| Blood and blood-forming organs | |||||
|---|---|---|---|---|---|
| Blood and blood-forming organs / Hypoplastic, haemolytic, and renal anaemias | |||||
| darbepoetin alfa | Hospital Only | ||||
|
DARBEPOETIN ALFA
For Hospital Use Only |
|||||
| Solution for injection | |||||
| Aranesp (Amgen Ltd) | On Formulary | ||||
|
Aranesp®
For Hospital Use Only |
|||||
| Aranesp SureClick (Amgen Ltd) | On Formulary | ||||
|
Aranesp®
For Hospital Use Only |
|||||
| eltrombopag | Hospital Only | ||||
|
ELTROMBOPAG
For Hospital use only |
|||||
| epoetin alfa | Hospital Only | ||||
|
EPOETIN ALFA
For Hospital use only |
|||||
| Solution for injection | |||||
| Eprex (Janssen-Cilag Ltd) | Hospital Only | ||||
| epoetin beta | Hospital Only | ||||
|
EPOETIN BETA
For Hospital use only |
|||||
| Solution for injection | |||||
| NeoRecormon (Roche Products Ltd) | Hospital Only | ||||
| epoetin zeta | Hospital Only | ||||
|
EPOETIN ZETA
For Hospital use only |
|||||
| Solution for injection | |||||
| Retacrit (Pfizer Ltd) | Hospital Only | ||||
| oxymetholone | On Formulary | ||||
| Blood and blood-forming organs / Sickle-cell disease | |||||
| hydroxycarbamide | On Formulary | ||||
|
Sickle-Cell-Disease Management in Children
see attached |
|||||
|
Siklos - hydroxycarbamide tablet (paediatrics)
Siklos tablets can be used 2nd line in children with sickle cell disease if difficulty swallowing capsules. Tablets are significantly more expensive than capsules. SPC states 100mg Siklos tablets can be halved, and 1g tablets can be quartered for ease of dose rounding. |
|||||
|
Difficult to Obtain Letter
see attached |
|||||
| Blood and blood-forming organs / Atypical haemolytic uraemic syndrome and paroxysmal nocturnal haemoglobinuria | |||||
| eculizumab | Off Formulary |
NICE HST1 |
|||
| Blood and blood-forming organs / Iron deficiency anaemia | |||||
| ferric carboxymaltose | Hospital Only | ||||
|
FERRIC CARBOXYMALTOSE
Hospital Use Only Treatment of iron deficiency anaemia in paediatric inflammatory bowel disease and intestinal failure. Indicated if Hb <100g/L, refractory/intolerant to oral iron Dose: 15mg/kg iron, maximum 20mg/kg iron to allow for dose rounding. Maximum single dose 1000mg/day and maximum cumulative dose 1000mg/week. For doses greater than 1000mg iron, split the dose and give at least 7 days apart. |
|||||
| Solution for injection | |||||
| Ferinject (Vifor Pharma UK Ltd) | On Formulary | ||||
|
Ferinject®
Hospital Use Only |
|||||
| ferrous fumarate | On Formulary | ||||
| Oral solution | |||||
| Ferrous fumarate (Non-proprietary) | On Formulary | ||||
| Galfer (Thornton & Ross Ltd) | On Formulary | ||||
| ferrous gluconate | On Formulary | ||||
| ferrous sulfate | On Formulary | ||||
|
Feospan modified-release capsules - restricted use in paediatrics (Manufacturer no longer supplying - Jan 2022)
Feospan m/r capsules were approved by DTC in December 2021 to treat iron deficiency anaema in children who are intolerant to Sytron (sodium feredetate) liquid and unable to take any other tablets/capsules. Modified-release preparations of iron should not routinely be used as they are less well absorbed. Feospan capsules should be prescribed from hospital only (not prescribable in NHS primary care). |
