopamine hydrochloride On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

DOPAMINE HYDROCHLORIDE

Injection formulation is Hospital Only

  Solution for infusion
Dopamine hydrochloride (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Dopamine

Injection formulation is Hospital Only

  ephedrine hydrochloride On Formulary
EPHEDRINE HYDROCHLORIDE

Injection formulation is Hospital Only

  Solution for injection
Ephedrine hydrochloride (Non-proprietary) On Formulary
Ephedrine Hydrochloride

Injection formulation is Hospital Only

  metaraminol On Formulary
METARAMINOL

Injection formulation is Hospital Only

  Solution for injection
Metaraminol (Non-proprietary) On Formulary
Metaraminol

Injection formulation is Hospital Only

  noradrenaline/norepinephrine On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

NORADRENALINE/NOREPINEPHRINE

Injection formulation is Hospital Only

  Solution for infusion
Noradrenaline/norepinephrine (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Noradrenaline/Norepinephrine

Injection formulation is Hospital Only

  phenylephrine hydrochloride On Formulary
NEONATAL FORMULARY VERSION 9 2016 BARTS HEALTH

PHENYLEPHRINE HYDROCHLORIDE

Injection formulation is Hospital Only

  Solution for injection
Phenylephrine hydrochloride (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 9 2016 BARTS HEALTH

see attached

Phenylephrine

Injection formulation is Hospital Only

  sodium nitroprusside On Formulary
SODIUM NITROPRUSSIDE

Injection formulation is Hospital Use Only

  Powder and solvent for solution for infusion
Sodium nitroprusside (Non-proprietary) On Formulary
Sodium Nitroprusside

Injection formulation is Hospital Use Only

Cardiovascular system / Arrhythmias
  adenosine On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

  Solution for injection
Adenosine (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

Adenosine

Injection formulation is for Hospital Use Only

  Solution for infusion
Adenosine (Non-proprietary) On Formulary
Adenosine

Injection formulation is for Hospital Use Only

NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

  amiodarone hydrochloride On Formulary
AMIODARONE HYDROCHLORIDE

Supra-ventricular and ventricular arrhythmias.
 
 

  Solution for injection
Amiodarone hydrochloride (Non-proprietary) On Formulary
Amiodarone

Injection formulation is for Hospital Use Only

Cordarone X (Sanofi) On Formulary
  atenolol On Formulary
  atropine sulfate On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

  digoxin On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

  Solution for injection
Digoxin (Non-proprietary) Hospital Only
  esmolol hydrochloride On Formulary
  Solution for injection
Esmolol hydrochloride (Non-proprietary) Hospital Only
Brevibloc (Baxter Healthcare Ltd) On Formulary
  Solution for infusion
Brevibloc (Baxter Healthcare Ltd) On Formulary
Brevibloc®

Injection formulation is for Hospital Use Only

  flecainide acetate On Formulary
  lidocaine hydrochloride On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

The Association of Paediatric Palliative Medicine Formulary - 2015

see attached

  Solution for injection
Lidocaine hydrochloride (Non-proprietary) On Formulary
The Association of Paediatric Palliative Medicine Formulary - 2015

see attached

NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

Lidocaine

Injection formulation is for Hospital Use Only

  metoprolol tartrate On Formulary
  propranolol hydrochloride On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

  Oral solution
Propranolol hydrochloride (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

  sotalol hydrochloride On Formulary
  verapamil hydrochloride On Formulary
  Oral solution
Verapamil hydrochloride (Non-proprietary) On Formulary
  Solution for injection
Securon (Viatris UK Healthcare Ltd) On Formulary
Cardiovascular system / Blocked catheters and lines
  epoprostenol Hospital Only
  Powder and solvent for solution for infusion
Flolan (GlaxoSmithKline UK Ltd) Hospital Only
  heparin (unfractionated) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

  Solution for injection
Heparin (unfractionated) (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Neonatal Formulary Version 9 2016 Barts Health

Heparin Sodium

Injection formulation is Hospital Only

  Infusion
Heparin (unfractionated) (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Neonatal Formulary Version 9 2016 Barts Health

  Form unstated
Heparin (unfractionated) (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Neonatal Formulary Version 9 2016 Barts Health

Heparin flushes

Injection formulation is Hospital Use Only

  urokinase On Formulary
Cardiovascular system / Thromboembolism
  Rivaroxaban On Formulary
Rivaroxaban counselling checklist

Rivaroxaban counselling checklist

Rivaroxaban Transfer of Care Guideline (shared care - GP)

Rivaroxaban Transfer of Care Guideline (shared care - GP)

  alteplase On Formulary
  Powder and solvent for solution for injection
Actilyse (Boehringer Ingelheim Ltd) On Formulary
Actilyse®

Injection formulation is Hospital Use Only

  Powder and solvent for solution for infusion
Actilyse (Boehringer Ingelheim Ltd) On Formulary
Actilyse®

Injection formulation is Hospital Use Only

  aspirin On Formulary
  dalteparin sodium On Formulary
DALTEPARIN SODIUM

Enoxaparin is the LMWH of choice in neonates for administration & dose measurement reasons.

