Important update: Levemir (insulin detemir) Discontinuation

Posted on:

Novo Nordisk has decided to discontinue Levemir, Penfill, and Levemir FlexPen, with supplies expected to be discontinued by 31 December 2026.

There is no direct switch for Levemir (insulin detemir) and patients will need careful switching and additional monitoring when moving to alternative insulin products.

The NEL approach

The NEL Levemir Discontinuation Task and Finish Group, in consultation with the NEL Diabetes Improvement Network have agreed the following approach:

Acute and Specialist community diabetes teams will review all patients currently on their caseload prescribed Levemir?, as part of their routine diabetes reviews, including children and young people under paediatric care.

Paediatric and adolescent patients under the care of specialist diabetes teams should continue to be managed in accordance with local specialist pathways, supported by this approach to ensure alignment across NEL.

Switches may also take place in primary care where insulin initiation / ongoing management is being undertaken by:

  • Practice diabetes nurses
  • GPs with specialist interest
  • Pharmacists
  • Other suitably experienced clinicians.

Where needed, specialist diabetes teams can be contacted for:

  • Case-by-case discussion as part of a Multidisciplinary team meeting (MDT)
  • Advice and guidance.

All staff are advised to follow national clinical guidance: Discontinuation of Levemir (insulin detemir): Joint guidance from ABCD and PCDO Society.

Before switching, staff are advised to check the SPS Medicines Supply Tool for the most up-to-date supply information (see table below with supply information correct as of 13 February 2026 which is subject to change).

Further updates on stock availability and resources to support the identification of patients prescribed Levemir? and moving to alternative insulins in primary care will be provided shortly.

Immediate Actions

General practice and Primary Care Networks:

  • STOP initiating new patients on Levemir? FlexPen? or Penfill?.
  • Prioritise review of patients currently prescribed Levemir?, in line with national clinical guidance.
  • Diversify prescribing across recommended alternative insulins that can support demand.
  • Check stock availability before prescribing.

Community Pharmacy teams:

  • If a prescription for Levemir? is received:
    • Advise the patient that their GP or diabetes specialist will contact them to discuss an alternative insulin.
    • Reassure the patient that they will continue to receive insulin treatment.
    • Explain that Levemir? will be discontinued by December 2026.

Current alternative insulin availability from brands that can support increased demand (information correct as of 13 Feb 2026)

Insulin typeBrandStock statusAdditional information 
Insulin glargine U100 (Long acting)Semglee? pre-filled pens  Temporarily unavailable and resupply expected on 27Feb 2026.Consider Semglee? as first line option, where clinically appropriate, as it is the most cost-effective choice of glargine
Lantus? SoloStar? Lantus? cartridgesIn stock  
Insulin glargine U300 (Ultralong acting)Toujeo? Solostar? Toujeo? Doublestar?In stock
Insulin degludec U100/U200 (Ultralong acting)Tresiba? Penfill? cartridges U100 Tresiba? FlexTouch? U200In stockTresiba? FlexTouch? U100 pre-filled pen discontinued

Further information can be found in the guidance note.

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It is not for public use.

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