| Blood and blood-forming organs | |||||
|---|---|---|---|---|---|
| Blood and blood-forming organs / Hypoplastic, haemolytic, and renal anaemias | |||||
| darbepoetin alfa | Hospital Only |
NICE TA323 |
|||
| Solution for injection | |||||
| Aranesp (Amgen Ltd) | On Formulary | ||||
| Aranesp SureClick (Amgen Ltd) | On Formulary | ||||
| eltrombopag | Hospital Only |
NICE TA293 |
|||
|
Treatment pathway for non-pregnant adult patients with immune thrombocytopenia (ITP)
|
|||||
| Oral tablet | |||||
| Eltrombopag (Non-proprietary) | |||||
| Revolade (Novartis Pharmaceuticals UK Ltd) | |||||
| Powder for oral suspension | |||||
| Revolade (Novartis Pharmaceuticals UK Ltd) | |||||
| epoetin alfa | Off Formulary |
NICE TA323 |
|||
| Solution for injection | |||||
| Eprex (Janssen-Cilag Ltd) | |||||
| epoetin beta | Hospital Only |
NICE TA323 |
|||
| Solution for injection | |||||
| NeoRecormon (Roche Products Ltd) | Hospital Only | ||||
| epoetin zeta | Hospital Only |
NICE TA323 |
|||
|
Erythropoietin oncology prescription proforma
See attached |
|||||
| Solution for injection | |||||
| Retacrit (Pfizer Ltd) | |||||
| methoxy polyethylene glycol-epoetin beta | On Formulary | ||||
|
METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
Please note that injections are HOSPITAL ONLY. |
|||||
| Solution for injection | |||||
| Mircera (Roche Products Ltd) | Hospital Only | ||||
|
Mircera®
Please note that injections are HOSPITAL ONLY. |
|||||
| oxymetholone | Off Formulary | ||||
| Oral capsule | |||||
| Oxymetholone (Non-proprietary) | |||||
| roxadustat | Hospital Only |
NICE TA807 |
|||
|
NICE TA 807 (July 2022) Roxadustat for treating Symptomatic Anaemia in Chronic Kidney Disease
Roxadustat is recommended to treat Symptomatic anaemia associated with chronic kidney disease (CKD) in adults only if: • They have stage 3 to 5 CKD with no iron deficiency and • They are not on dialysis at the start of treatment |
|||||
| Oral tablet | |||||
| Evrenzo (Astellas Pharma Ltd) | |||||
| Blood and blood-forming organs / Sickle-cell disease | |||||
| crizanlizumab | Hospital Only |
NICE TA743 |
|||
| hydroxycarbamide | On Formulary | ||||
|
Thalassaemia Trust Policies
see attached |
|||||
|
HOSPITAL ONLY
EXCEPT AS PART OF SHARED CARE |
|||||
|
Hydroxyurea shared care guidance
HYDROXYCARBAMIDE (HYDROXYUREA) For the Management of Sickle Cell Disease in Adults and Children |
|||||
| Oral solution | |||||
| Xromi (Nova Laboratories Ltd) | |||||
| Oral tablet | |||||
| Siklos (Masters Pharmaceuticals Ltd) | |||||
| Oral capsule | |||||
| Hydroxycarbamide (Non-proprietary) | |||||
| Droxia (Imported (United States)) | |||||
| Hydrea (Neon Healthcare Ltd) | |||||
| voxelotor | Off Formulary |
NICE TA981 |
|||
| Oral tablet | |||||
| Oxbryta (Pfizer Ltd) | |||||
| Blood and blood-forming organs / Atypical haemolytic uraemic syndrome and paroxysmal nocturnal haemoglobinuria | |||||
| eculizumab | Hospital Only |
NICE HST1 |
|||
|
Eculizumab
aHUS: Funding required from NHSE prior to prescribing |
|||||
|
ECULIZUMAB
Per NHSE criteria |
|||||
|
Paroxysmal nocturnal haemoglobinuria and atypical haemolytic uraemic syndrome
On formulary for aHUS per NHSE criteria |
|||||
| Solution for infusion | |||||
| Bekemv (Amgen Ltd) | |||||
| Epysqli (Samsung Bioepis NL B.V. Ltd) | |||||
| Soliris (Alexion Pharma UK Ltd) | On Formulary | ||||
|
Eculizumab
aHUS: Funding required from NHSE prior to prescribing |
|||||
|
Soliris®
Per NHSE criteria |
|||||
|
Paroxysmal nocturnal haemoglobinuria and atypical haemolytic uraemic syndrome
On formulary for aHUS per NHSE criteria |
|||||
| pegcetacoplan |
NICE TA778 |
||||
| Solution for infusion | |||||
| Aspaveli (Swedish Orphan Biovitrum Ltd) | |||||
| ravulizumab | Hospital Only |
NICE TA698 NICE TA710 |
|||
|
Approved for Atypical haemolytic uraemic syndrome only
As per NICE TA 710- commissioned by NHSE (Hospital Only). October 2021 DTC. |
|||||
| Solution for infusion | |||||
| Ultomiris (Alexion Pharma UK Ltd) | |||||
| Blood and blood-forming organs / Iron deficiency anaemia | |||||
| ferric carboxymaltose | Hospital Only | ||||
| Solution for injection | |||||
| Ferinject (Vifor Pharma UK Ltd) | On Formulary | ||||
| ferric derisomaltose | Hospital Only | ||||
|
IRON ISOMALTOSIDE 1000
Monofer First line for outpatients, maternity, clinical haematology, peritoneal dialysis, general nephrology, transplant & suppoprtive care patients
Diafer First line for renal haemodialysis patients |
|||||
|
Monofer to the generic name of Ferric Derisomaltose, April 2023.