|||||
| ferrous sulfate with folic acid | Off Formulary | ||||
| iron dextran | On Formulary | ||||
| Solution for injection | |||||
| CosmoFer (Pharmacosmos UK Ltd) | On Formulary | ||||
|
CosmoFer®
Hospital Use Only |
|||||
| iron sucrose | On Formulary | ||||
| Solution for injection | |||||
| Venofer (Imported (United States), Vifor Pharma UK Ltd) | On Formulary | ||||
|
Venofer®
Hospital Use Only |
|||||
| sodium feredetate | On Formulary | ||||
|
NEONATAL FORMULARY VERSION 9 2016 BARTS HEALTH
|
|||||
| Oral solution | |||||
| Sytron (Kyowa Kirin International UK NewCo Ltd) | On Formulary | ||||
|
NEONATAL FORMULARY VERSION 9 2016 BARTS HEALTH
|
|||||
| Blood and blood-forming organs / Megaloblastic anaemia | |||||
| cyanocobalamin | On Formulary | ||||
| folic acid | On Formulary | ||||
|
NEONATAL FORMULARY VERSION 9 2016 BARTS HEALTH
|
|||||
| Oral solution | |||||
| Folic acid (Non-proprietary) | On Formulary | ||||
| hydroxocobalamin | On Formulary | ||||
| Solution for injection | |||||
| Hydroxocobalamin (Non-proprietary) | On Formulary | ||||
|
Hydroxocobalamin
For Hospital Use Only |
|||||
| Blood and blood-forming organs / Iron overload | |||||
| deferasirox | Hospital Only | ||||
|
Exjade dosing Guidance
|
|||||
|
DEFERASIROX
For Hospital Use Only |
|||||
| deferiprone | Hospital Only | ||||
|
DEFERIPRONE
For Hospital Use Only |
|||||
| Oral solution | |||||
| Ferriprox (Chiesi Ltd) | On Formulary | ||||
|
Ferriprox®
For Hospital Use Only |
|||||
| desferrioxamine mesilate | On Formulary | ||||
|
DESFERRIOXAMINE MESILATE
For Hospital Use Only |
|||||
| Powder for solution for injection | |||||
| Desferrioxamine mesilate (Non-proprietary) | On Formulary | ||||
|
Desferrioxamine mesilate
For Hospital Use Only |
|||||
| Blood and blood-forming organs / Neutropenia | |||||
| filgrastim | On Formulary | ||||
|
NEONATAL FORMULARY VERSION 9 2016 BARTS HEALTH
|
|||||
|
FILGRASTIM
For Hospital Use Only |
|||||
| Solution for injection | |||||
| Neupogen (Amgen Ltd) | Off Formulary | ||||
|
NEONATAL FORMULARY VERSION 9 2016 BARTS HEALTH
see attached |
|||||
|
Neupogen®
For Hospital Use Only |
|||||
| Neupogen Singleject (Amgen Ltd) | Off Formulary | ||||
|
NEONATAL FORMULARY VERSION 9 2016 BARTS HEALTH
see attached |
|||||
|
Neupogen®
For Hospital Use Only |
|||||
| Zarzio (Sandoz Ltd) | Hospital Only | ||||
|
NEONATAL FORMULARY VERSION 9 2016 BARTS HEALTH
|
|||||
| lenograstim | On Formulary | ||||
| Powder and solvent for solution for injection | |||||
| Granocyte (Chugai Pharma UK Ltd) | On Formulary | ||||
|
Granocyte®
For Hospital Use Only |
|||||
| Blood and blood-forming organs / Essential thrombocythaemia | |||||
| anagrelide [Specialist drug] | Hospital Only | ||||
|
ANAGRELIDE
For Hospital Use Only |
|||||
| hydroxycarbamide | On Formulary | ||||
|
Siklos - hydroxycarbamide tablet (paediatrics)
Siklos tablets can be used 2nd line in children with sickle cell disease if difficulty swallowing capsules. Tablets are significantly more expensive than capsules. SPC states 100mg Siklos tablets can be halved, and 1g tablets can be quartered for ease of dose rounding. |
|||||