The use of Low Molecular Weight Heparin (LMWH) in Paediatric Patients

Guidelines for Prevention of Paediatric Thromboembolism

DALTEPARIN SODIUM

Injection formulation is Hospital Use Only

Restricted for use in children over one year old

  Solution for injection
Fragmin (Pfizer Ltd) On Formulary
Barts Health Paediatric DVT Prophylaxis Guideline

The use of Low Molecular Weight Heparin (LMWH) in Paediatric Patients

Fragmin®

Injection formulation is Hospital Use Only

Restricted for use in children over 1 year old

  danaparoid sodium On Formulary
  Solution for injection
Danaparoid sodium (Non-proprietary) On Formulary
Note

Injection formulation is Hospital Use Only

  dipyridamole On Formulary
  Oral suspension
Dipyridamole (Non-proprietary) On Formulary
  enoxaparin sodium On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

ENOXAPARIN SODIUM

Injection formulation is Hospital Use Only

Restricted for use in children less than one year of age

Dalteparin is Low Molecular Weight Heparin of Choice for Children greater than one year of age

  Solution for injection
Clexane (Sanofi) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Clexane®

Injection formulation is Hospital Use Only

Restricted for use in children less than one year of age

Dalteparin is Low Molecular Weight Heparin of Choice for Children greater than one year of age

  heparin (unfractionated) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

  Solution for injection
Heparin (unfractionated) (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Neonatal Formulary Version 9 2016 Barts Health

Heparin Sodium

Injection formulation is Hospital Only

  Infusion
Heparin (unfractionated) (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Neonatal Formulary Version 9 2016 Barts Health

  Form unstated
Heparin (unfractionated) (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Neonatal Formulary Version 9 2016 Barts Health

Heparin flushes

Injection formulation is Hospital Use Only

  streptokinase On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

STREPTOKINASE

Injection formulation is Hospital Use Only

  tinzaparin sodium On Formulary
TINZAPARIN SODIUM

Injection formulation is Hospital Use Only

Dalteparin is First Line for Children over 1 year

  urokinase On Formulary
  warfarin sodium On Formulary
  Oral suspension
Warfarin sodium (Non-proprietary) On Formulary
Cardiovascular system / Bleeding disorders
  tranexamic acid On Formulary
The Association of Paediatric Palliative Medicine Formulary - 2017

see attcahed

  Solution for injection
Tranexamic acid (Non-proprietary) On Formulary
Tranexamic acid

Injection formulation is Hospital Use Only

The Association of Paediatric Palliative Medicine Formulary - 2015

see attached

Cardiovascular system / Coagulation factor deficiencies
  dried prothrombin complex [Specialist drug] On Formulary
Availability of haemostatic agents across Barts Health sites

see attached

  factor VIIa (recombinant) [Specialist drug] On Formulary
Availability of haemostatic agents across Barts Health sites

see attached

Cardiovascular system / Subarachnoid haemorrhage
  nimodipine On Formulary
Cardiovascular system / Patent ductus arteriosus
  dinoprostone Hospital Only
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

  Solution for infusion
Prostin E2 (Pfizer Ltd) Hospital Only
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

  ibuprofen On Formulary
IBUPROFEN

Injection formulation is Hospital Use Only

The Association of Paediatric Palliative Medicine Formulary - 2015

see attached

NEONATAL FORMULARY BARTS HEALTH 2018 v10

see attached

  Solution for infusion
Pedea (Recordati Rare Diseases UK Ltd) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

Pedea®

Injection formulation is Hospital Use Only

Cardiovascular system / Hyperlipidaemia
  bezafibrate On Formulary
  colestyramine On Formulary
  ezetimibe On Formulary
  simvastatin On Formulary
Cardiovascular system / Myocardial ischaemia
  amlodipine On Formulary
  aspirin On Formulary
  atenolol On Formulary
  carvedilol On Formulary
CARVEDILOL

AF guidelines
 


 
Heart failure guidelines
 
https://www.nice.org.uk/guidance/ng106
 
Hypertension guidelines
 
https://pathways.nice.org.uk/pathways/hypertension
 
Secondary prevention of MI guidelines
https://pathways.nice.org.uk/pathways/myocardial-infarction-rehabilitation-and-preventing-further-cardiovascular-disease