The name change has been made on the 3rd of April 2023 from the manufacturers. |
|||||
| Solution for injection | |||||
| Ferric derisomaltose (Non-proprietary) | |||||
| Diafer (Pharmacosmos UK Ltd) | Hospital Only | ||||
| ferric maltol | Off Formulary | ||||
| Oral capsule | |||||
| Feraccru (Norgine Pharmaceuticals Ltd) | |||||
| ferrous fumarate | On Formulary | ||||
| Oral solution | |||||
| Ferrous fumarate (Non-proprietary) | On Formulary | ||||
| AacuFer (TriOn Pharma Ltd) | |||||
| AadFer (Essential-Healthcare Ltd) | |||||
| FerroEss (Essential-Healthcare Ltd) | |||||
| Galfer (Thornton & Ross Ltd) | On Formulary | ||||
| Oral tablet | |||||
| Ferrous fumarate (Non-proprietary) | |||||
| FerroDose-F (TriOn Pharma Ltd) | |||||
| FerroEss (Essential-Healthcare Ltd) | |||||
| Oral capsule | |||||
| Ferrous fumarate (Non-proprietary) | |||||
| FerroDose-F (TriOn Pharma Ltd) | |||||
| FerroEss (Essential-Healthcare Ltd) | |||||
| Galfer (Thornton & Ross Ltd) | |||||
| ferrous fumarate with folic acid | Off Formulary | ||||
| ferrous gluconate | On Formulary | ||||
| Oral tablet | |||||
| Ferrous gluconate (Non-proprietary) | |||||
| AadFer (Essential-Healthcare Ltd) | |||||
| FerroDose-G (TriOn Pharma Ltd) | |||||
| ferrous sulfate | On Formulary | ||||
| Modified-release tablet | |||||
| Ferrograd (Teofarma S.r.l.) | |||||
| Oral drops | |||||
| Ferrous sulfate (Non-proprietary) | |||||
| FerroNorm (Essential-Healthcare Ltd) | |||||
| Oral tablet | |||||
| Ferrous sulfate (Non-proprietary) | |||||
| FerroDose-S (TriOn Pharma Ltd) | |||||
| FerroTab (Essential-Healthcare Ltd) | |||||
| ferrous sulfate with ascorbic acid | Off Formulary | ||||
| Modified-release tablet | |||||
| Ferrograd C (Teofarma S.r.l.) | |||||
| ferrous sulfate with folic acid | Off Formulary | ||||
| Modified-release tablet | |||||
| Ferrograd Folic (Teofarma S.r.l.) | |||||
| iron dextran | On Formulary | ||||
|
IRON DEXTRAN
FOR HOSPITAL USE ONLY |
|||||
| Solution for injection | |||||
| CosmoFer (Pharmacosmos UK Ltd) | On Formulary | ||||
|
CosmoFer®
FOR HOSPITAL USE ONLY |
|||||
| iron sucrose | Hospital Only | ||||
|
IRON SUCROSE
FOR HOSPITAL USE ONLY |
|||||
| Solution for injection | |||||
| Venofer (Imported (United States), Vifor Pharma UK Ltd) | On Formulary | ||||
|
Venofer®
FOR HOSPITAL USE ONLY |
|||||
| sodium feredetate | On Formulary | ||||
| Oral solution | |||||
| Sodium feredetate (Non-proprietary) | |||||
| Sytron (Kyowa Kirin International UK NewCo Ltd) | On Formulary | ||||
| Blood and blood-forming organs / Megaloblastic anaemia | |||||
| cyanocobalamin | On Formulary | ||||
|
CYANOCOBALAMIN
Only tablets and injection kept in Pharmacy |
|||||
| Oral tablet | |||||
| Cyanocobalamin (Non-proprietary) | |||||
| CyanocoB12 (TriOn Pharma Ltd) | |||||
| CyanocoMinn (Essential-Healthcare Ltd) | |||||
| Orobalin (Northumbria Pharma Ltd) | |||||
| SunVit-Pro (SunVit-D3 Ltd) | |||||
| folic acid | On Formulary | ||||
|
FOLIC ACID
INJECTION FORMULATION IS FOR HOSPITAL USE ONLY |
|||||
| Oral solution | |||||
| Folic acid (Non-proprietary) | On Formulary | ||||
| Lexpec (Rosemont Pharmaceuticals Ltd) | |||||
| Oral tablet | |||||
| Folic acid (Non-proprietary) | |||||
| hydroxocobalamin | On Formulary | ||||
|
HYDROXOCOBALAMIN
HOSPITAL USE ONLY for emergency treatment of poisoning |
|||||
| Solution for injection | |||||
| Hydroxocobalamin (Non-proprietary) | On Formulary | ||||
| Cobalin (Advanz Pharma) | |||||
| Neo-Cytamen (RPH Pharmaceuticals AB) | |||||
| Powder for solution for infusion | |||||
| Cyanokit (SERB) | |||||
|
For moderate or severe cyanide poisoning-See antidote list
. |
|||||
|
For moderate or severe cyanide poisoning-See antidote list
. |
|||||
| Blood and blood-forming organs / Iron overload | |||||
| deferasirox | Hospital Only | ||||
|
Thalassaemia Trust Policies
see attached |
|||||
|
Exjade Dosing guidance
|
|||||
| Oral tablet | |||||
| Deferasirox (Non-proprietary) | |||||
| Exjade (Novartis Pharmaceuticals UK Ltd) | |||||
| deferiprone | Hospital Only | ||||
|
Management of Thalassaemia - Trust Policies
See below |
|||||
| Oral solution | |||||
| Ferriprox (Chiesi Ltd) | |||||
|
Ferriprox®
FOR HOSPITAL USE ONLY |
|||||
|
Thalassaemia in adults Trust Guideline
see attached |
|||||
| Oral tablet | |||||
| Deferiprone (Non-proprietary) | |||||
| Ferriprox (Chiesi Ltd) | |||||
| desferrioxamine mesilate | Hospital Only | ||||
|
Trust Policies Thalassaemia in Adults
see attached |
|||||
| Powder for solution for injection | |||||
| Desferrioxamine mesilate (Non-proprietary) | On Formulary | ||||
|
Thalassaemia in adults Trust Guideline
|
|||||
|
Desferrioxamine mesilate
FOR HOSPITAL USE ONLY |
|||||
| Desferal (Novartis Pharmaceuticals UK Ltd) | On Formulary | ||||
|
Thalassaemia in adults Trust Guideline
|
|||||
|
Desferal®
FOR HOSPITAL USE ONLY |
|||||
| Blood and blood-forming organs / Neutropenia | |||||
| filgrastim | Hospital Only | ||||
|
FILGRASTIM
FOR HOSPITAL USE ONLY |
|||||
|
Guidelines
Use of Haematopoietic Growth Factors in Adult Oncology and Haemato-oncology Patients |
|||||
| Solution for injection | |||||
| Accofil (Accord-UK Ltd) | Off Formulary | ||||
| Neupogen (Amgen Ltd) | Off Formulary | ||||
|
FILGRASTIM
FOR HOSPITAL USE ONLY |
|||||
| Neupogen Singleject (Amgen Ltd) | Off Formulary | ||||
|
FILGRASTIM
FOR HOSPITAL USE ONLY |
|||||
| Nivestim (Pfizer Ltd) | Off Formulary | ||||
| Zarzio (Sandoz Ltd) | Hospital Only | ||||
|
Zarzio®
FOR HOSPITAL USE ONLY |
|||||
|
FILGRASTIM
FOR HOSPITAL USE ONLY |
|||||
| lenograstim | On Formulary | ||||
|
LENOGRASTIM
FOR HOSPITAL USE ONLY |
|||||
|
Guidelines
Use of Haematopoietic Growth Factors in Adult Oncology and Haemato-oncology Patients |
|||||
| Powder and solvent for solution for injection | |||||
| Granocyte (Chugai Pharma UK Ltd) | On Formulary | ||||
|
Granocyte®
FOR HOSPITAL USE ONLY |
|||||
| lipegfilgrastim | Off Formulary | ||||
|
Guidelines