Stable angina guidelines

https://www.nice.org.uk/guidance/cg126

  diltiazem hydrochloride On Formulary
  Modified-release tablet
Diltiazem hydrochloride (Non-proprietary) On Formulary
Retalzem (Kent Pharma (UK) Ltd) On Formulary
Tildiem (Sanofi) On Formulary
Tildiem Retard (Sanofi) On Formulary
  glyceryl trinitrate On Formulary
Glyceryl Trinitrate

Injection formulation is Hospital Only

  Solution for infusion
Glyceryl trinitrate (Non-proprietary) On Formulary
Glyceryl Trinitrate

Injection formulation is Hospital Only

  propranolol hydrochloride On Formulary
  Oral solution
Propranolol hydrochloride (Non-proprietary) On Formulary
  timolol maleate Off Formulary
  verapamil hydrochloride Off Formulary
Cardiovascular system / Acute coronary syndromes
  alteplase On Formulary
  Powder and solvent for solution for injection
Actilyse (Boehringer Ingelheim Ltd) On Formulary
Actilyse®

Injection formulation is Hospital Use Only

  Powder and solvent for solution for infusion
Actilyse (Boehringer Ingelheim Ltd) On Formulary
Actilyse®

Injection formulation is Hospital Use Only

  dalteparin sodium On Formulary
DALTEPARIN SODIUM

Enoxaparin is the LMWH of choice in neonates for administration & dose measurement reasons.

The use of Low Molecular Weight Heparin (LMWH) in Paediatric Patients

Guidelines for Prevention of Paediatric Thromboembolism

DALTEPARIN SODIUM

Injection formulation is Hospital Use Only

Restricted for use in children over one year old

  Solution for injection
Fragmin (Pfizer Ltd) On Formulary
Barts Health Paediatric DVT Prophylaxis Guideline

The use of Low Molecular Weight Heparin (LMWH) in Paediatric Patients

Fragmin®

Injection formulation is Hospital Use Only

Restricted for use in children over 1 year old

  enoxaparin sodium On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

ENOXAPARIN SODIUM

Injection formulation is Hospital Use Only

Restricted for use in children less than one year of age

Dalteparin is Low Molecular Weight Heparin of Choice for Children greater than one year of age

  Solution for injection
Clexane (Sanofi) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Clexane®

Injection formulation is Hospital Use Only

Restricted for use in children less than one year of age

Dalteparin is Low Molecular Weight Heparin of Choice for Children greater than one year of age

  glyceryl trinitrate On Formulary
Glyceryl Trinitrate

Injection formulation is Hospital Only

  Solution for infusion
Glyceryl trinitrate (Non-proprietary) On Formulary
Glyceryl Trinitrate

Injection formulation is Hospital Only

  heparin (unfractionated) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

  Solution for injection
Heparin (unfractionated) (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Neonatal Formulary Version 9 2016 Barts Health

Heparin Sodium

Injection formulation is Hospital Only

  Infusion
Heparin (unfractionated) (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Neonatal Formulary Version 9 2016 Barts Health

  Form unstated
Heparin (unfractionated) (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Neonatal Formulary Version 9 2016 Barts Health

Heparin flushes

Injection formulation is Hospital Use Only

  lisinopril
  Oral solution
Lisinopril (Non-proprietary) On Formulary
Cardiovascular system / Cardiac arrest
  adrenaline/epinephrine On Formulary
Adrenaline - inpatients


For inpatient management - refer to anaphylaxis guideline and use adrenaline AMPOULES 1:1000

(not Epipen or Emerade or Jext)

Anaphylaxis paediatric guideline

see attached

NEONATAL FORMULARY VERSION 10 2018 BARTS HEALTH

see attached

ADRENALINE/EPINEPHRINE

Injection formulation is Hospital Only

Except for IM injection (Emerade, Jext, Epipen)

Paediatric Oncology GOSH Supportive care protocol 2018

see attached

  Solution for injection
Adrenaline/epinephrine (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

Adrenaline/Epinephrine 1 in 1000

Injection formulation is Hospital Only

Adrenaline - inpatients


For inpatient management - refer to anaphylaxis guideline and use adrenaline AMPOULES 1:1000

(not Epipen or Emerade or Jext)

EpiPen (Viatris UK Healthcare Ltd) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

Adrenaline/Epinephrine 1 in 10 000, Dilute

Injection formulation is Hospital Use Only

Jext (ALK-Abello Ltd) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

Cardiovascular system / Oedema
  CO-AMILOFRUSE On Formulary
  amiloride hydrochloride On Formulary
AMILORIDE HYDROCHLORIDE

Heart failure guidelines
 

https://www.nice.org.uk/guidance/ng106

  Oral solution
Amiloride hydrochloride (Non-proprietary) On Formulary
  bumetanide On Formulary
BUMETANIDE

Injection formulation is for Hospital Use Only

Bumetanide may be better absorbed from an oedematous bowel.