Use of Haematopoietic Growth Factors in Adult Oncology and Haemato-oncology Patients |
|||||
| Solution for injection | |||||
| Lonquex (Teva UK Ltd) | |||||
| pegfilgrastim | Off Formulary | ||||
|
Guidelines
Use of Haematopoietic Growth Factors in Adult Oncology and Haemato-oncology Patients |
|||||
| Solution for injection | |||||
| Neulasta (Amgen Ltd) | On Formulary | ||||
| Pelgraz (Accord-UK Ltd) | |||||
| Pelmeg (Napp Pharmaceuticals Ltd) | |||||
| Ziextenzo (Sandoz Ltd) | |||||
| Blood and blood-forming organs / Stem cell mobilisation | |||||
| plerixafor | On Formulary | ||||
|
Plerixafor
|
|||||
| Solution for injection | |||||
| Plerixafor (Non-proprietary) | |||||
| Mozobil (Sanofi) | On Formulary | ||||
|
Plerixafor
|
|||||
| Blood and blood-forming organs / Essential thrombocythaemia | |||||
| anagrelide [Specialist drug] | Hospital Only | ||||
| Oral capsule | |||||
| Anagrelide (Non-proprietary) | |||||
| Xagrid (Takeda UK Ltd) | |||||
| hydroxycarbamide | Hospital Only | ||||
|
Hydroxyurea shared care guidance
HYDROXYCARBAMIDE (HYDROXYUREA) For the Management of Sickle Cell Disease in Adults and Children |
|||||
| Oral solution | |||||
| Xromi (Nova Laboratories Ltd) | |||||
| Oral tablet | |||||
| Siklos (Masters Pharmaceuticals Ltd) | |||||
| Oral capsule | |||||
| Hydroxycarbamide (Non-proprietary) | |||||
| Droxia (Imported (United States)) | |||||
| Hydrea (Neon Healthcare Ltd) | |||||
| Blood and blood-forming organs / Thrombocytopenias | |||||
| avatrombopag | On Formulary |
NICE TA626 NICE TA853 |
|||
|
Avatrombopag for primary chronic immune thrombocytopenia, NICE TA 853, February 2023
Approved at NEL FPG for primary chronic immune thrombocytopenia in line with NICE TA 853. |
|||||
| Oral tablet | |||||
| Doptelet (Swedish Orphan Biovitrum Ltd) | |||||
| lusutrombopag | Hospital Only |
NICE TA617 |
|||
| Oral tablet | |||||
| Mulpleo (Shionogi BV) | |||||
| Blood and blood-forming organs / Acquired thrombotic thrombocytopenic purpura | |||||
| caplacizumab |
NICE TA667 |
||||
| Powder and solvent for solution for injection | |||||
| Cablivi (Sanofi) | |||||
| Blood and blood-forming organs / Immune thrombocytopenia | |||||
| eltrombopag | Hospital Only |
NICE TA293 |
|||
| Oral tablet | |||||
| Eltrombopag (Non-proprietary) | |||||
| Revolade (Novartis Pharmaceuticals UK Ltd) | |||||
| Powder for oral suspension | |||||
| Revolade (Novartis Pharmaceuticals UK Ltd) | |||||
| fostamatinib | On Formulary |
NICE TA835 |
|||
|
Fostamatinib for treating refractory chronic immune thrombocytopenia, NICE TA 835, January 2023
Approved at NEL FPG for treating refractory chronic immune thrombocytopenia in line with NICE TA 835. |
|||||
| Oral tablet | |||||
| Tavlesse (Grifols UK Ltd) | |||||
| romiplostim | Hospital Only |
NICE TA221 |
|||
| Powder for solution for injection | |||||
| Nplate (Amgen Ltd) | |||||
| Powder and solvent for solution for injection | |||||
| Nplate (Amgen Ltd) | |||||