  Oral solution
Bumetanide (Non-proprietary) On Formulary
  diamorphine hydrochloride Off Formulary
National supply shortage of Diamorphine 5mg and 10mg Injections

The trust has received notification from the Department of Health & Social Care regarding a national supply shortage of Diamorphine 5mg and 10mg Injections. This shortage is anticipated to last until summer 2020. Please see the memo attached for further information for this drug shortage.

Intranasal diamorphine - Formulary

See Paediatric acute sickle cell pain guideline

  furosemide On Formulary
Agreed standard strength - paediatrics

Furosemide

50mg/5ml should be used for all doses 1mg or greater

40mg/5ml should not be used in paediatrics

20mg/5ml is reserved for Neonatal doses <1mg

NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

FUROSEMIDE

Injection formulation is for Hospital Use Only

Furosemide

For use in heart failure. No longer licensed for use in hypertension.

  Oral solution
Furosemide (Non-proprietary) On Formulary
Agreed standard strenghts - paediatric

Furosemide

50mg/5ml should be used for all doses 1mg or greater

40mg/5ml should not be used in paediatrics

20mg/5ml is reserved for Neonatal doses <1mg

NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

Furosemide

For use in heart failure. No longer licensed for use in hypertension.

  Solution for injection
Furosemide (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

Furosemide

For use in heart failure. No longer licensed for use in hypertension.

Injection formulation is for Hospital Use Only

  mannitol On Formulary
  Infusion
Mannitol (Non-proprietary) On Formulary
Mannitol

Injection formulation is for Hospital Use Only

Cystic Fibrosis Drug Doses

CF Drug Doses 2015

  metolazone On Formulary
Cardiovascular system / Ascites
  spironolactone On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Agreed standard strengths

Spironolactone

50mg/5ml to be used for all doses of 1mg or higher

10mg/5ml is reserved for neonatal doses under 1mg- not to be used on discharge

 

Spironolactone

Note: Only 50mg/5mL suspension is ON FORMULARY.

SPIRONOLACTONE

For use in heart failure, ascites, hypertension, and nephrotic syndrome.

Heart failure guidelines

https://www.nice.org.uk/guidance/ng106

 
Hypertension guidelines

https://pathways.nice.org.uk/pathways/hypertension

Cardiovascular system / Cardiac diagnostic procedures and surgeries
  dobutamine On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

DOBUTAMINE

Injection formulation is Hospital Only

  Solution for infusion
Dobutamine (Non-proprietary) On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Dobutamine

Injection formulation is Hospital Only

Cardiovascular system / Heart failure
  bendroflumethiazide On Formulary
BENDROFLUMETHIAZIDE

Note: NICE no longer recommends for hypertension (unless in the treatment of the diabetic - see necessary guidelines).

Hypertension guidelines

http://www.nice.org.uk/guidance/CG127

  captopril On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

  digoxin On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

  Solution for injection
Digoxin (Non-proprietary) Hospital Only
  enalapril maleate On Formulary
  enoximone On Formulary
  Solution for injection
Perfan (Macure Pharma UK Ltd) On Formulary
Perfan®

Injection formulation is for Hospital Use Only

  glyceryl trinitrate On Formulary
Glyceryl Trinitrate

Injection formulation is Hospital Only

  Solution for infusion
Glyceryl trinitrate (Non-proprietary) On Formulary
Glyceryl Trinitrate

Injection formulation is Hospital Only

  lisinopril On Formulary
  Oral solution
Lisinopril (Non-proprietary) On Formulary
  potassium canrenoate On Formulary
POTASSIUM CANRENOATE

Injection formulation is for Hospital Use Only

NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

see attached

  Solution for injection
Potassium canrenoate (Non-proprietary) On Formulary
  sodium nitroprusside On Formulary
SODIUM NITROPRUSSIDE

Injection formulation is Hospital Use Only

  Powder and solvent for solution for infusion
Sodium nitroprusside (Non-proprietary) On Formulary
Sodium Nitroprusside

Injection formulation is Hospital Use Only

  spironolactone On Formulary
NEONATAL FORMULARY VERSION 8 2015 BARTS HEALTH

Agreed standard strengths

Spironolactone

50mg/5ml to be used for all doses of 1mg or higher

10mg/5ml is reserved for neonatal doses under 1mg- not to be used on discharge

 

Spironolactone

Note: Only 50mg/5mL suspension is ON FORMULARY.

SPIRONOLACTONE

For use in heart failure, ascites, hypertension, and nephrotic syndrome.

Heart failure guidelines

https://www.nice.org.uk/guidance/ng106

 
Hypertension guidelines

https://pathways.nice.org.uk/pathways/hypertension